MORAb-202, an Antibody-Drug Conjugate Utilizing Humanized Anti-human FRα Farletuzumab and the Microtubule-targeting Agent Eribulin, has Potent Antitumor Activity
Cheng, Xin, Li, Jing, Tanaka, Keigo, Majumder, Utpal, Milinichik, Andrew Z, Verdi, Arielle C, Maddage, Christopher J, Rybinski, Katherine A, Fernando, Shawn, Fernando, Danielle, Kuc, Megan, Furuuchi, Keiji, Fang, Frank, Uenaka, Toshimitsu, Grasso, Luigi, Albone, Earl F
Published in Molecular cancer therapeutics (01.12.2018)
Published in Molecular cancer therapeutics (01.12.2018)
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Antibody‐drug conjugate MORAb‐202 exhibits long‐lasting antitumor efficacy in TNBC PDx models
Furuuchi, Keiji, Rybinski, Katherine, Fulmer, James, Moriyama, Tomoyuki, Drozdowski, Brian, Soto, Allis, Fernando, Shawn, Wilson, Kerrianne, Milinichik, Andrew, Dula, Mary Lou, Tanaka, Keigo, Cheng, Xin, Albone, Earl, Uenaka, Toshimitsu
Published in Cancer science (01.06.2021)
Published in Cancer science (01.06.2021)
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Bioconjugation by Native Chemical Tagging of C–H Bonds
Zhou, Qianghui, Gui, Jinghan, Pan, Chung-Mao, Albone, Earl, Cheng, Xin, Suh, Edward M, Grasso, Luigi, Ishihara, Yoshihiro, Baran, Phil S
Published in Journal of the American Chemical Society (04.09.2013)
Published in Journal of the American Chemical Society (04.09.2013)
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Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease
Roberts, Malcolm, Sevastou, Ioanna, Imaizumi, Yoichi, Mistry, Kavita, Talma, Sonia, Dey, Madhurima, Gartlon, Jane, Ochiai, Hiroshi, Zhou, Zhi, Akasofu, Shigeru, Tokuhara, Naoki, Ogo, Makoto, Aoyama, Muneo, Aoyagi, Hirofumi, Strand, Kate, Sajedi, Ezat, Agarwala, Kishan Lal, Spidel, Jared, Albone, Earl, Horie, Kanta, Staddon, James M, de Silva, Rohan
Published in Acta neuropathologica communications (04.02.2020)
Published in Acta neuropathologica communications (04.02.2020)
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Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe
Jouanneau, Morgan, McClary, Brandon, Reyes, Jeremy Chris P., Chen, Rong, Chen, Yuling, Plunkett, William, Cheng, Xin, Milinichik, Andrew Z., Albone, Earl F., Liu, Jun O., Romo, Daniel
Published in Bioorganic & medicinal chemistry letters (15.04.2016)
Published in Bioorganic & medicinal chemistry letters (15.04.2016)
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Single Dose GLP-1-Tf Ameliorates Myocardial Ischemia/Reperfusion Injury
Matsubara, Muneaki, M.D, Kanemoto, Shinya, M.D, Leshnower, Bradley G., M.D, Albone, Earl F., Ph.D, Hinmon, Robin, M.S, Plappert, Theodore, C.V.T, Gorman, Joseph H., M.D, Gorman, Robert C., M.D
Published in The Journal of surgical research (01.01.2011)
Published in The Journal of surgical research (01.01.2011)
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The antitumor activity of the human FOLR1-specific monoclonal antibody, farletuzumab, in an ovarian cancer mouse model is mediated by antibody-dependent cellular cytotoxicity
Lin, JianMin, Spidel, Jared L, Maddage, Christopher J, Rybinski, Katherine A, Kennedy, Rina P, Krauthauser, Candice LM, Park, Young Chul, Albone, Earl F, Jacob, Sara, Goserud, Matthew T, Martinez, Bryon P, Chao, Qimin, Zhou, Yuhong, Nicolaides, Nicholas C, Kline, J Bradford, Grasso, Luigi
Published in Cancer biology & therapy (01.11.2013)
Published in Cancer biology & therapy (01.11.2013)
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Generation of therapeutic immunoconjugates via Residue-Specific Conjugation Technology (RESPECT) utilizing a native cysteine in the light chain framework of Oryctolagus cuniculus
Albone, Earl F., Spidel, Jared L., Cheng, Xin, Park, Young Chul, Jacob, Sara, Milinichik, Andrew Z., Vaessen, Ben, Butler, Janet, Kline, J. Bradford, Grasso, Luigi
Published in Cancer biology & therapy (04.05.2017)
Published in Cancer biology & therapy (04.05.2017)
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Targeting endosialin/CD248 through antibody-mediated internalization results in impaired pericyte maturation and dysfunctional tumor microvasculature
Rybinski, Katherine, Imtiyaz, Hongxia Z, Mittica, Barrie, Drozdowski, Brian, Fulmer, James, Furuuchi, Keiji, Fernando, Shawn, Henry, Marianne, Chao, Qimin, Kline, Brad, Albone, Earl, Wustner, Jason, Lin, JianMin, Nicolaides, Nicholas C, Grasso, Luigi, Zhou, Yuhong
Published in Oncotarget (22.09.2015)
Published in Oncotarget (22.09.2015)
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Engineering humanized antibody framework sequences for optimal site-specific conjugation of cytotoxins
Spidel, Jared L, Albone, Earl F, Cheng, Xin, Vaessen, Benjamin, Jacob, Sara, Milinichik, Andrew Z, Verdi, Arielle, Kline, J Bradford, Grasso, Luigi
Published in mAbs (18.08.2017)
Published in mAbs (18.08.2017)
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Characterization of the human folate receptor alpha via novel antibody-based probes
O'Shannessy, Daniel J, Somers, Elizabeth B, Albone, Earl, Cheng, Xin, Park, Young Chul, Tomkowicz, Brian E, Hamuro, Yoshitomo, Kohl, Thomas O, Forsyth, Tracy M, Smale, Robert, Fu, Yao-Shi, Nicolaides, Nicholas C
Published in Oncotarget (01.12.2011)
Published in Oncotarget (01.12.2011)
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Effect of chelator conjugation level and injection dose on tumor and organ uptake of 111In-labeled MORAb-009, an anti-mesothelin antibody
Shin, In Soo, Lee, Sang-Myung, Kim, Hyung Sub, Yao, Zhengsheng, Regino, Celeste, Sato, Noriko, Cheng, Kenneth T., Hassan, Raffit, Campo, Melissa F., Albone, Earl F., Choyke, Peter L., Pastan, Ira, Paik, Chang H.
Published in Nuclear medicine and biology (01.11.2011)
Published in Nuclear medicine and biology (01.11.2011)
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A novel concept for cleavable linkers applicable to conjugation chemistry - design, synthesis and characterization
Majumder, Utpal, Zhu, Xiaojie, Custar, Daniel, Li, Danyang, Fang, Hui, McGonigle, Sharon, Albone, Earl, Cheng, Xin, Lai, Weidong, Siu, Amy, Bresciano, Karen, Hart, Andrew, Postema, Maarten
Published in Chembiochem : a European journal of chemical biology (18.10.2024)
Published in Chembiochem : a European journal of chemical biology (18.10.2024)
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Characterization of Antibodies to CA 125 that Bind Preferentially to the Cell-Associated Form of the Antigen
Singleton, Judith, Guillen, Darlene E., Scully, Michael S., Xue, Jiyan, Moffet, Jennifer, Chen, Chaoyuan, Patel, Sima R., Schilling, Adriane, Corisdeo, Susanne, Yang, Qifeng, Wang, Baiyang, Soltis, Daniel A., Albone, Earl F.
Published in Tumor biology (01.01.2006)
Published in Tumor biology (01.01.2006)
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Pharmacokinetics, biodistribution, and radioimmunotherapy with monoclonal antibody 776.1 in a murine model of human ovarian cancer
Berger, Marc A, Masters, Gregg R, Singleton, Judith, Scully, Michael S, Grimm, Lisa G, Soltis, Daniel A, Albone, Earl F
Published in Cancer biotherapy & radiopharmaceuticals (01.12.2005)
Published in Cancer biotherapy & radiopharmaceuticals (01.12.2005)
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