Synthetic Strategies toward SGLT2 Inhibitors
Aguillón, Anderson R, Mascarello, Alessandra, Segretti, Natanael D, de Azevedo, Hatylas F. Z, Guimaraes, Cristiano R. W, Miranda, Leandro S. M, de Souza, Rodrigo O. M. A
Published in Organic process research & development (20.04.2018)
Published in Organic process research & development (20.04.2018)
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Journal Article
Discovery of Mycobacterium tuberculosis protein tyrosine phosphatase B (PtpB) inhibitors from natural products
Mascarello, Alessandra, Mori, Mattia, Chiaradia-Delatorre, Louise Domeneghini, Menegatti, Angela Camila Orbem, Delle Monache, Franco, Ferrari, Franco, Yunes, Rosendo Augusto, Nunes, Ricardo José, Terenzi, Hernán, Botta, Bruno, Botta, Maurizio
Published in PloS one (14.10.2013)
Published in PloS one (14.10.2013)
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Journal Article
Mycobacterium tuberculosis-Secreted Tyrosine Phosphatases as Targets Against Tuberculosis: Exploring Natural Sources in Searching for New Drugs
Mascarello, Alessandra, Chiaradia-Delatorre, Louise Domeneghini, Mori, Mattia, Terenzi, Hernán, Botta, Bruno
Published in Current pharmaceutical design (01.04.2016)
Published in Current pharmaceutical design (01.04.2016)
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Journal Article
Brain-wide mapping of c-fos expression in the single prolonged stress model and the effects of pretreatment with ACH-000029 or prazosin
Azevedo, Hatylas, Ferreira, Marcos, Mascarello, Alessandra, Osten, Pavel, Guimarães, Cristiano Ruch Werneck
Published in Neurobiology of stress (01.11.2020)
Published in Neurobiology of stress (01.11.2020)
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Journal Article
Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations
Couñago, Rafael M., Allerston, Charles K., Savitsky, Pavel, Azevedo, Hatylas, Godoi, Paulo H., Wells, Carrow I., Mascarello, Alessandra, de Souza Gama, Fernando H., Massirer, Katlin B., Zuercher, William J., Guimarães, Cristiano R. W., Gileadi, Opher
Published in Scientific reports (08.08.2017)
Published in Scientific reports (08.08.2017)
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Journal Article
Anti-prion activity of a panel of aromatic chemical compounds: in vitro and in silico approaches
Ferreira, Natalia C, Marques, Icaro A, Conceição, Wesley A, Macedo, Bruno, Machado, Clarice S, Mascarello, Alessandra, Chiaradia-Delatorre, Louise Domeneghini, Yunes, Rosendo Augusto, Nunes, Ricardo José, Hughson, Andrew G, Raymond, Lynne D, Pascutti, Pedro G, Caughey, Byron, Cordeiro, Yraima
Published in PloS one (06.01.2014)
Published in PloS one (06.01.2014)
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Journal Article
Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: Kinetics, molecular modeling, toxicity and effect on growth
Mascarello, Alessandra, Chiaradia, Louise Domeneghini, Vernal, Javier, Villarino, Andrea, Guido, Rafael V.C., Perizzolo, Paulo, Poirier, Valerie, Wong, Dennis, Martins, Priscila Graziela Alves, Nunes, Ricardo José, Yunes, Rosendo Augusto, Andricopulo, Adriano Defini, Av-Gay, Yossef, Terenzi, Hernán
Published in Bioorganic & medicinal chemistry (01.06.2010)
Published in Bioorganic & medicinal chemistry (01.06.2010)
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Journal Article
Antiherpetic activity of a sulfated polysaccharide from Agaricus brasiliensis mycelia
de Sousa Cardozo, Francielle Tramontini Gomes, Camelini, Carla Maísa, Mascarello, Alessandra, José Rossi, Márcio, José Nunes, Ricardo, Monte Barardi, Célia Regina, de Mendonça, Margarida Matos, Simões, Cláudia Maria Oliveira
Published in Antiviral research (01.10.2011)
Published in Antiviral research (01.10.2011)
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Journal Article
A novel sulfonamide derivative as a strong and selective apototic agent against hematological malignancies
Bigolin, Álisson, Maioral, Mariana F., Stefanes, Natália M., Mascarello, Alessandra, Chiaradia-Delatorre, Louise D., Nunes, Ricardo J., Yunes, Rosendo A., Santos-Silva, Maria Cláudia
Published in Chemical papers (01.09.2020)
Published in Chemical papers (01.09.2020)
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Journal Article
Mechanism of Action of Novel Glibenclamide Derivatives on Potassium and Calcium Channels for Insulin Secretion
Frederico, Marisa Jadna Silva, Castro, Allisson Jhonatan Gomes, Menegaz, Danusa, Murat, Cahue De Bernardis, Mendes, Camila Pires, Mascarello, Alessandra, Nunes, Ricardo Jose, Silva, Fatima Regina Mena Barreto
Published in Current drug targets (01.01.2017)
Published in Current drug targets (01.01.2017)
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Journal Article
Antibacterial activity of chalcones, hydrazones and oxadiazoles against methicillin-resistant Staphylococcus aureus
Moreira Osório, Thaís, Delle Monache, Franco, Domeneghini Chiaradia, Louise, Mascarello, Alessandra, Regina Stumpf, Taisa, Roberto Zanetti, Carlos, Bardini Silveira, Douglas, Regina Monte Barardi, Célia, de Fatima Albino Smânia, Elza, Viancelli, Aline, Ariel Totaro Garcia, Lucas, Augusto Yunes, Rosendo, José Nunes, Ricardo, Smânia, Artur
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
Published in Bioorganic & medicinal chemistry letters (01.01.2012)
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Journal Article
Acylhydrazones contribute to serum glucose homeostasis through dual physiological targets
Frederico, Marisa Jádna Silva, Castro, Allisson Jhonatan Gomes, Mascarello, Alessandra, Mendes, Camila Pires, Kappel, Virgínia Dermachi, Stumpf, Taisa Regina, Leal, Paulo Cesar, Nunes, Ricardo José, Yunes, Rosendo Augusto, Silva, Fátima Regina Mena Barreto
Published in Current topics in medicinal chemistry (01.10.2012)
Published in Current topics in medicinal chemistry (01.10.2012)
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Journal Article
Antimetastatic activity and low systemic toxicity of tetradecyl gallate in a preclinical melanoma mouse model
Locatelli, Claudriana, Carvalho, Deborah Regina, Mascarello, Alessandra, de Cordova, Clarissa Amorin Silva, Yunes, Rosendo Augusto, Nunes, Ricardo Jose, Pilati, Celso, Creczynski-Pasa, Tânia Beatriz
Published in Investigational new drugs (01.06.2012)
Published in Investigational new drugs (01.06.2012)
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Journal Article
Chalcones to control Alternaria alternata in murcott tangor fruits
Camargos, Renato Barbosa, Perina, Fabiano José, Carvalho, Daniel Diego Costa, Alves, Eduardo, Mascarello, Alessandra, Chiaradia-Delatorre, Louise Domeneghini, Yunes, Rosendo Augusto, Nunes, Ricardo José, Oliveira, Denilson Ferreira
Published in Bioscience journal (01.11.2016)
Published in Bioscience journal (01.11.2016)
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Journal Article
Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles
Figueiredo, Claudia P, Ferreira, Natalia C, Passos, Giselle F, Costa, Robson da, Neves, Fernanda S, Machado, Clarice S C, Mascarello, Alessandra, Chiaradia-Delatorre, Louise D, Neuenfeldt, Patrícia D, Nunes, Ricardo J, Cordeiro, Yraima
Published in Anais da Academia Brasileira de Ciências (01.08.2015)
Published in Anais da Academia Brasileira de Ciências (01.08.2015)
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Journal Article
The serotonergic and alpha-1 adrenergic receptor modulator ACH-000029 ameliorates anxiety-like behavior in a post-traumatic stress disorder model
Azevedo, Hatylas, Ferreira, Marcos, Mascarello, Alessandra, Osten, Pavel, Werneck Guimarães, Cristiano Ruch
Published in Neuropharmacology (01.03.2020)
Published in Neuropharmacology (01.03.2020)
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Journal Article
Discovery of ACH-000143: A Novel Potent and Peripherally Preferred Melatonin Receptor Agonist that Reduces Liver Triglycerides and Steatosis in Diet-Induced Obese Rats
Ferreira, Marcos Antonio, Azevedo, Hatylas, Mascarello, Alessandra, Segretti, Natanael Dante, Russo, Elisa, Russo, Valter, Guimarães, Cristiano Ruch Werneck
Published in Journal of medicinal chemistry (25.02.2021)
Published in Journal of medicinal chemistry (25.02.2021)
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Journal Article
Design, synthesis and antihypertensive evaluation of novel codrugs with combined angiotensin type 1 receptor antagonism and neprilysin inhibition
Mascarello, Alessandra, Azevedo, Hatylas, Ferreira Junior, Marcos Antonio, Ishikawa, Eloisa Eriko, Guimarães, Cristiano Ruch Werneck
Published in European journal of pharmaceutical sciences (01.04.2021)
Published in European journal of pharmaceutical sciences (01.04.2021)
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Journal Article
Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
Mascarello, Alessandra, Orbem Menegatti, Angela Camila, Calcaterra, Andrea, Martins, Priscila Graziela Alves, Chiaradia-Delatorre, Louise Domeneghini, D'Acquarica, Ilaria, Ferrari, Franco, Pau, Valentina, Sanna, Adriana, De Logu, Alessandro, Botta, Maurizio, Botta, Bruno, Terenzi, Hernán, Mori, Mattia
Published in European journal of medicinal chemistry (20.01.2018)
Published in European journal of medicinal chemistry (20.01.2018)
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Journal Article
Preclinical characterization of ACH-000029, a novel anxiolytic compound acting on serotonergic and alpha-adrenergic receptors
Azevedo, Hatylas, Ferreira, Marcos, Costa, Renata Watanabe, Russo, Valter, Russo, Elisa, Mascarello, Alessandra, Guimarães, Cristiano Ruch Werneck
Published in Progress in neuro-psychopharmacology & biological psychiatry (20.12.2019)
Published in Progress in neuro-psychopharmacology & biological psychiatry (20.12.2019)
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Journal Article