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Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
Blanco-Melo, Daniel, Nilsson-Payant, Benjamin E., Liu, Wen-Chun, Uhl, Skyler, Hoagland, Daisy, Møller, Rasmus, Jordan, Tristan X., Oishi, Kohei, Panis, Maryline, Sachs, David, Wang, Taia T., Schwartz, Robert E., Lim, Jean K., Albrecht, Randy A., tenOever, Benjamin R.
Published in Cell (28.05.2020)
Published in Cell (28.05.2020)
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Broadly-Reactive Neutralizing and Non-neutralizing Antibodies Directed against the H7 Influenza Virus Hemagglutinin Reveal Divergent Mechanisms of Protection
Tan, Gene S., Leon, Paul E., Albrecht, Randy A., Margine, Irina, Hirsh, Ariana, Bahl, Justin, Krammer, Florian
Published in PLoS pathogens (01.04.2016)
Published in PLoS pathogens (01.04.2016)
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Mutations in SARS-CoV-2 variants of concern link to increased spike cleavage and virus transmission
Escalera, Alba, Gonzalez-Reiche, Ana S., Aslam, Sadaf, Mena, Ignacio, Laporte, Manon, Pearl, Rebecca L., Fossati, Andrea, Rathnasinghe, Raveen, Alshammary, Hala, van de Guchte, Adriana, Farrugia, Keith, Qin, Yiren, Bouhaddou, Mehdi, Kehrer, Thomas, Zuliani-Alvarez, Lorena, Meekins, David A., Balaraman, Velmurugan, McDowell, Chester, Richt, Jürgen A., Bajic, Goran, Sordillo, Emilia Mia, Dejosez, Marion, Zwaka, Thomas P., Krogan, Nevan J., Simon, Viviana, Albrecht, Randy A., van Bakel, Harm, García-Sastre, Adolfo, Aydillo, Teresa
Published in Cell host & microbe (09.03.2022)
Published in Cell host & microbe (09.03.2022)
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Advances and gaps in SARS-CoV-2 infection models
Muñoz-Fontela, César, Widerspick, Lina, Albrecht, Randy A., Beer, Martin, Carroll, Miles W., de Wit, Emmie, Diamond, Michael S., Dowling, William E., Funnell, Simon G. P., García-Sastre, Adolfo, Gerhards, Nora M., de Jong, Rineke, Munster, Vincent J., Neyts, Johan, Perlman, Stanley, Reed, Douglas S., Richt, Juergen A., Riveros-Balta, Ximena, Roy, Chad J., Salguero, Francisco J., Schotsaert, Michael, Schwartz, Lauren M., Seder, Robert A., Segalés, Joaquim, Vasan, Seshadri S., Henao-Restrepo, Ana María, Barouch, Dan H.
Published in PLoS pathogens (01.01.2022)
Published in PLoS pathogens (01.01.2022)
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Influenza A Virus Transmission Bottlenecks Are Defined by Infection Route and Recipient Host
Varble, Andrew, Albrecht, Randy A., Backes, Simone, Crumiller, Marshall, Bouvier, Nicole M., Sachs, David, García-Sastre, Adolfo, tenOever, Benjamin R.
Published in Cell host & microbe (12.11.2014)
Published in Cell host & microbe (12.11.2014)
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Meta- and Orthogonal Integration of Influenza “OMICs” Data Defines a Role for UBR4 in Virus Budding
Tripathi, Shashank, Pohl, Marie O., Zhou, Yingyao, Rodriguez-Frandsen, Ariel, Wang, Guojun, Stein, David A., Moulton, Hong M., DeJesus, Paul, Che, Jianwei, Mulder, Lubbertus C.F., Yángüez, Emilio, Andenmatten, Dario, Pache, Lars, Manicassamy, Balaji, Albrecht, Randy A., Gonzalez, Maria G., Nguyen, Quy, Brass, Abraham, Elledge, Stephen, White, Michael, Shapira, Sagi, Hacohen, Nir, Karlas, Alexander, Meyer, Thomas F., Shales, Michael, Gatorano, Andre, Johnson, Jeffrey R., Jang, Gwen, Johnson, Tasha, Verschueren, Erik, Sanders, Doug, Krogan, Nevan, Shaw, Megan, König, Renate, Stertz, Silke, García-Sastre, Adolfo, Chanda, Sumit K.
Published in Cell host & microbe (09.12.2015)
Published in Cell host & microbe (09.12.2015)
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Species-Specific Inhibition of RIG-I Ubiquitination and IFN Induction by the Influenza A Virus NS1 Protein
Rajsbaum, Ricardo, Albrecht, Randy A., Wang, May K., Maharaj, Natalya P., Versteeg, Gijs A., Nistal-Villán, Estanislao, García-Sastre, Adolfo, Gack, Michaela U.
Published in PLoS pathogens (01.11.2012)
Published in PLoS pathogens (01.11.2012)
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Defining the antibody cross-reactome directed against the influenza virus surface glycoproteins
Nachbagauer, Raffael, Choi, Angela, Hirsh, Ariana, Margine, Irina, Iida, Sayaka, Barrera, Aldo, Ferres, Marcela, Albrecht, Randy A, García-Sastre, Adolfo, Bouvier, Nicole M, Ito, Kimihito, Medina, Rafael A, Palese, Peter, Krammer, Florian
Published in Nature immunology (01.04.2017)
Published in Nature immunology (01.04.2017)
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A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses
Tripathi, Shashank, Balasubramaniam, Vinod R. M. T., Brown, Julia A., Mena, Ignacio, Grant, Alesha, Bardina, Susana V., Maringer, Kevin, Schwarz, Megan C., Maestre, Ana M., Sourisseau, Marion, Albrecht, Randy A., Krammer, Florian, Evans, Matthew J., Fernandez-Sesma, Ana, Lim, Jean K., García-Sastre, Adolfo
Published in PLoS pathogens (09.03.2017)
Published in PLoS pathogens (09.03.2017)
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An In Vitro Microneutralization Assay for SARS-CoV-2 Serology and Drug Screening
Amanat, Fatima, White, Kris M, Miorin, Lisa, Strohmeier, Shirin, McMahon, Meagan, Meade, Philip, Liu, Wen-Chun, Albrecht, Randy A, Simon, Viviana, Martinez-Sobrido, Luis, Moran, Thomas, García-Sastre, Adolfo, Krammer, Florian
Published in Current protocols in microbiology (Online) (01.09.2020)
Published in Current protocols in microbiology (Online) (01.09.2020)
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Influenza Viruses Expressing Chimeric Hemagglutinins: Globular Head and Stalk Domains Derived from Different Subtypes
Hai, Rong, Krammer, Florian, Tan, Gene S, Pica, Natalie, Eggink, Dirk, Maamary, Jad, Margine, Irina, Albrecht, Randy A, Palese, Peter
Published in Journal of Virology (01.05.2012)
Published in Journal of Virology (01.05.2012)
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A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics
Si, Longlong, Bai, Haiqing, Rodas, Melissa, Cao, Wuji, Oh, Crystal Yuri, Jiang, Amanda, Moller, Rasmus, Hoagland, Daisy, Oishi, Kohei, Horiuchi, Shu, Uhl, Skyler, Blanco-Melo, Daniel, Albrecht, Randy A., Liu, Wen-Chun, Jordan, Tristan, Nilsson-Payant, Benjamin E., Golynker, Ilona, Frere, Justin, Logue, James, Haupt, Robert, McGrath, Marisa, Weston, Stuart, Zhang, Tian, Plebani, Roberto, Soong, Mercy, Nurani, Atiq, Kim, Seong Min, Zhu, Danni Y., Benam, Kambez H., Goyal, Girija, Gilpin, Sarah E., Prantil-Baun, Rachelle, Gygi, Steven P., Powers, Rani K., Carlson, Kenneth E., Frieman, Matthew, tenOever, Benjamin R., Ingber, Donald E.
Published in Nature biomedical engineering (01.08.2021)
Published in Nature biomedical engineering (01.08.2021)
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Microbiome disturbance and resilience dynamics of the upper respiratory tract during influenza A virus infection
Kaul, Drishti, Rathnasinghe, Raveen, Ferres, Marcela, Tan, Gene S., Barrera, Aldo, Pickett, Brett E., Methe, Barbara A., Das, Suman R., Budnik, Isolda, Halpin, Rebecca A., Wentworth, David, Schmolke, Mirco, Mena, Ignacio, Albrecht, Randy A., Singh, Indresh, Nelson, Karen E., García-Sastre, Adolfo, Dupont, Chris L., Medina, Rafael A.
Published in Nature communications (21.05.2020)
Published in Nature communications (21.05.2020)
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Suppression of the antiviral response by an influenza histone mimic
Marazzi, Ivan, Ho, Jessica S. Y., Kim, Jaehoon, Manicassamy, Balaji, Dewell, Scott, Albrecht, Randy A., Seibert, Chris W., Schaefer, Uwe, Jeffrey, Kate L., Prinjha, Rab K., Lee, Kevin, García-Sastre, Adolfo, Roeder, Robert G., Tarakhovsky, Alexander
Published in Nature (London) (22.03.2012)
Published in Nature (London) (22.03.2012)
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H3N2 Influenza Virus Infection Induces Broadly Reactive Hemagglutinin Stalk Antibodies in Humans and Mice
Margine, Irina, Hai, Rong, Albrecht, Randy A., Obermoser, Gerlinde, Harrod, A. Carson, Banchereau, Jacques, Palucka, Karolina, García-Sastre, Adolfo, Palese, Peter, Treanor, John J., Krammer, Florian
Published in Journal of Virology (01.04.2013)
Published in Journal of Virology (01.04.2013)
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Macroautophagy Proteins Control MHC Class I Levels on Dendritic Cells and Shape Anti-viral CD8+ T Cell Responses
Loi, Monica, Müller, Anne, Steinbach, Karin, Niven, Jennifer, Barreira da Silva, Rosa, Paul, Petra, Ligeon, Laure-Anne, Caruso, Assunta, Albrecht, Randy A., Becker, Andrea C., Annaheim, Nicolas, Nowag, Heike, Dengjel, Jörn, García-Sastre, Adolfo, Merkler, Doron, Münz, Christian, Gannagé, Monique
Published in Cell reports (Cambridge) (03.05.2016)
Published in Cell reports (Cambridge) (03.05.2016)
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Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets
Krammer, Florian, Hai, Rong, Yondola, Mark, Tan, Gene S, Leyva-Grado, Victor H, Ryder, Alex B, Miller, Matthew S, Rose, John K, Palese, Peter, García-Sastre, Adolfo, Albrecht, Randy A
Published in Journal of Virology (01.03.2014)
Published in Journal of Virology (01.03.2014)
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A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA
Bangaru, Sandhya, Zhang, Heng, Gilchuk, Iuliia M., Voss, Thomas G., Irving, Ryan P., Gilchuk, Pavlo, Matta, Pranathi, Zhu, Xueyong, Lang, Shanshan, Nieusma, Travis, Richt, Juergen A., Albrecht, Randy A., Vanderven, Hillary A., Bombardi, Robin, Kent, Stephen J., Ward, Andrew B., Wilson, Ian A., Crowe, James E.
Published in Nature communications (10.07.2018)
Published in Nature communications (10.07.2018)
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Vaccination With Viral Vectors Expressing Chimeric Hemagglutinin, NP and M1 Antigens Protects Ferrets Against Influenza Virus Challenge
McMahon, Meagan, Asthagiri Arunkumar, Guha, Liu, Wen-Chun, Stadlbauer, Daniel, Albrecht, Randy A., Pavot, Vincent, Aramouni, Mario, Lambe, Teresa, Gilbert, Sarah C., Krammer, Florian
Published in Frontiers in immunology (21.08.2019)
Published in Frontiers in immunology (21.08.2019)
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Moving Forward: Recent Developments for the Ferret Biomedical Research Model
Albrecht, Randy A., Liu, Wen-Chun, Sant, Andrea J., Tompkins, S. Mark, Pekosz, Andrew, Meliopoulos, Victoria, Cherry, Sean, Thomas, Paul G., Schultz-Cherry, Stacey
Published in mBio (17.07.2018)
Published in mBio (17.07.2018)
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