MP-08.14: Eradication of osteoblastic and osteolytic skeletal metastases of hormone refractory prostate cancer (mHRPC) after treatment with pegylated trispecific disulfide linked Fv (sdFv) targeting epitopes of EGFR, PTHrP and RANKL conjugated covalently with SATA to vinorelbine tartrate
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713 POSTER Molecularly targeted immunochemotherapeutic formulation (SEVINA) composed of pegylated trispecific disulfide linked Fv (sdFv) targeting epitopes of EGFR, PTHrP and RANKL conjugated covalently with SATA to vinorelbine eradicated osteolytic metastases of multiple myeloma inhibiting proliferation of tumor associated and bone microvascular endothelial cells inducing ADCC, AMP and type I, II, III PCD
Giannios, J, Michailakis, E, Alexandropulos, N
Published in European journal of cancer supplements (2007)
Published in European journal of cancer supplements (2007)
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Pegylated liposomal anti-eIF3c shRNA-vinorelbine tartrate formulation (SEVINA-V) inhibits oncogenic protein translational initiation, and oncogene addiction inducing PCD type I, II, and III in NSCLC chemoresistant to taxanes
Giannios, J., Michailakis, E., Alexandropulos, N., Kanellopoulos, A.
Published in Journal of clinical oncology (20.05.2008)
Published in Journal of clinical oncology (20.05.2008)
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Diabody vinorelbine conjugate (DVC) composed of vinorelbine-tartrate conjugated to anti-DNMT1/SHH di-diabody induce ADCC, CDC, AMP and inhibit DNA methylation
John, G. N., Giannios, J., Seraj, E., Kanelopulos, G., Ginopulos, P., Alexandropulos, N.
Published in Journal of clinical oncology (20.06.2007)
Published in Journal of clinical oncology (20.06.2007)
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307 POSTER Neoadjuvant treatment for breast cancer with vinorelbine-tartrate inhibits angiogenesis, lymphangiogenesis and oncogenesis while it upregulates tumor suppressor genes, antilymphangiogenic and antiangiogenic genes inhibiting micrometastases following surgical resection of the primary tumor
Giannios, J., Lambrinos, P., Ginopulos, P., Alexandropulos, N.
Published in European journal of surgical oncology (01.11.2006)
Published in European journal of surgical oncology (01.11.2006)
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338 POSTER Carcinoma of the Ampulla of Vater with CIMP+ after treatment with pegylated liposomal based formulation of Ras siRNA combined with vinorelbine-tartrate exhibited inhibition of Raf/MEK/ERK, PI3K/AKT, DNA methylation and re-expression of tumor suppressor genes inducing type I, II, III PCD
Giannios, J., Lambrinos, P., Alexandropulos, N., Ginopulos, P.
Published in European journal of cancer supplements (01.11.2006)
Published in European journal of cancer supplements (01.11.2006)
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Journal Article