Red blood cell tension protects against severe malaria in the Dantu blood group
Kariuki, Silvia N., Marin-Menendez, Alejandro, Introini, Viola, Ravenhill, Benjamin J., Lin, Yen-Chun, Macharia, Alex, Makale, Johnstone, Tendwa, Metrine, Nyamu, Wilfred, Kotar, Jurij, Carrasquilla, Manuela, Rowe, J. Alexandra, Rockett, Kirk, Kwiatkowski, Dominic, Weekes, Michael P., Cicuta, Pietro, Williams, Thomas N., Rayner, Julian C.
Published in Nature (London) (24.09.2020)
Published in Nature (London) (24.09.2020)
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Dantu Blood Group Erythrocytes Form Large Plasmodium falciparum Rosettes Less Commonly
Carlier, Molly S A, Nyamu, Wilfred, Makale, Johnstone, Williams, Thomas N, Rowe, J Alexandra, Kariuki, Silvia N
Published in The American journal of tropical medicine and hygiene (01.03.2024)
Published in The American journal of tropical medicine and hygiene (01.03.2024)
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Infected erythrocytes expressing DC13 PfEMP1 differ from recombinant proteins in EPCR-binding function
Azasi, Yvonne, Lindergard, Gabriella, Ghumra, Ashfaq, Mu, Jianbing, Miller, Louis H., Rowe, J. Alexandra
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (30.01.2018)
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Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance
Cao, Huan, Antonopoulos, Aristotelis, Henderson, Sadie, Wassall, Heather, Brewin, John, Masson, Alanna, Shepherd, Jenna, Konieczny, Gabriela, Patel, Bhinal, Williams, Maria-Louise, Davie, Adam, Forrester, Megan A., Hall, Lindsay, Minter, Beverley, Tampakis, Dimitris, Moss, Michael, Lennon, Charlotte, Pickford, Wendy, Erwig, Lars, Robertson, Beverley, Dell, Anne, Brown, Gordon D., Wilson, Heather M., Rees, David C., Haslam, Stuart M., Alexandra Rowe, J., Barker, Robert N., Vickers, Mark A.
Published in Nature communications (19.03.2021)
Published in Nature communications (19.03.2021)
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Non-O ABO blood group genotypes differ in their associations with Plasmodium falciparum rosetting and severe malaria
Opi, D Herbert, Ndila, Carolyne M, Uyoga, Sophie, Macharia, Alex W, Fennell, Clare, Ochola, Lucy B, Nyutu, Gideon, Siddondo, Bethseba R, Ojal, John, Shebe, Mohammed, Awuondo, Kennedy O, Mturi, Neema, Peshu, Norbert, Tsofa, Benjamin, Band, Gavin, Maitland, Kathryn, Kwiatkowski, Dominic P, Rockett, Kirk A, Williams, Thomas N, Rowe, J Alexandra
Published in PLoS genetics (14.09.2023)
Published in PLoS genetics (14.09.2023)
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Complement C1s cleaves PfEMP1 at interdomain conserved sites inhibiting Plasmodium falciparum cytoadherence
Azasi, Yvonne, Low, Leanne M., Just, Ashley N., Raghavan, Sai S. R., Wang, Christian W., Valenzuela-Leon, Paola, Rowe, J. Alexandra, Smith, Joseph D., Lavstsen, Thomas, Turner, Louise, Calvo, Eric, Miller, Louis H.
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.2021)
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.2021)
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A subset of group A-like var genes encodes the malaria parasite ligands for binding to human brain endothelial cells
Claessens, Antoine, Adams, Yvonne, Ghumra, Ashfaq, Lindergard, Gabriella, Buchan, Caitlin C, Andisi, Cheryl, Bull, Peter C, Mok, Sachel, Gupta, Archna P, Wang, Christian W, Turner, Louise, Arman, Mònica, Raza, Ahmed, Bozdech, Zbynek, Rowe, J Alexandra
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (26.06.2012)
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Rosetting Plasmodium falciparum-Infected Erythrocytes Bind to Human Brain Microvascular Endothelial Cells In Vitro, Demonstrating a Dual Adhesion Phenotype Mediated by Distinct P. falciparum Erythrocyte Membrane Protein 1 Domains
Adams, Yvonne, Kuhnrae, Pongsak, Higgins, Matthew K, Ghumra, Ashfaq, Rowe, J Alexandra
Published in Infection and Immunity (01.03.2014)
Published in Infection and Immunity (01.03.2014)
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Mapping immune variation and var gene switching in naive hosts infected with Plasmodium falciparum
Milne, Kathryn, Ivens, Alasdair, Reid, Adam J, Lotkowska, Magda E, O'Toole, Aine, Sankaranarayanan, Geetha, Munoz Sandoval, Diana, Nahrendorf, Wiebke, Regnault, Clement, Edwards, Nick J, Silk, Sarah E, Payne, Ruth O, Minassian, Angela M, Venkatraman, Navin, Sanders, Mandy J, Hill, Adrian Vs, Barrett, Michael, Berriman, Matthew, Draper, Simon J, Rowe, J Alexandra, Spence, Philip J
Published in eLife (02.03.2021)
Published in eLife (02.03.2021)
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Blood group O protects against severe Plasmodium falciparum malaria through the mechanism of reduced rosetting
Rowe, J. Alexandra, Handel, Ian G, Thera, Mahamadou A, Deans, Anne-Marie, Lyke, Kirsten E, Koné, Abdoulaye, Diallo, Dapa A, Raza, Ahmed, Kai, Oscar, Marsh, Kevin, Plowe, Christopher V, Doumbo, Ogobara K, Moulds, Joann M
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (30.10.2007)
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Induction of strain-transcending antibodies against Group A PfEMP1 surface antigens from virulent malaria parasites
Ghumra, Ashfaq, Semblat, Jean-Philippe, Ataide, Ricardo, Kifude, Carolyne, Adams, Yvonne, Claessens, Antoine, Anong, Damian N, Bull, Peter C, Fennell, Clare, Arman, Monica, Amambua-Ngwa, Alfred, Walther, Michael, Conway, David J, Kassambara, Lalla, Doumbo, Ogobara K, Raza, Ahmed, Rowe, J Alexandra
Published in PLoS pathogens (01.04.2012)
Published in PLoS pathogens (01.04.2012)
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Two complement receptor one alleles have opposing associations with cerebral malaria and interact with α + thalassaemia
Opi, D Herbert, Swann, Olivia, Macharia, Alexander, Uyoga, Sophie, Band, Gavin, Ndila, Carolyne M, Harrison, Ewen M, Thera, Mahamadou A, Kone, Abdoulaye K, Diallo, Dapa A, Doumbo, Ogobara K, Lyke, Kirsten E, Plowe, Christopher V, Moulds, Joann M, Shebbe, Mohammed, Mturi, Neema, Peshu, Norbert, Maitland, Kathryn, Raza, Ahmed, Kwiatkowski, Dominic P, Rockett, Kirk A, Williams, Thomas N, Rowe, J Alexandra
Published in eLife (25.04.2018)
Published in eLife (25.04.2018)
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Immunisation with recombinant PfEMP1 domains elicits functional rosette-inhibiting and phagocytosis-inducing antibodies to Plasmodium falciparum
Ghumra, Ashfaq, Khunrae, Pongsak, Ataide, Ricardo, Raza, Ahmed, Rogerson, Stephen J, Higgins, Matthew K, Rowe, J Alexandra
Published in PloS one (31.01.2011)
Published in PloS one (31.01.2011)
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High Levels of Plasmodium falciparum Rosetting in All Clinical Forms of Severe Malaria in African Children
Doumbo, Ogobara K, Thera, Mahamadou A, Kone, Abdoulaye K, Raza, Ahmed, Tempest, Louisa J, Lyke, Kirsten E, Plowe, Christopher V, Rowe, J. Alexandra
Published in The American journal of tropical medicine and hygiene (01.12.2009)
Published in The American journal of tropical medicine and hygiene (01.12.2009)
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Virulence of Malaria Is Associated with Differential Expression of Plasmodium falciparum var Gene Subgroups in a Case-Control Study
Kaestli, Mirjam, Cockburn, Ian A., Cortés, Alfred, Baea, Kay, Rowe, J. Alexandra, Beck, Hans-Peter
Published in The Journal of infectious diseases (01.06.2006)
Published in The Journal of infectious diseases (01.06.2006)
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Seroreactivity to Plasmodium falciparum Erythrocyte Membrane Protein 1 Intracellular Domain in Malaria-Exposed Children and Adults
Travassos, Mark A., Niangaly, Amadou, Bailey, Jason A., Ouattara, Amed, Coulibaly, Drissa, Laurens, Matthew B., Pablo, Jozelyn, Jasinskas, Algis, Nakajima-Sasaki, Rie, Berry, Andrea A., Takala-Harrison, Shannon, Kouriba, Bourema, Rowe, J. Alexandra, Lyke, Kirsten E., Doumbo, Ogobara K., Thera, Mahamadou A., Felgner, Philip L., Plowe, Christopher V.
Published in The Journal of infectious diseases (01.11.2013)
Published in The Journal of infectious diseases (01.11.2013)
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