Innate Immunity of the Lung: From Basic Mechanisms to Translational Medicine
Hartl, Dominik, Tirouvanziam, Rabindra, Laval, Julie, Greene, Catherine M., Habiel, David, Sharma, Lokesh, Yildirim, Ali Önder, Dela Cruz, Charles S., Hogaboam, Cory M.
Published in Journal of innate immunity (01.01.2018)
Published in Journal of innate immunity (01.01.2018)
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Systems toxicology of complex wood combustion aerosol reveals gaseous carbonyl compounds as critical constituents
Dilger, Marco, Armant, Olivier, Ramme, Larissa, Mülhopt, Sonja, Sapcariu, Sean C., Schlager, Christoph, Dilger, Elena, Reda, Ahmed, Orasche, Jürgen, Schnelle-Kreis, Jürgen, Conlon, Thomas M., Yildirim, Ali Önder, Hartwig, Andrea, Zimmermann, Ralf, Hiller, Karsten, Diabaté, Silvia, Paur, Hanns-Rudolf, Weiss, Carsten
Published in Environment international (01.09.2023)
Published in Environment international (01.09.2023)
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TRPV4 channels are essential for alveolar epithelial barrier function as protection from lung edema
Weber, Jonas, Rajan, Suhasini, Schremmer, Christian, Chao, Yu-Kai, Krasteva-Christ, Gabriela, Kannler, Martina, Yildirim, Ali Önder, Brosien, Monika, Schredelseker, Johann, Weissmann, Norbert, Grimm, Christian, Gudermann, Thomas, Dietrich, Alexander
Published in JCI insight (15.10.2020)
Published in JCI insight (15.10.2020)
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Stimuli-Specific Senescence of Primary Human Lung Fibroblasts Modulates Alveolar Stem Cell Function
Melo-Narváez, Maria Camila, Bramey, Nora, See, Fenja, Heinzelmann, Katharina, Ballester, Beatriz, Steinchen, Carina, Jain, Eshita, Federl, Kathrin, Hu, Qianjiang, Dhakad, Deepesh, Behr, Jürgen, Eickelberg, Oliver, Yildirim, Ali Önder, Königshoff, Melanie, Lehmann, Mareike
Published in Cells (Basel, Switzerland) (29.06.2024)
Published in Cells (Basel, Switzerland) (29.06.2024)
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The Immunopathology of Pulmonary Rejection after Murine Lung Transplantation
Kaes, Janne, Pollenus, Emilie, Hooft, Charlotte, Liu, Hengshuo, Aelbrecht, Celine, Cambier, Seppe, Jin, Xin, Van Slambrouck, Jan, Beeckmans, Hanne, Kerckhof, Pieterjan, Velde, Greetje Vande, Van Raemdonck, Dirk, Yildirim, Ali Önder, Van den Steen, Philippe E, Vos, Robin, Ceulemans, Laurens J, Vanaudenaerde, Bart M
Published in Cells (Basel, Switzerland) (01.01.2024)
Published in Cells (Basel, Switzerland) (01.01.2024)
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Inhibition of LTβR signalling activates WNT-induced regeneration in lung
Conlon, Thomas M., John-Schuster, Gerrit, Heide, Danijela, Pfister, Dominik, Lehmann, Mareike, Hu, Yan, Ertüz, Zeynep, Lopez, Martin A., Ansari, Meshal, Strunz, Maximilian, Mayr, Christoph, Angelidis, Ilias, Ciminieri, Chiara, Costa, Rita, Kohlhepp, Marlene Sophia, Guillot, Adrien, Günes, Gizem, Jeridi, Aicha, Funk, Maja C., Beroshvili, Giorgi, Prokosch, Sandra, Hetzer, Jenny, Verleden, Stijn E., Alsafadi, Hani, Lindner, Michael, Burgstaller, Gerald, Becker, Lore, Irmler, Martin, Dudek, Michael, Janzen, Jakob, Goffin, Eric, Gosens, Reinoud, Knolle, Percy, Pirotte, Bernard, Stoeger, Tobias, Beckers, Johannes, Wagner, Darcy, Singh, Indrabahadur, Theis, Fabian J., de Angelis, Martin Hrabé, O’Connor, Tracy, Tacke, Frank, Boutros, Michael, Dejardin, Emmanuel, Eickelberg, Oliver, Schiller, Herbert B., Königshoff, Melanie, Heikenwalder, Mathias, Yildirim, Ali Önder
Published in Nature (London) (03.12.2020)
Published in Nature (London) (03.12.2020)
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Small Airway Disease in Pre-Chronic Obstructive Pulmonary Disease with Emphysema: A Cross-Sectional Study
Verleden, Stijn E, Hendriks, Jeroen M H, Snoeckx, Annemiek, Mai, Cindy, Mentens, Yves, Callebaut, Wim, De Belie, Bruno, Van Schil, Paul E, Verplancke, Veronique, Janssens, Annelies, Jacob, Joseph, Pakzad, Ashkan, Conlon, Thomas M, Guvenc, Guney, Yildirim, Ali Önder, Pauwels, Patrick, Koljenovic, Senada, Kwakkel-Van Erp, Johanna M, Lapperre, Thérèse S
Published in American journal of respiratory and critical care medicine (15.03.2024)
Published in American journal of respiratory and critical care medicine (15.03.2024)
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Activation of the WNT/β-Catenin Pathway Attenuates Experimental Emphysema
KNEIDINGER, Nikolaus, ONDER YILDIRIM, Ali, THEO SCHERMULY, Ralph, EICKELBERG, Oliver, KÖNIGSHOFF, Melanie, CALLEGARI, Jens, TAKENAKA, Shinji, MAGDALENA STEIN, Maria, DUMITRASCU, Rio, BOHIA, Alexander, BRACKE, Ken R, MORTY, Rory E, BRUSSELLE, Guy G
Published in American journal of respiratory and critical care medicine (15.03.2011)
Published in American journal of respiratory and critical care medicine (15.03.2011)
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Ex vivo tissue perturbations coupled to single-cell RNA-seq reveal multilineage cell circuit dynamics in human lung fibrogenesis
Lang, Niklas J, Gote-Schniering, Janine, Porras-Gonzalez, Diana, Yang, Lin, De Sadeleer, Laurens J, Jentzsch, R Christoph, Shitov, Vladimir A, Zhou, Shuhong, Ansari, Meshal, Agami, Ahmed, Mayr, Christoph H, Hooshiar Kashani, Baharak, Chen, Yuexin, Heumos, Lukas, Pestoni, Jeanine C, Molnar, Eszter Sarolta, Geeraerts, Emiel, Anquetil, Vincent, Saniere, Laurent, Wögrath, Melanie, Gerckens, Michael, Lehmann, Mareike, Yildirim, Ali Önder, Hatz, Rudolf, Kneidinger, Nikolaus, Behr, Jürgen, Wuyts, Wim A, Stoleriu, Mircea-Gabriel, Luecken, Malte D, Theis, Fabian J, Burgstaller, Gerald, Schiller, Herbert B
Published in Science translational medicine (06.12.2023)
Published in Science translational medicine (06.12.2023)
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Cathepsin B promotes collagen biosynthesis, which drives bronchiolitis obliterans syndrome
Morrone, Carmela, Smirnova, Natalia F, Jeridi, Aicha, Kneidinger, Nikolaus, Hollauer, Christine, Schupp, Jonas Christian, Kaminski, Naftali, Jenne, Dieter, Eickelberg, Oliver, Yildirim, Ali Önder
Published in The European respiratory journal (01.05.2021)
Published in The European respiratory journal (01.05.2021)
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Journal Article
A drug screen with approved compounds identifies amlexanox as a novel Wnt/β‐catenin activator inducing lung epithelial organoid formation
Costa, Rita, Wagner, Darcy E., Doryab, Ali, De Santis, Martina M., Schorpp, Kenji, Rothenaigner, Ina, Lehmann, Mareike, Baarsma, Hoeke A., Liu, Xueping, Schmid, Otmar, Campillos, Monica, Yildirim, Ali Önder, Hadian, Kamyar, Königshoff, Melanie
Published in British journal of pharmacology (01.10.2021)
Published in British journal of pharmacology (01.10.2021)
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A Drosophila model of cigarette smoke induced COPD identifies Nrf2 signaling as an expedient target for intervention
Prange, Ruben, Thiedmann, Marcus, Bhandari, Anita, Mishra, Neha, Sinha, Anupam, Häsler, Robert, Rosenstiel, Philipp, Uliczka, Karin, Wagner, Christina, Yildirim, Ali Önder, Fink, Christine, Roeder, Thomas
Published in Aging (Albany, NY.) (27.08.2018)
Published in Aging (Albany, NY.) (27.08.2018)
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Journal Article
The composition of cigarette smoke determines inflammatory cell recruitment to the lung in COPD mouse models
John, Gerrit, Kohse, Katrin, Orasche, Jürgen, Reda, Ahmed, Schnelle-Kreis, Jürgen, Zimmermann, Ralf, Schmid, Otmar, Eickelberg, Oliver, Yildirim, Ali Önder
Published in Clinical science (1979) (01.02.2014)
Published in Clinical science (1979) (01.02.2014)
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Free DNA in Cystic Fibrosis Airway Fluids Correlates with Airflow Obstruction
Marcos, Veronica, Zhou-Suckow, Zhe, Önder Yildirim, Ali, Bohla, Alexander, Hector, Andreas, Vitkov, Ljubomir, Krautgartner, Wolf Dietrich, Stoiber, Walter, Griese, Matthias, Eickelberg, Oliver, Mall, Marcus A, Hartl, Dominik
Published in Mediators of Inflammation (01.01.2015)
Published in Mediators of Inflammation (01.01.2015)
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A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes
Kollmus, Heike, Fuchs, Helmut, Lengger, Christoph, Haselimashhadi, Hamed, Bogue, Molly A., Östereicher, Manuela A., Horsch, Marion, Adler, Thure, Aguilar-Pimentel, Juan Antonio, Amarie, Oana Veronica, Becker, Lore, Beckers, Johannes, Calzada-Wack, Julia, Garrett, Lillian, Hans, Wolfgang, Hölter, Sabine M., Klein-Rodewald, Tanja, Maier, Holger, Mayer-Kuckuk, Philipp, Miller, Gregor, Moreth, Kristin, Neff, Frauke, Rathkolb, Birgit, Rácz, Ildikó, Rozman, Jan, Spielmann, Nadine, Treise, Irina, Busch, Dirk, Graw, Jochen, Klopstock, Thomas, Wolf, Eckhard, Wurst, Wolfgang, Yildirim, Ali Önder, Mason, Jeremy, Torres, Arturo, Balling, Rudi, Mehaan, Terry, Gailus-Durner, Valerie, Schughart, Klaus, Hrabě de Angelis, Martin
Published in Mammalian genome (01.02.2020)
Published in Mammalian genome (01.02.2020)
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A transcriptomics-guided drug target discovery strategy identifies receptor ligands for lung regeneration
Wu, Xinhui, Bos, I Sophie T, Conlon, Thomas M, Ansari, Meshal, Verschut, Vicky, van der Koog, Luke, Verkleij, Lars A, D'Ambrosi, Angela, Matveyenko, Aleksey, Schiller, Herbert B, Königshoff, Melanie, Schmidt, Martina, Kistemaker, Loes E M, Yildirim, Ali Önder, Gosens, Reinoud
Published in Science advances (25.03.2022)
Published in Science advances (25.03.2022)
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The effect of multiple outgrowths from bronchial tissue explants on progenitor/stem cell number in primary bronchial epithelial cell cultures from smokers and patients with COPD
Bostancieri, Nuray, Bakir, Kemal, Kul, Seval, Eralp, Ayhan, Kayalar, Ozgecan, Konyalilar, Nur, Rajabi, Hadi, Yuncu, Mehmet, Yildirim, Ali Önder, Bayram, Hasan
Published in Frontiers in medicine (13.10.2023)
Published in Frontiers in medicine (13.10.2023)
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Journal Article
CXCR2 mediates NADPH oxidase-independent neutrophil extracellular trap formation in cystic fibrosis airway inflammation
Koller, Barbara, Wiedenbauer, Eva-Maria, Kormann, Michael, Stoiber, Walter, Yildirim, Ali Önder, Döring, Gerd, Krautgartner, Wolf Dietrich, Rieber, Nikolaus, Griese, Matthias, Marcos, Veronica, Roos, Dirk, Belohradsky, Bernd H, Vitkov, Ljubomir, Eickelberg, Oliver, Zhou, Zhe, Hartl, Dominik, Bohla, Alexander, Mall, Marcus A, Hector, Andreas, Roscher, Adelbert
Published in Nature medicine (01.09.2010)
Published in Nature medicine (01.09.2010)
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Cigarette smoke-induced iBALT mediates macrophage activation in a B cell-dependent manner in COPD
John-Schuster, Gerrit, Hager, Katrin, Conlon, Thomas M, Irmler, Martin, Beckers, Johannes, Eickelberg, Oliver, Yildirim, Ali Önder
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2014)
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2014)
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Journal Article
Breathing-induced stretch enhances the efficacy of an inhaled and orally delivered anti-fibrosis drug in vitro
Doryab, Ali, Heydarian, Motaharehsadat, Yildirim, Ali Önder, Hilgendorff, Anne, Behr, Jürgen, Schmid, Otmar
Published in Journal of drug delivery science and technology (01.04.2023)
Published in Journal of drug delivery science and technology (01.04.2023)
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