Discovery of Mitogen-Activated Protein Kinase-Interacting Kinase 1 Inhibitors by a Comprehensive Fragment-Oriented Virtual Screening Approach
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Published in Journal of medicinal chemistry (23.09.2010)
Published in Journal of medicinal chemistry (23.09.2010)
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Chemical Interrogation of FOXO3a Nuclear Translocation Identifies Potent and Selective Inhibitors of Phosphoinositide 3-Kinases
Link, Wolfgang, Oyarzabal, Julen, Serelde, Beatriz G., Albarran, Maria Isabel, Rabal, Obdulia, Cebriá, Antonio, Alfonso, Patricia, Fominaya, Jesus, Renner, Oliver, Peregrina, Sandra, Soilán, David, Ceballos, Plácido A., Hernández, Ana-Isabel, Lorenzo, Milagros, Pevarello, Paolo, Granda, Teresa G., Kurz, Guido, Carnero, Amancio, Bischoff, James R.
Published in The Journal of biological chemistry (09.10.2009)
Published in The Journal of biological chemistry (09.10.2009)
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Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells
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Published in Cancers (04.07.2020)
Published in Cancers (04.07.2020)
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Martínez-González, Sonia, Rodríguez-Arístegui, Sonsoles, Gómez de la Oliva, Cristina Ana, Hernández, Ana Isabel, González Cantalapiedra, Esther, Varela, Carmen, García, Ana Belén, Rabal, Obdulia, Oyarzabal, Julen, Bischoff, James R., Klett, Javier, Albarrán, María Isabel, Cebriá, Antonio, Ajenjo, Nuria, García-Serelde, Beatriz, Gómez-Casero, Elena, Cuadrado-Urbano, Manuel, Cebrián, David, Blanco-Aparicio, Carmen, Pastor, Joaquín
Published in European journal of medicinal chemistry (15.04.2019)
Published in European journal of medicinal chemistry (15.04.2019)
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Generation of tricyclic imidazo[1,2-a]pyrazines as novel PI3K inhibitors by application of a conformational restriction strategy
Martínez González, Sonia, Rodríguez-Arístegui, Sonsoles, Hernández, Ana Isabel, Varela, Carmen, González Cantalapiedra, Esther, Álvarez, Rosa María, Rodríguez Hergueta, Antonio, Bischoff, James R., Albarrán, María Isabel, Cebriá, Antonio, Cendón, Elena, Cebrián, David, Alfonso, Patricia, Pastor, Joaquín
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
Published in Bioorganic & medicinal chemistry letters (01.06.2017)
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P846: GENERATION OF A FIRST‐IN‐CLASS INHIBITOR FOR THE MASTER ONCOREGULATOR HNRNP K IN HAEMATOLOGICAL MALIGNANCIES
Otero‐Sobrino, Álvaro, Le Coq, Johanne, Aguilar‐Garrido, Pedro, Aguadero, Miguel Ángel Navarro, Hernández‐Sánchez, María, Isabel Albarrán, María, Klett, Javier, Blanco, Carmen, Fernández Leiro, Rafael, Martinez‐Lopez, Joaquín, Velasco Estevez, Maria, Gallardo, Miguel
Published in HemaSphere (08.08.2023)
Published in HemaSphere (08.08.2023)
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Biological characterization of ETP-46321 a selective and efficacious inhibitor of phosphoinositide-3-kinases
Granda, Teresa G., Cebrián, David, Martínez, Sonia, Anguita, Patricia Villanueva, López, Estela Casas, Link, Wolfgang, Merino, Teresa, Pastor, Joaquín, Serelde, Beatriz G., Peregrina, Sandra, Palacios, Irene, Albarran, Maria Isabel, Cebriá, Antonio, Lorenzo, Milagros, Alonso, Patricia, Fominaya, Jesús, López, Ana Rodríguez, Bischoff, James R.
Published in Investigational new drugs (01.02.2013)
Published in Investigational new drugs (01.02.2013)
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Abstract 4337: Novel potent and selective orally available CDK8/19 kinase inhibitors
Blanco Aparicio, Carmen, Renner, Oliver, Gomez-Casero, Elena, Albarran, Maria Isabel, Cebria, Antonio, Barrera, Borja, Aguirre, Enara, Rodriguez de Miguel, Maria del Carmen, Urbano, Manuel, Hernandez, Ana Isabel, Gomez de la Oliva, Cristina, Rivero, Virginia, Riesco, Rosario Concepcion, Martinez Gonzalez, Sonia, Pastor, Joaquin
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Year of Publication 20.06.2024
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Year of Publication 20.06.2024
Patent
IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
BLANCO APARICIO, Carmen, PASTOR FERNÁNDEZ, Joaquín, RODRÍGUEZ ARÍSTEGUI, Sonsoles, CEBRIÁ GÓMEZ, Antonio, GÓMEZ DE LA OLIVA, Cristina Ana, ALBARRÁN SANTIÑO, María Isabel, MALUMBRES MARTÍNEZ, Marcos, GARCÍA GARCÍA, Ana Belén, MARTÍNEZ GONZÁLEZ, Sonia
Year of Publication 07.02.2024
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Year of Publication 07.02.2024
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BLANCO APARICIO, Carmen, CEBRIÁ GÓMEZ, Antonio, ALBARRÁN SANTIÑO, María Isabel, ÁLVAREZ ESCOBAR, Rosa María, MARTÍN HERNANDO, Jose Ignacio, RIESCO FAGUNDO, Rosario Concepción, GARCÍA GARCÍA, Ana Belén, GONZÁLEZ CANTALAPIEDRA, Esther, HERNÁNDEZ ENCINAS, Elena, RAMOS LIMA, Francisco Javier, GÓMEZ DE LA OLIVA, Cristina Ana, FERNÁNDEZ, Joaquin Pastor, CEBRIÁN MUÑOZ, David Álvaro, MARTÍNEZ GONZÁLEZ, Sonia
Year of Publication 04.07.2024
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Year of Publication 04.07.2024
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IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
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Year of Publication 29.09.2022
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Year of Publication 29.09.2022
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IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
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Year of Publication 29.09.2022
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Year of Publication 29.09.2022
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IMIDAZO[1,2-B]PYRIDAZINE BASED TRICYCLIC COMPOUNDS AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
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Year of Publication 28.09.2022
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Year of Publication 28.09.2022
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IMIDAZO[1,2-A]PYRAZINES AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
GONZÁLEZ CANTALAPIEDRA, Esther, PASTOR FERNÁNDEZ, Joaquín, CEBRIÁ GÓMEZ, Antonio, PASTOR FERNÁNDEZ, Miryam, BLANCO-APARICIO, Carmen, ALBARRÁN SANTIÑO, María Isabel, MALUMBRES MARTÍNEZ, Marcos, GARCÍA GARCÍA, Ana Belén, MARTÍNEZ GONZÁLEZ, Sonia, HERNÁNDEZ HIGUERAS, Ana Isabel
Year of Publication 01.09.2022
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Year of Publication 01.09.2022
Patent
IMIDAZO[1,2-A]PYRAZINES AS INHIBITORS OF HASPIN AND THERAPEUTIC USES THEREOF
GONZÁLEZ CANTALAPIEDRA, Esther, PASTOR FERNÁNDEZ, Joaquín, CEBRIÁ GÓMEZ, Antonio, PASTOR FERNÁNDEZ, Miryam, BLANCO-APARICIO, Carmen, ALBARRÁN SANTIÑO, María Isabel, GARCÍA GARCÍA, Ana Belén, MARTÍNEZ GONZÁLEZ, Sonia, HERNÁNDEZ HIGUERAS, Ana Isabel
Year of Publication 31.08.2022
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Year of Publication 31.08.2022
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COMPOUNDS
GONZALEZ CANTALAPIEDRA, ESTHER, ALVAREZ ESCOBAR, ROSA MARIA, CEBRIAN MUNOZ, DAVID ALVARO, MARTIN HERNANDO, JOSE IGNACIO, FERNANDEZ, JOAQUIN PASTOR, MARTINEZ GONZALEZ, SONIA, ALBARRAN SANTINO, MARIA ISABEL, CEBRIA GOMEZ, ANTONIO, RIESCO FAGUNDO, ROSARIO CONCEPCION, RAMOS LIMA, FRANCISCO JAVIER, BLANCO APARICIO, CARMEN, GARCIA GARCIA, ANA BELEN, GOMEZ DE LA OLIVA, CRISTINA ANA, HERNANDEZ ENCINAS, ELENA
Year of Publication 08.06.2023
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Year of Publication 08.06.2023
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COMPOUNDS
BLANCO APARICIO, Carmen, CEBRIÁ GÓMEZ, Antonio, ALBARRÁN SANTIÑO, María Isabel, ÁLVAREZ ESCOBAR, Rosa María, MARTÍN HERNANDO, Jose Ignacio, RIESCO FAGUNDO, Rosario Concepción, GARCÍA GARCÍA, Ana Belén, GONZÁLEZ CANTALAPIEDRA, Esther, HERNÁNDEZ ENCINAS, Elena, RAMOS LIMA, Francisco Javier, GÓMEZ DE LA OLIVA, Cristina Ana, FERNÁNDEZ, Joaquin Pastor, CEBRIÁN MUÑOZ, David Álvaro, MARTÍNEZ GONZÁLEZ, Sonia
Year of Publication 08.06.2023
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Year of Publication 08.06.2023
Patent