The MEK1/2 inhibitor, selumetinib (AZD6244; ARRY-142886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models
Holt, S V, Logié, A, Odedra, R, Heier, A, Heaton, S P, Alferez, D, Davies, B R, Wilkinson, R W, Smith, P D
Published in British journal of cancer (28.02.2012)
Published in British journal of cancer (28.02.2012)
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Journal Article
Progesterone receptor antagonists are potential inhibitors of breast cancer stem cell activity
Alferez, D, Eyre, R, Spence, K, Hayhurst, W, Chresta, C, Sacha, H, Clarke, R
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
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Journal Article
The bone metastatic niche promotes breast cancer stem cell activity via IL-1β-Wnt signalling
Eyre, R, Spence, K, Alferez, D, Santiago-Gomez, A, Hart, C, Simoes, B, Brown, M, Gurney, A, Farnie, G, Clarke, R
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
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Journal Article
471 Inhibiting signalling by erbB receptor tyrosine kinases with AZD8931, a potent reversible small molecule inhibitor, reduces intestinal adenoma formation in the ApcMin/+ mouse model
Alferez, D, Logié, A, Seedhar, P, Poulsom, R, Klinowska, T, Wilkinson, R.W
Published in European journal of cancer supplements (2010)
Published in European journal of cancer supplements (2010)
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Journal Article
Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the ApcMin/+ mouse model of early intestinal cancer
Goodlad, R.A., Ryan, A.J., Wedge, S.R., Pyrah, I.T., Alferez, D., Poulsom, R., Smith, N.R., Mandir, N., Watkins, A.J., Wilkinson, R.W.
Published in Carcinogenesis (New York) (01.10.2006)
Published in Carcinogenesis (New York) (01.10.2006)
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Journal Article
478 - Progesterone receptor antagonists are potential inhibitors of breast cancer stem cell activity
Alferez, D., Eyre, R., Spence, K., Hayhurst, W., Chresta, C., Sacha, H., Clarke, R.
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
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Journal Article
Effects of gravity, hypergravity and microgravity on vestibular neurones of the crab
Fraser, P J, Araujo, R, Alferez, D, Carneiro, M J, Pollard, M
Published in Journal of gravitational physiology (01.07.2004)
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Published in Journal of gravitational physiology (01.07.2004)
Journal Article
Abstract PD2-02: SFX-01 targets Wnt signalling to inhibit stem-like cells in breast cancer patient-derived xenograft tumours
Howell, SJ, Simoes, BM, Alferez, D, Eyre, R, Spence, K, Santiago-Gomez, A, Sarmiento-Castro, A, Tanaka, I, Howat, D, Clarke, RB
Published in Cancer research (Chicago, Ill.) (15.02.2017)
Published in Cancer research (Chicago, Ill.) (15.02.2017)
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Journal Article
328 - The bone metastatic niche promotes breast cancer stem cell activity via IL-1β-Wnt signalling
Eyre, R., Spence, K., Alferez, D., Santiago-Gomez, A., Hart, C., Simoes, B., Brown, M., Gurney, A., Farnie, G., Clarke, R.
Published in European journal of cancer (1990) (01.07.2016)
Published in European journal of cancer (1990) (01.07.2016)
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Journal Article
Abstract P5-05-03: Progesterone receptor antagonists as inhibitors of breast cancer stem cell activity
Alferez, D, Clarke, RB, Cresta, C, Mnene, S, Howell, SJ
Published in Cancer research (Chicago, Ill.) (15.12.2013)
Published in Cancer research (Chicago, Ill.) (15.12.2013)
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Journal Article
The MEKI/2 inhibitor, selumetinib (AZD6244; ARRY-I42886), enhances anti-tumour efficacy when combined with conventional chemotherapeutic agents in human tumour xenograft models
HOLT, S. V, LOGIE, A, ODEDRA, R, HEIER, A, HEATON, S. P, ALFEREZ, D, DAVIES, B. R, WILKINSON, R. W, SMITH, P. D
Published in British journal of cancer (2012)
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Published in British journal of cancer (2012)
Journal Article
Inhibiting vascular endothelial growth factor receptor-2 signaling reduces tumor burden in the Apc super(Min/+) mouse model of early intestinal cancer
Goodlad, R A, Ryan, A J, Wedge, SR, Pyrah, I T, Alferez, D, Poulsom, R, Smith, N R, Mandir, N, Watkins, A J, Wilkinson, R W
Published in Carcinogenesis (New York) (01.10.2006)
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Published in Carcinogenesis (New York) (01.10.2006)
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