Circulating Histones Are Major Mediators of Multiple Organ Dysfunction Syndrome in Acute Critical Illnesses
Cheng, Zhenxing, Abrams, Simon T, Alhamdi, Yasir, Toh, Julien, Yu, Weiping, Wang, Guozheng, Toh, Cheng-Hock
Published in Critical care medicine (01.08.2019)
Published in Critical care medicine (01.08.2019)
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Journal Article
A Novel Assay for Neutrophil Extracellular Trap Formation Independently Predicts Disseminated Intravascular Coagulation and Mortality in Critically Ill Patients
Abrams, Simon T, Morton, Ben, Alhamdi, Yasir, Alsabani, Mohmad, Lane, Steven, Welters, Ingeborg D, Wang, Guozheng, Toh, Cheng-Hock
Published in American journal of respiratory and critical care medicine (01.10.2019)
Published in American journal of respiratory and critical care medicine (01.10.2019)
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Journal Article
Assembly of alternative prothrombinase by extracellular histones initiates and disseminates intravascular coagulation
Abrams, Simon T., Su, Dunhao, Sahraoui, Yasmina, Lin, Ziqi, Cheng, Zhenxing, Nesbitt, Kate, Alhamdi, Yasir, Harrasser, Micaela, Du, Min, Foley, Jonathan H., Lillicrap, David, Wang, Guozheng, Toh, Cheng-Hock
Published in Blood (07.01.2021)
Published in Blood (07.01.2021)
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Journal Article
Histone-Associated Thrombocytopenia in Patients Who Are Critically Ill
Alhamdi, Yasir, Abrams, Simon T, Lane, Steven, Wang, Guozheng, Toh, Cheng-Hock
Published in JAMA : the journal of the American Medical Association (23.02.2016)
Published in JAMA : the journal of the American Medical Association (23.02.2016)
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Journal Article
Circulating Pneumolysin Is a Potent Inducer of Cardiac Injury during Pneumococcal Infection
Alhamdi, Yasir, Neill, Daniel R, Abrams, Simon T, Malak, Hesham A, Yahya, Reham, Barrett-Jolley, Richard, Wang, Guozheng, Kadioglu, Aras, Toh, Cheng-Hock
Published in PLoS pathogens (01.05.2015)
Published in PLoS pathogens (01.05.2015)
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Journal Article
Extracellular Histones Inhibit Complement Activation through Interacting with Complement Component 4
Qaddoori, Yasir, Abrams, Simon T, Mould, Paul, Alhamdi, Yasir, Christmas, Stephen E, Wang, Guozheng, Toh, Cheng-Hock
Published in The Journal of immunology (1950) (15.06.2018)
Published in The Journal of immunology (1950) (15.06.2018)
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Journal Article
Extracellular Histone-Induced Protein Kinase C Alpha Activation and Troponin Phosphorylation Is a Potential Mechanism of Cardiac Contractility Depression in Sepsis
Abrams, Simon T, Alhamdi, Yasir, Zi, Min, Guo, Fengmei, Du, Min, Wang, Guozheng, Cartwright, Elizabeth J, Toh, Cheng-Hock
Published in International journal of molecular sciences (01.02.2023)
Published in International journal of molecular sciences (01.02.2023)
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Journal Article
The paraspecific neutralisation of snake venom induced coagulopathy by antivenoms
Ainsworth, Stuart, Slagboom, Julien, Alomran, Nessrin, Pla, Davinia, Alhamdi, Yasir, King, Sarah I., Bolton, Fiona M. S., Gutiérrez, José María, Vonk, Freek J., Toh, Cheng-Hock, Calvete, Juan J., Kool, Jeroen, Harrison, Robert A., Casewell, Nicholas R.
Published in Communications biology (01.01.2018)
Published in Communications biology (01.01.2018)
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Journal Article
The Importance of Pore-Forming Toxins in Multiple Organ Injury and Dysfunction
Abrams, Simon T, Wang, Lijun, Yong, Jun, Yu, Qian, Du, Min, Alhamdi, Yasir, Cheng, Zhenxing, Dart, Caroline, Lane, Steven, Yu, Weiping, Toh, Cheng-Hock, Wang, Guozheng
Published in Biomedicines (01.12.2022)
Published in Biomedicines (01.12.2022)
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Journal Article
Protective effects of carbon monoxide-releasing molecule-2 on the barrier function of intestinal epithelial cells
Mu, Xinwei, Pan, Chen, Zheng, Shuyun, Alhamdi, Yasir, Sun, Bingwei, Shi, Qiankun, Wang, Xiang, Sun, Zhiwei, Toh, Chenghock, Wang, Guozheng
Published in PloS one (07.08.2014)
Published in PloS one (07.08.2014)
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Journal Article
Role of Coagulation Factor Concentrates in the Operating Room
Toh, Cheng-Hock, Alhamdi, Yasir
Published in European Medical Journal (Chelmsford, England) (13.12.2016)
Published in European Medical Journal (Chelmsford, England) (13.12.2016)
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Journal Article
Circulating Histones Are Major Mediators of Cardiac Injury in Patients With Sepsis
Alhamdi, Yasir, Abrams, Simon T, Cheng, Zhenxing, Jing, Shengjie, Su, Dunhao, Liu, Zhiyong, Lane, Steven, Welters, Ingeborg, Wang, Guozheng, Toh, Cheng-Hock
Published in Critical care medicine (01.10.2015)
Published in Critical care medicine (01.10.2015)
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Journal Article
143 The roles and mechanisms of pore-forming toxins in cardiac injury
Wang, Guozheng, Alhamdi, Yasir, Toh, Cheng-Hock
Published in Heart (British Cardiac Society) (01.06.2017)
Published in Heart (British Cardiac Society) (01.06.2017)
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Journal Article
A Novel Assay of Neutrophil Extracellular Traps (NETs) Formation Independently Predicts DIC and Identifies the Rationale for Anti-IL-8 Therapies
Abrams, Simon Timothy, Morton, Ben, Alhamdi, Yasir, Alsabani, Mohmad, Cheng, Zhenxing, Lane, Steven, Welters, Ingeborg, Wang, Guozheng, Toh, Cheng-Hock
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Circulating Histone Concentrations Differentially Affect the Predominance of Left or Right Ventricular Dysfunction in Critical Illness
Alhamdi, Yasir, Zi, Min, Abrams, Simon T, Liu, Tingting, Su, Dunhao, Welters, Ingeborg, Dutt, Tina, Cartwright, Elizabeth J, Wang, Guozheng, Toh, Cheng-Hock
Published in Critical care medicine (01.05.2016)
Published in Critical care medicine (01.05.2016)
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