An updated histological classification system for multiple sclerosis lesions
Kuhlmann, Tanja, Ludwin, Samuel, Prat, Alexandre, Antel, Jack, Brück, Wolfgang, Lassmann, Hans
Published in Acta neuropathologica (01.01.2017)
Published in Acta neuropathologica (01.01.2017)
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Journal Article
How do immune cells support and shape the brain in health, disease, and aging?
Schwartz, Michal, Kipnis, Jonathan, Rivest, Serge, Prat, Alexandre
Published in The Journal of neuroscience (06.11.2013)
Published in The Journal of neuroscience (06.11.2013)
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Journal Article
Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology?
Larochelle, Catherine, Uphaus, Timo, Prat, Alexandre, Zipp, Frauke
Published in Trends in neurosciences (Regular ed.) (01.05.2016)
Published in Trends in neurosciences (Regular ed.) (01.05.2016)
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Journal Article
Disruption of central nervous system barriers in multiple sclerosis
Alvarez, Jorge Ivan, Cayrol, Romain, Prat, Alexandre
Published in Biochimica et biophysica acta (01.02.2011)
Published in Biochimica et biophysica acta (01.02.2011)
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Journal Article
Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia
Dong, Yifei, D’Mello, Charlotte, Pinsky, William, Lozinski, Brian M., Kaushik, Deepak K., Ghorbani, Samira, Moezzi, Dorsa, Brown, Dennis, Melo, Francisca C., Zandee, Stephanie, Vo, Tina, Prat, Alexandre, Whitehead, Shawn N., Yong, V. Wee
Published in Nature neuroscience (01.04.2021)
Published in Nature neuroscience (01.04.2021)
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Journal Article
Type I interferons and microbial metabolites of tryptophan modulate astrocyte activity and central nervous system inflammation via the aryl hydrocarbon receptor
Rothhammer, Veit, Mascanfroni, Ivan D, Bunse, Lukas, Takenaka, Maisa C, Kenison, Jessica E, Mayo, Lior, Chao, Chun-Cheih, Patel, Bonny, Yan, Raymond, Blain, Manon, Alvarez, Jorge I, Kébir, Hania, Anandasabapathy, Niroshana, Izquierdo, Guillermo, Jung, Steffen, Obholzer, Nikolaus, Pochet, Nathalie, Clish, Clary B, Prinz, Marco, Prat, Alexandre, Antel, Jack, Quintana, Francisco J
Published in Nature medicine (01.06.2016)
Published in Nature medicine (01.06.2016)
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Journal Article
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39
Takenaka, Maisa C., Gabriely, Galina, Rothhammer, Veit, Mascanfroni, Ivan D., Wheeler, Michael A., Chao, Chun-Cheih, Gutiérrez-Vázquez, Cristina, Kenison, Jessica, Tjon, Emily C., Barroso, Andreia, Vandeventer, Tyler, de Lima, Kalil Alves, Rothweiler, Sonja, Mayo, Lior, Ghannam, Soufiene, Zandee, Stephanie, Healy, Luke, Sherr, David, Farez, Mauricio F., Prat, Alexandre, Antel, Jack, Reardon, David A., Zhang, Hailei, Robson, Simon C., Getz, Gad, Weiner, Howard L., Quintana, Francisco J.
Published in Nature neuroscience (01.05.2019)
Published in Nature neuroscience (01.05.2019)
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Journal Article
Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study
He, Anna, Merkel, Bernd, Brown, James William L, Zhovits Ryerson, Lana, Kister, Ilya, Malpas, Charles B, Sharmin, Sifat, Horakova, Dana, Kubala Havrdova, Eva, Spelman, Tim, Izquierdo, Guillermo, Eichau, Sara, Trojano, Maria, Lugaresi, Alessandra, Hupperts, Raymond, Sola, Patrizia, Ferraro, Diana, Lycke, Jan, Grand'Maison, Francois, Prat, Alexandre, Girard, Marc, Duquette, Pierre, Larochelle, Catherine, Svenningsson, Anders, Petersen, Thor, Grammond, Pierre, Granella, Franco, Van Pesch, Vincent, Bergamaschi, Roberto, McGuigan, Christopher, Coles, Alasdair, Hillert, Jan, Piehl, Fredrik, Butzkueven, Helmut, Kalincik, Tomas
Published in Lancet neurology (01.04.2020)
Published in Lancet neurology (01.04.2020)
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Journal Article
Proinflammatory GM-CSF-producing B cells in multiple sclerosis and B cell depletion therapy
Li, Rui, Rezk, Ayman, Miyazaki, Yusei, Hilgenberg, Ellen, Touil, Hanane, Shen, Ping, Moore, Craig S, Michel, Laure, Althekair, Faisal, Rajasekharan, Sathy, Gommerman, Jennifer L, Prat, Alexandre, Fillatreau, Simon, Bar-Or, Amit
Published in Science translational medicine (21.10.2015)
Published in Science translational medicine (21.10.2015)
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Journal Article
Overcoming the Brain Barriers: From Immune Cells to Nanoparticles
Charabati, Marc, Rabanel, Jean-Michel, Ramassamy, Charles, Prat, Alexandre
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2020)
Published in Trends in pharmacological sciences (Regular ed.) (01.01.2020)
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Journal Article
Frailty in ageing persons with multiple sclerosis
Ayrignac, Xavier, Larochelle, Catherine, Keezer, Mark, Roger, Elaine, Poirier, Josée, Lahav, Boaz, Girard, Marc, Prat, Alexandre, Duquette, Pierre
Published in Multiple sclerosis (01.04.2021)
Published in Multiple sclerosis (01.04.2021)
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Journal Article
Regulation of astrocyte activation by glycolipids drives chronic CNS inflammation
Mayo, Lior, Trauger, Sunia A, Blain, Manon, Nadeau, Meghan, Patel, Bonny, Alvarez, Jorge I, Mascanfroni, Ivan D, Yeste, Ada, Kivisäkk, Pia, Kallas, Keith, Ellezam, Benjamin, Bakshi, Rohit, Prat, Alexandre, Antel, Jack P, Weiner, Howard L, Quintana, Francisco J
Published in Nature medicine (01.10.2014)
Published in Nature medicine (01.10.2014)
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Journal Article
Metabolic Control of Astrocyte Pathogenic Activity via cPLA2-MAVS
Chao, Chun-Cheih, Gutiérrez-Vázquez, Cristina, Rothhammer, Veit, Mayo, Lior, Wheeler, Michael A., Tjon, Emily C., Zandee, Stephanie E.J., Blain, Manon, de Lima, Kalil Alves, Takenaka, Maisa C., Avila-Pacheco, Julian, Hewson, Patrick, Liu, Lei, Sanmarco, Liliana M., Borucki, Davis M., Lipof, Gabriel Z., Trauger, Sunia A., Clish, Clary B., Antel, Jack P., Prat, Alexandre, Quintana, Francisco J.
Published in Cell (12.12.2019)
Published in Cell (12.12.2019)
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Journal Article
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
Alvarez, Jorge Ivan, Dodelet-Devillers, Aurore, Kebir, Hania, Ifergan, Igal, Fabre, Pierre J., Terouz, Simone, Sabbagh, Mike, Wosik, Karolina, Bourbonnière, Lyne, Bernard, Monique, van Horssen, Jack, de Vries, Helga E., Charron, Frédéric, Prat, Alexandre
Published in Science (American Association for the Advancement of Science) (23.12.2011)
Published in Science (American Association for the Advancement of Science) (23.12.2011)
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Journal Article
Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis
Sánchez-Fernández, Alba, Zandee, Stephanie, Mastrogiovanni, Mauricio, Charabati, Marc, Rubbo, Homero, Prat, Alexandre, López-Vales, Rubèn
Published in Journal of neuroinflammation (02.02.2022)
Published in Journal of neuroinflammation (02.02.2022)
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Journal Article
Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology
Derada Troletti, Claudio, Fontijn, Ruud D., Gowing, Elizabeth, Charabati, Marc, van Het Hof, Bert, Didouh, Imad, van der Pol, Susanne M. A., Geerts, Dirk, Prat, Alexandre, van Horssen, Jack, Kooij, Gijs, de Vries, Helga E.
Published in Cell death & disease (18.01.2019)
Published in Cell death & disease (18.01.2019)
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Journal Article
Glial regulation of the blood-brain barrier in health and disease
Broux, Bieke, Gowing, Elizabeth, Prat, Alexandre
Published in Seminars in Immunopathology (01.11.2015)
Published in Seminars in Immunopathology (01.11.2015)
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Book Review