Complexes of Trypanosoma cruzi sterol 14α-demethylase (CYP51) with two pyridine-based drug candidates for Chagas disease: structural basis for pathogen selectivity
Hargrove, Tatiana Y, Wawrzak, Zdzislaw, Alexander, Paul W, Chaplin, Jason H, Keenan, Martine, Charman, Susan A, Perez, Catherine J, Waterman, Michael R, Chatelain, Eric, Lepesheva, Galina I
Published in The Journal of biological chemistry (01.11.2013)
Published in The Journal of biological chemistry (01.11.2013)
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Analogues of Fenarimol Are Potent Inhibitors of Trypanosoma cruzi and Are Efficacious in a Murine Model of Chagas Disease
Keenan, Martine, Abbott, Michael J, Alexander, Paul W, Armstrong, Tanya, Best, Wayne M, Berven, Bradley, Botero, Adriana, Chaplin, Jason H, Charman, Susan A, Chatelain, Eric, von Geldern, Thomas W, Kerfoot, Maria, Khong, Andrea, Nguyen, Tien, McManus, Joshua D, Morizzi, Julia, Ryan, Eileen, Scandale, Ivan, Thompson, R. Andrew, Wang, Sen Z, White, Karen L
Published in Journal of medicinal chemistry (10.05.2012)
Published in Journal of medicinal chemistry (10.05.2012)
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Two Analogues of Fenarimol Show Curative Activity in an Experimental Model of Chagas Disease
Keenan, Martine, Chaplin, Jason H, Alexander, Paul W, Abbott, Michael J, Best, Wayne M, Khong, Andrea, Botero, Adriana, Perez, Catherine, Cornwall, Scott, Thompson, R. Andrew, White, Karen L, Shackleford, David M, Koltun, Maria, Chiu, Francis C. K, Morizzi, Julia, Ryan, Eileen, Campbell, Michael, von Geldern, Thomas W, Scandale, Ivan, Chatelain, Eric, Charman, Susan A
Published in Journal of medicinal chemistry (27.12.2013)
Published in Journal of medicinal chemistry (27.12.2013)
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Design, structure–activity relationship and in vivo efficacy of piperazine analogues of fenarimol as inhibitors of Trypanosoma cruzi
Keenan, Martine, Alexander, Paul W., Diao, Hugo, Best, Wayne M., Khong, Andrea, Kerfoot, Maria, Thompson, R. C. Andrew, White, Karen L., Shackleford, David M., Ryan, Eileen, Gregg, Alison D., Charman, Susan A., von Geldern, Thomas W., Scandale, Ivan, Chatelain, Eric
Published in Bioorganic & medicinal chemistry (01.04.2013)
Published in Bioorganic & medicinal chemistry (01.04.2013)
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Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi
Keenan, Martine, Alexander, Paul W, Chaplin, Jason H, Abbott, Michael J, Diao, Hugo, Wang, Zhisen, Best, Wayne M, Perez, Catherine J, Cornwall, Scott M J, Keatley, Sarah K, Thompson, R C Andrew, Charman, Susan A, White, Karen L, Ryan, Eileen, Chen, Gong, Ioset, Jean-Robert, von Geldern, Thomas W, Chatelain, Eric
Published in Future medicinal chemistry (01.10.2013)
Published in Future medicinal chemistry (01.10.2013)
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DEPP functionally graded piezoceramics via micro-fabrication by co-extrusion
ALEXANDER, Paul W, BREI, Diann, HALLORAN, John W
Published in Journal of materials science (01.07.2007)
Published in Journal of materials science (01.07.2007)
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Fabrication and experimental characterization of d31 telescopic piezoelectric actuators
ALEXANDER, Paul W, BREI, Diann, WEIGUO MIAO, HALLORAN, John W, GENTILMAN, Richard L, SCHMIDT, Gerald E, MCGUIRE, Patrick T, HOLLENBECK, John R
Published in Journal of materials science (01.09.2001)
Published in Journal of materials science (01.09.2001)
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Complexes of Trypanosoma cruzi Sterol 14α-Demethylase (CYP51) with Two Pyridine-based Drug Candidates for Chagas Disease
Hargrove, Tatiana Y., Wawrzak, Zdzislaw, Alexander, Paul W., Chaplin, Jason H., Keenan, Martine, Charman, Susan A., Perez, Catherine J., Waterman, Michael R., Chatelain, Eric, Lepesheva, Galina I.
Published in The Journal of biological chemistry (01.11.2013)
Published in The Journal of biological chemistry (01.11.2013)
Get full text
Journal Article