Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders
Cisar, Justin S, Weber, Olivia D, Clapper, Jason R, Blankman, Jacqueline L, Henry, Cassandra L, Simon, Gabriel M, Alexander, Jessica P, Jones, Todd K, Ezekowitz, R. Alan B, O’Neill, Gary P, Grice, Cheryl A
Published in Journal of medicinal chemistry (25.10.2018)
Published in Journal of medicinal chemistry (25.10.2018)
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The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors
Marrs, William R, Blankman, Jacqueline L, Horne, Eric A, Thomazeau, Aurore, Lin, Yi Hsing, Coy, Jonathan, Bodor, Agnes L, Muccioli, Giulio G, Hu, Sherry Shu-Jung, Woodruff, Grace, Fung, Susan, Lafourcade, Mathieu, Alexander, Jessica P, Long, Jonathan Z, Li, Weiwei, Xu, Cong, Möller, Thomas, Mackie, Ken, Manzoni, Olivier J, Cravatt, Benjamin F, Stella, Nephi
Published in Nature neuroscience (01.08.2010)
Published in Nature neuroscience (01.08.2010)
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Conversion of Acetaminophen to the Bioactive N-Acylphenolamine AM404 via Fatty Acid Amide Hydrolase-dependent Arachidonic Acid Conjugation in the Nervous System
Högestätt, Edward D., Jönsson, Bo A.G., Ermund, Anna, Andersson, David A., Björk, Henrik, Alexander, Jessica P., Cravatt, Benjamin F., Basbaum, Allan I., Zygmunt, Peter M.
Published in The Journal of biological chemistry (09.09.2005)
Published in The Journal of biological chemistry (09.09.2005)
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Novel Mechanistic Class of Fatty Acid Amide Hydrolase Inhibitors with Remarkable Selectivity
Ahn, Kyunghye, Johnson, Douglas S, Fitzgerald, Laura R, Liimatta, Marya, Arendse, Andrea, Stevenson, Tracy, Lund, Eric. T, Nugent, Richard A, Nomanbhoy, Tyzoon K, Alexander, Jessica P, Cravatt, Benjamin F
Published in Biochemistry (Easton) (13.11.2007)
Published in Biochemistry (Easton) (13.11.2007)
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Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators
Clapper, Jason R, Henry, Cassandra L, Niphakis, Micah J, Knize, Anna M, Coppola, Aundrea R, Simon, Gabriel M, Ngo, Nhi, Herbst, Rachel A, Herbst, Dylan M, Reed, Alex W, Cisar, Justin S, Weber, Olivia D, Viader, Andreu, Alexander, Jessica P, Cunningham, Mark L, Jones, Todd K, Fraser, Iain P, Grice, Cheryl A, Ezekowitz, R Alan B, O'Neill, Gary P, Blankman, Jacqueline L
Published in The Journal of pharmacology and experimental therapeutics (01.12.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2018)
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Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction
Moy, Lily Y, Jia, Yanlin, Caniga, Michael, Lieber, Gissela, Gil, Malgorzata, Fernandez, Xiomara, Sirkowski, Erich, Miller, Richard, Alexander, Jessica P, Lee, Hyun-Hee, Shin, John D, Ellis, J Michael, Chen, Hongmin, Wilhelm, Alan, Yu, Hongshi, Vincent, Stella, Chapman, Richard W, Kelly, Nancy, Hickey, Emily, Abraham, William M, Northrup, Alan, Miller, Thomas, Houshyar, Hani, Crackower, Michael A
Published in American journal of respiratory cell and molecular biology (01.12.2013)
Published in American journal of respiratory cell and molecular biology (01.12.2013)
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Discovery of MK-4409, a Novel Oxazole FAAH Inhibitor for the Treatment of Inflammatory and Neuropathic Pain
Chobanian, Harry R, Guo, Yan, Liu, Ping, Chioda, Marc D, Fung, Selena, Lanza, Thomas J, Chang, Linda, Bakshi, Raman K, Dellureficio, James P, Hong, Qingmei, McLaughlin, Mark, Belyk, Kevin M, Krska, Shane W, Makarewicz, Amanda K, Martel, Elliot J, Leone, Joseph F, Frey, Lisa, Karanam, Bindhu, Madeira, Maria, Alvaro, Raul, Shuman, Joyce, Salituro, Gino, Terebetski, Jenna L, Jochnowitz, Nina, Mistry, Shruti, McGowan, Erin, Hajdu, Richard, Rosenbach, Mark, Abbadie, Catherine, Alexander, Jessica P, Shiao, Lin-Lin, Sullivan, Kathleen M, Nargund, Ravi P, Wyvratt, Matthew J, Lin, Linus S, DeVita, Robert J
Published in ACS medicinal chemistry letters (12.06.2014)
Published in ACS medicinal chemistry letters (12.06.2014)
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γ-Glutamyl Hydrolase: Kinetic Characterization of Isopeptide Hydrolysis Using Fluorogenic Substrates
Alexander, Jessica P, Ryan, Thomas J, Ballou, David P, Coward, James K
Published in Biochemistry (Easton) (29.01.2008)
Published in Biochemistry (Easton) (29.01.2008)
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Conversion of acetaminophen to the bioactive N-acyl phenolamine AM404 via fatty acid amide hydrolase-dependent arachidonic acid conjugation in the nervous system
Högestätt, Edward, Jönsson, Bo A, Ermund, Anna, Andersson, David, Björk, Henrik, Alexander, Jessica P, Cravatt, Benjamin F, Basbaum, Allan I, Zygmunt, Peter
Published in The Journal of biological chemistry (2005)
Published in The Journal of biological chemistry (2005)
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