Current state and future prospects of artificial intelligence in ophthalmology: a review
Hogarty, Daniel T, Mackey, David A, Hewitt, Alex W
Published in Clinical & experimental ophthalmology (01.01.2019)
Published in Clinical & experimental ophthalmology (01.01.2019)
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Single-cell eQTL mapping identifies cell type-specific genetic control of autoimmune disease
Yazar, Seyhan, Alquicira-Hernandez, Jose, Wing, Kristof, Senabouth, Anne, Gordon, M Grace, Andersen, Stacey, Lu, Qinyi, Rowson, Antonia, Taylor, Thomas R P, Clarke, Linda, Maccora, Katia, Chen, Christine, Cook, Anthony L, Ye, Chun Jimmie, Fairfax, Kirsten A, Hewitt, Alex W, Powell, Joseph E
Published in Science (American Association for the Advancement of Science) (08.04.2022)
Published in Science (American Association for the Advancement of Science) (08.04.2022)
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Meta-analysis of 542,934 subjects of European ancestry identifies new genes and mechanisms predisposing to refractive error and myopia
Hysi, Pirro G., Choquet, Hélène, Khawaja, Anthony P., Wojciechowski, Robert, Tedja, Milly S., Yin, Jie, Simcoe, Mark J., Patasova, Karina, Mahroo, Omar A., Thai, Khanh K., Cumberland, Phillippa M., Melles, Ronald B., Verhoeven, Virginie J. M., Vitart, Veronique, Segre, Ayellet, Stone, Richard A., Wareham, Nick, Hewitt, Alex W., Mackey, David A., Klaver, Caroline C. W., MacGregor, Stuart, Khaw, Peng T., Foster, Paul J., Guggenheim, Jeremy A., Rahi, Jugnoo S., Jorgenson, Eric, Hammond, Christopher J.
Published in Nature genetics (01.04.2020)
Published in Nature genetics (01.04.2020)
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Gene therapy for visual loss: Opportunities and concerns
Lee, Jia Hui, Wang, Jiang-Hui, Chen, Jinying, Li, Fan, Edwards, Thomas L., Hewitt, Alex W., Liu, Guei-Sheung
Published in Progress in retinal and eye research (01.01.2019)
Published in Progress in retinal and eye research (01.01.2019)
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Journal Article
Genetic risk of glaucoma is associated with vascular and retinal nerve fibre wedge defects
Saks, Danit G., Schulz, Angela, Qassim, Ayub, Marshall, Henry, Hewitt, Alex W., MacGregor, Stuart, Craig, Jamie E., Graham, Stuart L.
Published in Acta ophthalmologica (Oxford, England) (01.03.2024)
Published in Acta ophthalmologica (Oxford, England) (01.03.2024)
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Engineering domain-inlaid SaCas9 adenine base editors with reduced RNA off-targets and increased on-target DNA editing
Nguyen Tran, Minh Thuan, Mohd Khalid, Mohd Khairul Nizam, Wang, Qi, Walker, Jacqueline K. R., Lidgerwood, Grace E., Dilworth, Kimberley L., Lisowski, Leszek, Pébay, Alice, Hewitt, Alex W.
Published in Nature communications (25.09.2020)
Published in Nature communications (25.09.2020)
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Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma
MacGregor, Stuart, Ong, Jue-Sheng, An, Jiyuan, Han, Xikun, Zhou, Tiger, Siggs, Owen M., Law, Matthew H., Souzeau, Emmanuelle, Sharma, Shiwani, Lynn, David J., Beesley, Jonathan, Sheldrick, Bronwyn, Mills, Richard A., Landers, John, Ruddle, Jonathan B., Graham, Stuart L., Healey, Paul R., White, Andrew J. R., Casson, Robert J., Best, Stephen, Grigg, John R, Goldberg, Ivan, Powell, Joseph E., Whiteman, David C., Radford-Smith, Graham L., Martin, Nicholas G., Montgomery, Grant W., Burdon, Kathryn P., Mackey, David A., Gharahkhani, Puya, Craig, Jamie E., Hewitt, Alex W.
Published in Nature genetics (01.08.2018)
Published in Nature genetics (01.08.2018)
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Using Mendelian randomization to evaluate the causal relationship between serum C-reactive protein levels and age-related macular degeneration
Han, Xikun, Ong, Jue-Sheng, An, Jiyuan, Hewitt, Alex W., Gharahkhani, Puya, MacGregor, Stuart
Published in European journal of epidemiology (01.02.2020)
Published in European journal of epidemiology (01.02.2020)
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Measurement of Systemic Mitochondrial Function in Advanced Primary Open-Angle Glaucoma and Leber Hereditary Optic Neuropathy
Van Bergen, Nicole J, Crowston, Jonathan G, Craig, Jamie E, Burdon, Kathryn P, Kearns, Lisa S, Sharma, Shiwani, Hewitt, Alex W, Mackey, David A, Trounce, Ian A
Published in PloS one (23.10.2015)
Published in PloS one (23.10.2015)
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Approach for in vivo delivery of CRISPR/Cas system: a recent update and future prospect
Chuang, Yu-Fan, Phipps, Andrew J., Lin, Fan-Li, Hecht, Valerie, Hewitt, Alex W., Wang, Peng-Yuan, Liu, Guei-Sheung
Published in Cellular and molecular life sciences : CMLS (01.03.2021)
Published in Cellular and molecular life sciences : CMLS (01.03.2021)
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Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells
Neavin, Drew, Nguyen, Quan, Daniszewski, Maciej S, Liang, Helena H, Chiu, Han Sheng, Wee, Yong Kiat, Senabouth, Anne, Lukowski, Samuel W, Crombie, Duncan E, Lidgerwood, Grace E, Hernández, Damián, Vickers, James C, Cook, Anthony L, Palpant, Nathan J, Pébay, Alice, Hewitt, Alex W, Powell, Joseph E
Published in Genome Biology (05.03.2021)
Published in Genome Biology (05.03.2021)
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Corneal Stiffness Parameters Are Predictive of Structural and Functional Progression in Glaucoma Suspect Eyes
Qassim, Ayub, Mullany, Sean, Abedi, Farshad, Marshall, Henry, Hassall, Mark M., Kolovos, Antonia, Knight, Lachlan S.W., Nguyen, Thi, Awadalla, Mona S., Chappell, Angela, Schulz, Angela M., Galanopoulos, Anna, Agar, Ashish, Healey, Paul R., Hewitt, Alex W., Graham, Stuart L., Landers, John, Casson, Robert J., Siggs, Owen M., Craig, Jamie E.
Published in Ophthalmology (Rochester, Minn.) (01.07.2021)
Published in Ophthalmology (Rochester, Minn.) (01.07.2021)
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Drusen in patient-derived hiPSC-RPE models of macular dystrophies
Galloway, Chad A., Dalvi, Sonal, Hung, Sandy S. C., MacDonald, Leslie A., Latchney, Lisa R., Wong, Raymond C. B., Guymer, Robyn H., Mackey, David A., Williams, David S., Chung, Mina M., Gamm, David M., Pébay, Alice, Hewitt, Alex W., Singh, Ruchira
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (26.09.2017)
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Genotype-free demultiplexing of pooled single-cell RNA-seq
Xu, Jun, Falconer, Caitlin, Nguyen, Quan, Crawford, Joanna, McKinnon, Brett D, Mortlock, Sally, Senabouth, Anne, Andersen, Stacey, Chiu, Han Sheng, Jiang, Longda, Palpant, Nathan J, Yang, Jian, Mueller, Michael D, Hewitt, Alex W, Pébay, Alice, Montgomery, Grant W, Powell, Joseph E, Coin, Lachlan J M
Published in Genome Biology (19.12.2019)
Published in Genome Biology (19.12.2019)
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Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1
Burdon, Kathryn P, Macgregor, Stuart, Hewitt, Alex W, Sharma, Shiwani, Chidlow, Glyn, Mills, Richard A, Danoy, Patrick, Casson, Robert, Viswanathan, Ananth C, Liu, Jimmy Z, Landers, John, Henders, Anjali K, Wood, John, Souzeau, Emmanuelle, Crawford, April, Leo, Paul, Wang, Jie Jin, Rochtchina, Elena, Nyholt, Dale R, Martin, Nicholas G, Montgomery, Grant W, Mitchell, Paul, Brown, Matthew A, Mackey, David A, Craig, Jamie E
Published in Nature genetics (01.06.2011)
Published in Nature genetics (01.06.2011)
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Journal Article
A Systematic Meta-Analysis of Genetic Association Studies for Diabetic Retinopathy
ABHARY, Sotoodeh, HEWITT, Alex W, BURDON, Kathryn P, CRAIG, Jamie E
Published in Diabetes (New York, N.Y.) (01.09.2009)
Published in Diabetes (New York, N.Y.) (01.09.2009)
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Journal Article
Giant cell arteritis: ophthalmic manifestations of a systemic disease
De Smit, Elisabeth, O’Sullivan, Eoin, Mackey, David A., Hewitt, Alex W.
Published in Graefe's Archive for Clinical and Experimental Ophthalmology (01.12.2016)
Published in Graefe's Archive for Clinical and Experimental Ophthalmology (01.12.2016)
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Journal Article
Book Review
AAV-Mediated CRISPR/Cas Gene Editing of Retinal Cells In Vivo
Hung, Sandy S C, Chrysostomou, Vicki, Li, Fan, Lim, Jeremiah K H, Wang, Jiang-Hui, Powell, Joseph E, Tu, Leilei, Daniszewski, Maciej, Lo, Camden, Wong, Raymond C, Crowston, Jonathan G, Pébay, Alice, King, Anna E, Bui, Bang V, Liu, Guei-Sheung, Hewitt, Alex W
Published in Investigative ophthalmology & visual science (01.06.2016)
Published in Investigative ophthalmology & visual science (01.06.2016)
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