Therapeutic high affinity T cell receptor targeting a KRASG12D cancer neoantigen
Poole, Andrew, Karuppiah, Vijaykumar, Hartt, Annabelle, Haidar, Jaafar N., Moureau, Sylvie, Dobrzycki, Tomasz, Hayes, Conor, Rowley, Christopher, Dias, Jorge, Harper, Stephen, Barnbrook, Keir, Hock, Miriam, Coles, Charlotte, Yang, Wei, Aleksic, Milos, Lin, Aimee Bence, Robinson, Ross, Dukes, Joe D., Liddy, Nathaniel, Van der Kamp, Marc, Plowman, Gregory D., Vuidepot, Annelise, Cole, David K., Whale, Andrew D., Chillakuri, Chandramouli
Published in Nature communications (10.09.2022)
Published in Nature communications (10.09.2022)
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Journal Article
Different affinity windows for virus and cancer‐specific T‐cell receptors: Implications for therapeutic strategies
Aleksic, Milos, Liddy, Nathaniel, Molloy, Peter E., Pumphrey, Nick, Vuidepot, Annelise, Chang, Kyong‐Mi, Jakobsen, Bent K.
Published in European journal of immunology (01.12.2012)
Published in European journal of immunology (01.12.2012)
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C-Peptide Induces Chemotaxis of Human CD4-Positive Cells
Walcher, Daniel, Aleksic, Milos, Jerg, Verena, Hombach, Vinzenz, Zieske, Arthur, Homma, Satoki, Strong, Jack, Marx, Nikolaus
Published in Diabetes (New York, N.Y.) (01.07.2004)
Published in Diabetes (New York, N.Y.) (01.07.2004)
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Specificity of bispecific T cell receptors and antibodies targeting peptide-HLA
Holland, Christopher J, Crean, Rory M, Pentier, Johanne M, de Wet, Ben, Lloyd, Angharad, Srikannathasan, Velupillai, Lissin, Nikolai, Lloyd, Katy A, Blicher, Thomas H, Conroy, Paul J, Hock, Miriam, Pengelly, Robert J, Spinner, Thomas E, Cameron, Brian, Potter, Elizabeth A, Jeyanthan, Anitha, Molloy, Peter E, Sami, Malkit, Aleksic, Milos, Liddy, Nathaniel, Robinson, Ross A, Harper, Stephen, Lepore, Marco, Pudney, Chris R, van der Kamp, Marc W, Rizkallah, Pierre J, Jakobsen, Bent K, Vuidepot, Annelise, Cole, David K
Published in The Journal of clinical investigation (01.05.2020)
Published in The Journal of clinical investigation (01.05.2020)
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Dependence of T Cell Antigen Recognition on T Cell Receptor-Peptide MHC Confinement Time
Aleksic, Milos, Dushek, Omer, Zhang, Hao, Shenderov, Eugene, Chen, Ji-Li, Cerundolo, Vincenzo, Coombs, Daniel, van der Merwe, P. Anton
Published in Immunity (Cambridge, Mass.) (26.02.2010)
Published in Immunity (Cambridge, Mass.) (26.02.2010)
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TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex
Coles, Charlotte H, Mulvaney, Rachel M, Malla, Sunir, Walker, Andrew, Smith, Kathrine J, Lloyd, Angharad, Lowe, Kate L, McCully, Michelle L, Martinez Hague, Ruth, Aleksic, Milos, Harper, Jane, Paston, Samantha J, Donnellan, Zoe, Chester, Fiona, Wiederhold, Katrin, Robinson, Ross A, Knox, Andrew, Stacey, Andrea R, Dukes, Joseph, Baston, Emma, Griffin, Sue, Jakobsen, Bent K, Vuidepot, Annelise, Harper, Stephen
Published in The Journal of immunology (1950) (01.04.2020)
Published in The Journal of immunology (1950) (01.04.2020)
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Elimination of Latently HIV-infected Cells from Antiretroviral Therapy-suppressed Subjects by Engineered Immune-mobilizing T-cell Receptors
Yang, Hongbing, Buisson, Sandrine, Bossi, Giovanna, Wallace, Zoë, Hancock, Gemma, So, Chun, Ashfield, Rebecca, Vuidepot, Annelise, Mahon, Tara, Molloy, Peter, Oates, Joanne, Paston, Samantha J, Aleksic, Milos, Hassan, Namir J, Jakobsen, Bent K, Dorrell, Lucy
Published in Molecular therapy (01.11.2016)
Published in Molecular therapy (01.11.2016)
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Bi-specific TCR-anti CD3 redirected T-cell targeting of NY-ESO-1- and LAGE-1-positive tumors
McCormack, Emmet, Adams, Katherine J., Hassan, Namir J., Kotian, Akhil, Lissin, Nikolai M., Sami, Malkit, Mujić, Maja, Osdal, Tereza, Gjertsen, Bjørn Tore, Baker, Deborah, Powlesland, Alex S., Aleksic, Milos, Vuidepot, Annelise, Morteau, Olivier, Sutton, Deborah H., June, Carl H., Kalos, Michael, Ashfield, Rebecca, Jakobsen, Bent K.
Published in Cancer Immunology, Immunotherapy (01.04.2013)
Published in Cancer Immunology, Immunotherapy (01.04.2013)
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The contribution of major histocompatibility complex contacts to the affinity and kinetics of T cell receptor binding
Zhang, Hao, Lim, Hong-Sheng, Knapp, Berhard, Deane, Charlotte M., Aleksic, Milos, Dushek, Omer, van der Merwe, P. Anton
Published in Scientific reports (13.10.2016)
Published in Scientific reports (13.10.2016)
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Abstract 3467: GRWD5769: A first-in-class inhibitor of ERAP1, generating novel cancer antigens to drive de novo anti-tumor T cell responses
Leishman, Andrew, Paes, Wayne, Sparrow, Emma, Ribeiro, Ana, Cundell, Michael, Aleksic, Milos, Pinggera, Michael P., Sette, Jessica, Anderton, Kate, Ternette, Nicola, Morgan, Juliet, Shiers, Jason J., Quibell, Martin, Joyce, Peter I.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Antigen potency and maximal efficacy reveal a mechanism of efficient T cell activation
Dushek, Omer, Aleksic, Milos, Wheeler, Richard J, Zhang, Hao, Cordoba, Shaun-Paul, Peng, Yan-Chun, Chen, Ji-Li, Cerundolo, Vincenzo, Dong, Tao, Coombs, Daniel, van der Merwe, P Anton
Published in Science signaling (07.06.2011)
Published in Science signaling (07.06.2011)
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Journal Article
Therapeutic high affinity T cell receptor targeting a KRAS G12D cancer neoantigen
Poole, Andrew, Karuppiah, Vijaykumar, Hartt, Annabelle, Haidar, Jaafar N, Moureau, Sylvie, Dobrzycki, Tomasz, Hayes, Conor, Rowley, Christopher, Dias, Jorge, Harper, Stephen, Barnbrook, Keir, Hock, Miriam, Coles, Charlotte, Yang, Wei, Aleksic, Milos, Lin, Aimee Bence, Robinson, Ross, Dukes, Joe D, Liddy, Nathaniel, Van der Kamp, Marc, Plowman, Gregory D, Vuidepot, Annelise, Cole, David K, Whale, Andrew D, Chillakuri, Chandramouli
Published in Nature communications (10.09.2022)
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Published in Nature communications (10.09.2022)
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