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Roberts, Ryan D., Lizardo, Michael M., Reed, Damon R., Hingorani, Pooja, Glover, Jason, Allen‐Rhoades, Wendy, Fan, Timothy, Khanna, Chand, Sweet‐Cordero, E. Alejandro, Cash, Thomas, Bishop, Michael W., Hegde, Meenakshi, Sertil, Aparna R., Koelsche, Christian, Mirabello, Lisa, Malkin, David, Sorensen, Poul H., Meltzer, Paul S., Janeway, Katherine A., Gorlick, Richard, Crompton, Brian D.
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UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma
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Loss of p130 Accelerates Tumor Development in a Mouse Model for Human Small-Cell Lung Carcinoma
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Cross-Species Functional Analysis of Cancer-Associated Fibroblasts Identifies a Critical Role for CLCF1 and IL-6 in Non-Small Cell Lung Cancer In Vivo
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Published in Cancer research (Chicago, Ill.) (15.11.2012)
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A 3D Osteosarcoma Model with Bone-Mimicking Cues Reveals a Critical Role of Bone Mineral and Informs Drug Discovery
González Díaz, Eva C, Lee, Alex G, Sayles, Leanne C, Feria, Criselle, Sweet-Cordero, E Alejandro, Yang, Fan
Published in Advanced healthcare materials (01.09.2022)
Published in Advanced healthcare materials (01.09.2022)
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Charting a path for prioritization of novel agents for clinical trials in osteosarcoma: A report from the Children's Oncology Group New Agents for Osteosarcoma Task Force
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Published in Pediatric blood & cancer (01.09.2021)
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Hydra: A mixture modeling framework for subtyping pediatric cancer cohorts using multimodal gene expression signatures
Pfeil, Jacob, Sanders, Lauren M, Anastopoulos, Ioannis, Lyle, A Geoffrey, Weinstein, Alana S, Xue, Yuanqing, Blair, Andrew, Beale, Holly C, Lee, Alex, Leung, Stanley G, Dinh, Phuong T, Shah, Avanthi Tayi, Breese, Marcus R, Devine, W Patrick, Bjork, Isabel, Salama, Sofie R, Sweet-Cordero, E Alejandro, Haussler, David, Vaske, Olena Morozova
Published in PLoS computational biology (10.04.2020)
Published in PLoS computational biology (10.04.2020)
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Pre‐and post‐HSCT use of TKI therapy for fusion‐driven B‐ALL: A case series of five pediatric, adolescent and young adult patients
Shumock, Savannah S., Temple, William C., Marinoff, Amanda, Aaronson, Kathryn, Southworth, Erica, Xirenayi, Simayijiang, Lee, Alex G., Leung, Stanley G., Sweet‐Cordero, E. Alejandro, Hermiston, Michelle, Higham, Christine, Stieglitz, Elliot
Published in Cancer reports (01.12.2023)
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Germline Predisposition and Copy Number Alteration in Pre-stage Lung Adenocarcinomas Presenting as Ground-Glass Nodules
Ren, Yijiu, Huang, Shujun, Dai, Chenyang, Xie, Dong, Zheng, Larry, Xie, Huikang, Zheng, Hui, She, Yunlang, Zhou, Fangyu, Wang, Yue, Li, Pengpeng, Fei, Ke, Jiang, Gening, Zhang, Yang, Su, Bo, Sweet-Cordero, E Alejandro, Tran, Nhan Le, Yang, Yanan, Patel, Jai N, Rolfo, Christian, Rocco, Gaetano, Cardona, Andrés Felipe, Tuzi, Alessandro, Suter, Matteo B, Yang, Ping, Xu, Wayne, Chen, Chang
Published in Frontiers in oncology (18.04.2019)
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Sayles, Leanne C, Breese, Marcus R, Koehne, Amanda L, Leung, Stanley G, Lee, Alex G, Liu, Heng-Yi, Spillinger, Aviv, Shah, Avanthi T, Tanasa, Bogdan, Straessler, Krystal, Hazard, Florette K, Spunt, Sheri L, Marina, Neyssa, Kim, Grace E, Cho, Soo-Jin, Avedian, Raffi S, Mohler, David G, Kim, Mi-Ok, DuBois, Steven G, Hawkins, Douglas S, Sweet-Cordero, E Alejandro
Published in Cancer discovery (01.01.2019)
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Molecular definition of a metastatic lung cancer state reveals a targetable CD109–Janus kinase–Stat axis
Chuang, Chen-Hua, Greenside, Peyton G, Rogers, Zoë N, Brady, Jennifer J, Yang, Dian, Ma, Rosanna K, Caswell, Deborah R, Chiou, Shin-Heng, Winters, Aidan F, Grüner, Barbara M, Ramaswami, Gokul, Spencley, Andrew L, Kopecky, Kimberly E, Sayles, Leanne C, Sweet-Cordero, E Alejandro, Li, Jin Billy, Kundaje, Anshul, Winslow, Monte M
Published in Nature medicine (01.03.2017)
Published in Nature medicine (01.03.2017)
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An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer
Vallejo, Adrian, Perurena, Naiara, Guruceaga, Elisabet, Mazur, Pawel K., Martinez-Canarias, Susana, Zandueta, Carolina, Valencia, Karmele, Arricibita, Andrea, Gwinn, Dana, Sayles, Leanne C., Chuang, Chen-Hua, Guembe, Laura, Bailey, Peter, Chang, David K., Biankin, Andrew, Ponz-Sarvise, Mariano, Andersen, Jesper B., Khatri, Purvesh, Bozec, Aline, Sweet-Cordero, E. Alejandro, Sage, Julien, Lecanda, Fernando, Vicent, Silve
Published in Nature communications (21.02.2017)
Published in Nature communications (21.02.2017)
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Direct transposition of native DNA for sensitive multimodal single-molecule sequencing
Nanda, Arjun S., Wu, Ke, Irkliyenko, Iryna, Woo, Brian, Ostrowski, Megan S., Clugston, Andrew S., Sayles, Leanne C., Xu, Lingru, Satpathy, Ansuman T., Nguyen, Hao G., Alejandro Sweet-Cordero, E., Goodarzi, Hani, Kasinathan, Sivakanthan, Ramani, Vijay
Published in Nature genetics (01.06.2024)
Published in Nature genetics (01.06.2024)
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Antitumor activity of an engineered decoy receptor targeting CLCF1–CNTFR signaling in lung adenocarcinoma
Kim, Jun W., Marquez, Cesar P., Kostyrko, Kaja, Koehne, Amanda L., Marini, Kieren, Simpson, David R., Lee, Alex G., Leung, Stanley G., Sayles, Leanne C., Shrager, Joseph, Ferrer, Irene, Paz-Ares, Luis, Gephart, Melanie Hayden, Vicent, Silvestre, Cochran, Jennifer R., Sweet-Cordero, E. Alejandro
Published in Nature medicine (01.11.2019)
Published in Nature medicine (01.11.2019)
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An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency
Brady, Jennifer J., Chuang, Chen-Hua, Greenside, Peyton G., Rogers, Zoë N., Murray, Christopher W., Caswell, Deborah R., Hartmann, Ursula, Connolly, Andrew J., Sweet-Cordero, E. Alejandro, Kundaje, Anshul, Winslow, Monte M.
Published in Cancer cell (09.05.2016)
Published in Cancer cell (09.05.2016)
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Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses
Broyde, Joshua, Simpson, David R., Murray, Diana, Paull, Evan O., Chu, Brennan W., Tagore, Somnath, Jones, Sunny J., Griffin, Aaron T., Giorgi, Federico M., Lachmann, Alexander, Jackson, Peter, Sweet-Cordero, E. Alejandro, Honig, Barry, Califano, Andrea
Published in Nature biotechnology (01.02.2021)
Published in Nature biotechnology (01.02.2021)
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Single-cell analysis of hepatoblastoma identifies tumor signatures that predict chemotherapy susceptibility using patient-specific tumor spheroids
Song, Hanbing, Bucher, Simon, Rosenberg, Katherine, Tsui, Margaret, Burhan, Deviana, Hoffman, Daniel, Cho, Soo-Jin, Rangaswami, Arun, Breese, Marcus, Leung, Stanley, Ventura, María V. Pons, Sweet-Cordero, E. Alejandro, Huang, Franklin W., Nijagal, Amar, Wang, Bruce
Published in Nature communications (25.08.2022)
Published in Nature communications (25.08.2022)
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The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
Valencia, Karmele, Erice, Oihane, Kostyrko, Kaja, Hausmann, Simone, Guruceaga, Elizabeth, Tathireddy, Anuradha, Flores, Natasha M, Sayles, Leanne C, Lee, Alex G, Fragoso, Rita, Sun, Tian-Qiang, Vallejo, Adrian, Roman, Marta, Entrialgo-Cadierno, Rodrigo, Migueliz, Itziar, Razquin, Nerea, Fortes, Puri, Lecanda, Fernando, Lu, Jun, Ponz-Sarvise, Mariano, Chen, Chang-Zheng, Mazur, Pawel K, Sweet-Cordero, E Alejandro, Vicent, Silvestre
Published in The Journal of clinical investigation (01.04.2020)
Published in The Journal of clinical investigation (01.04.2020)
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