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Ragotte, Robert J., Pulido, David, Lias, Amelia M., Quinkert, Doris, Alanine, Daniel G. W., Jamwal, Abhishek, Davies, Hannah, Nacer, Adéla, Lowe, Edward D., Grime, Geoffrey W., Illingworth, Joseph J., Donat, Robert F., Garman, Elspeth F., Bowyer, Paul W., Higgins, Matthew K., Draper, Simon J.
Published in Nature communications (17.02.2022)
Published in Nature communications (17.02.2022)
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A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates
Douglas, Alexander D., Baldeviano, G. Christian, Jin, Jing, Miura, Kazutoyo, Diouf, Ababacar, Zenonos, Zenon A., Ventocilla, Julio A., Silk, Sarah E., Marshall, Jennifer M., Alanine, Daniel G. W., Wang, Chuan, Edwards, Nick J., Leiva, Karina P., Gomez-Puerta, Luis A., Lucas, Carmen M., Wright, Gavin J., Long, Carole A., Royal, Joseph M., Draper, Simon J.
Published in Nature communications (26.04.2019)
Published in Nature communications (26.04.2019)
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Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5
Douglas, Alexander D, Williams, Andrew R, Knuepfer, Ellen, Illingworth, Joseph J, Furze, Julie M, Crosnier, Cécile, Choudhary, Prateek, Bustamante, Leyla Y, Zakutansky, Sara E, Awuah, Dennis K, Alanine, Daniel G W, Theron, Michel, Worth, Andrew, Shimkets, Richard, Rayner, Julian C, Holder, Anthony A, Wright, Gavin J, Draper, Simon J
Published in The Journal of immunology (1950) (01.01.2014)
Published in The Journal of immunology (1950) (01.01.2014)
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Use of humanised rat basophilic leukaemia cell line RS-ATL8 for the assessment of allergenicity of Schistosoma mansoni proteins
Wan, Daniel, Ludolf, Fernanda, Alanine, Daniel G W, Stretton, Owen, Ali Ali, Eman, Al-Barwary, Nafal, Wang, Xiaowei, Doenhoff, Michael J, Mari, Adriano, Fitzsimmons, Colin M, Dunne, David W, Nakamura, Ryosuke, Oliveira, Guilherme C, Alcocer, Marcos J C, Falcone, Franco H
Published in PLoS neglected tropical diseases (01.09.2014)
Published in PLoS neglected tropical diseases (01.09.2014)
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Characterization of human FcεRIα chain expression and gene copy number in humanized rat basophilic leukaemia (RBL) reporter cell lines
Ali, Eman Ali, Kalli, Marina, Wan, Daniel, Nakamura, Ryosuke, Onion, David, Alanine, Daniel G W, Alcocer, Marcos J C, Falcone, Franco H
Published in PloS one (20.08.2019)
Published in PloS one (20.08.2019)
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Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system
Hjerrild, Kathryn A., Jin, Jing, Wright, Katherine E., Brown, Rebecca E., Marshall, Jennifer M., Labbé, Geneviève M., Silk, Sarah E., Cherry, Catherine J., Clemmensen, Stine B., Jørgensen, Thomas, Illingworth, Joseph J., Alanine, Daniel G. W., Milne, Kathryn H., Ashfield, Rebecca, de Jongh, Willem A., Douglas, Alexander D., Higgins, Matthew K., Draper, Simon J.
Published in Scientific reports (26.07.2016)
Published in Scientific reports (26.07.2016)
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Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo
Foquet, Lander, Schafer, Carola, Minkah, Nana K, Alanine, Daniel G W, Flannery, Erika L, Steel, Ryan W J, Sack, Brandon K, Camargo, Nelly, Fishbaugher, Matthew, Betz, Will, Nguyen, Thao, Billman, Zachary P, Wilson, Elizabeth M, Bial, John, Murphy, Sean C, Draper, Simon J, Mikolajczak, Sebastian A, Kappe, Stefan H I
Published in Frontiers in immunology (14.03.2018)
Published in Frontiers in immunology (14.03.2018)
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Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody
Rawlinson, Thomas. A., Barber, Natalie M., Mohring, Franziska, Cho, Jee Sun, Kosaisavee, Varakorn, Gérard, Samuel F., Alanine, Daniel G. W., Labbé, Geneviève M., Elias, Sean C., Silk, Sarah E., Quinkert, Doris, Jin, Jing, Marshall, Jennifer M., Payne, Ruth O., Minassian, Angela M., Russell, Bruce, Rénia, Laurent, Nosten, François H., Moon, Robert W., Higgins, Matthew K., Draper, Simon J.
Published in Nature microbiology (01.09.2019)
Published in Nature microbiology (01.09.2019)
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Combining Viral Vectored and Protein-in-adjuvant Vaccines Against the Blood-stage Malaria Antigen AMA1: Report on a Phase 1a Clinical Trial
Hodgson, Susanne H, Choudhary, Prateek, Elias, Sean C, Milne, Kathryn H, Rampling, Thomas W, Biswas, Sumi, Poulton, Ian D, Miura, Kazutoyo, Douglas, Alexander D, Alanine, Daniel GW, Illingworth, Joseph J, de Cassan, Simone C, Zhu, Daming, Nicosia, Alfredo, Long, Carole A, Moyle, Sarah, Berrie, Eleanor, Lawrie, Alison M, Wu, Yimin, Ellis, Ruth D, Hill, Adrian V S, Draper, Simon J
Published in Molecular therapy (01.12.2014)
Published in Molecular therapy (01.12.2014)
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Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies
Alanine, Daniel G.W., Quinkert, Doris, Kumarasingha, Rasika, Mehmood, Shahid, Donnellan, Francesca R., Minkah, Nana K., Dadonaite, Bernadeta, Diouf, Ababacar, Galaway, Francis, Silk, Sarah E., Jamwal, Abhishek, Marshall, Jennifer M., Miura, Kazutoyo, Foquet, Lander, Elias, Sean C., Labbé, Geneviève M., Douglas, Alexander D., Jin, Jing, Payne, Ruth O., Illingworth, Joseph J., Pattinson, David J., Pulido, David, Williams, Barnabas G., de Jongh, Willem A., Wright, Gavin J., Kappe, Stefan H.I., Robinson, Carol V., Long, Carole A., Crabb, Brendan S., Gilson, Paul R., Higgins, Matthew K., Draper, Simon J.
Published in Cell (27.06.2019)
Published in Cell (27.06.2019)
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Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex
Williams, Barnabas G., King, Lloyd D. W., Pulido, David, Quinkert, Doris, Lias, Amelia M., Silk, Sarah E., Ragotte, Robert J., Davies, Hannah, Barrett, Jordan R., McHugh, Kirsty, Rigby, Cassandra A., Alanine, Daniel G. W., Barfod, Lea, Shea, Michael W., Cowley, Li An, Dabbs, Rebecca A., Pattinson, David J., Douglas, Alexander D., Lyth, Oliver R., Illingworth, Joseph J., Jin, Jing, Carnrot, Cecilia, Kotraiah, Vinayaka, Christen, Jayne M., Noe, Amy R., MacGill, Randall S., King, C. Richter, Birkett, Ashley J., Soisson, Lorraine A., Skinner, Katherine, Miura, Kazutoyo, Long, Carole A., Higgins, Matthew K., Draper, Simon J.
Published in Nature communications (07.06.2024)
Published in Nature communications (07.06.2024)
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Functional Characterization and Comparison of Plasmodium falciparum Proteins as Targets of Transmission-blocking Antibodies
Nikolaeva, Daria, Illingworth, Joseph J., Miura, Kazutoyo, Alanine, Daniel G.W., Brian, Iona J., Li, Yuanyuan, Fyfe, Alex J., Da, Dari F., Cohuet, Anna, Long, Carole A., Draper, Simon J., Biswas, Sumi
Published in Molecular & cellular proteomics (01.01.2020)
Published in Molecular & cellular proteomics (01.01.2020)
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A PfRH5-Based Vaccine Is Efficacious against Heterologous Strain Blood-Stage Plasmodium falciparum Infection in Aotus Monkeys
Douglas, Alexander D., Baldeviano, G. Christian, Lucas, Carmen M., Lugo-Roman, Luis A., Crosnier, Cécile, Bartholdson, S. Josefin, Diouf, Ababacar, Miura, Kazutoyo, Lambert, Lynn E., Ventocilla, Julio A., Leiva, Karina P., Milne, Kathryn H., Illingworth, Joseph J., Spencer, Alexandra J., Hjerrild, Kathryn A., Alanine, Daniel G.W., Turner, Alison V., Moorhead, Jeromy T., Edgel, Kimberly A., Wu, Yimin, Long, Carole A., Wright, Gavin J., Lescano, Andrés G., Draper, Simon J.
Published in Cell host & microbe (14.01.2015)
Published in Cell host & microbe (14.01.2015)
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Antibodies from malaria-exposed Malians generally interact additively or synergistically with human vaccine-induced RH5 antibodies
Willcox, Alexandra C., Huber, Alex S., Diouf, Ababacar, Barrett, Jordan R., Silk, Sarah E., Pulido, David, King, Lloyd D.W., Alanine, Daniel G.W., Minassian, Angela M., Diakite, Mahamadou, Draper, Simon J., Long, Carole A., Miura, Kazutoyo
Published in Cell reports. Medicine (20.07.2021)
Published in Cell reports. Medicine (20.07.2021)
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Characterization of human Fc[epsilon]RI[alpha] chain expression and gene copy number in humanized rat basophilic leukaemia reporter cell lines
Ali, Eman Ali, Kalli, Marina, Wan, Daniel, Nakamura, Ryosuke, Onion, David, Alanine, Daniel G. W, Alcocer, Marcos J. C, Falcone, Franco H
Published in PloS one (20.08.2019)
Published in PloS one (20.08.2019)
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Characterization of human Fc[epsilon]RI[alpha] chain expression and gene copy number in humanized rat basophilic leukaemia
Ali, Eman Ali, Kalli, Marina, Wan, Daniel, Nakamura, Ryosuke, Onion, David, Alanine, Daniel G. W, Alcocer, Marcos J. C, Falcone, Franco H
Published in PloS one (20.08.2019)
Published in PloS one (20.08.2019)
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Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions
Payne, Ruth O, Silk, Sarah E, Elias, Sean C, Miura, Kazutoyo, Diouf, Ababacar, Galaway, Francis, de Graaf, Hans, Brendish, Nathan J, Poulton, Ian D, Griffiths, Oliver J, Edwards, Nick J, Jin, Jing, Labbé, Geneviève M, Alanine, Daniel Gw, Siani, Loredana, Di Marco, Stefania, Roberts, Rachel, Green, Nicky, Berrie, Eleanor, Ishizuka, Andrew S, Nielsen, Carolyn M, Bardelli, Martino, Partey, Frederica D, Ofori, Michael F, Barfod, Lea, Wambua, Juliana, Murungi, Linda M, Osier, Faith H, Biswas, Sumi, McCarthy, James S, Minassian, Angela M, Ashfield, Rebecca, Viebig, Nicola K, Nugent, Fay L, Douglas, Alexander D, Vekemans, Johan, Wright, Gavin J, Faust, Saul N, Hill, Adrian Vs, Long, Carole A, Lawrie, Alison M, Draper, Simon J
Published in JCI insight (02.11.2017)
Published in JCI insight (02.11.2017)
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Functional Characterization and Comparison of Plasmodium falciparum Proteins as Targets of Transmission-blocking Antibodies
Nikolaeva, Daria, Illingworth, Joseph J, Miura, Kazutoyo, Alanine, Daniel G W, Brian, Iona J, Li, Yuanyuan, Fyfe, Alex J, Da, Dari F, Cohuet, Anna, Long, Carole A, Draper, Simon J, Biswas, Sumi
Published in Molecular & cellular proteomics (01.01.2020)
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Published in Molecular & cellular proteomics (01.01.2020)
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Use of Humanised Rat Basophilic Leukaemia Cell Line RS-ATL8 for the Assessment of Allergenicity of Schistosoma mansoni Proteins: e3124
Wan, Daniel, Ludolf, Fernanda, Alanine, Daniel GW, Stretton, Owen, Ali, Eman Ali, Al-Barwary, Nafal, Wang, Xiaowei, Doenhoff, Michael J, Mari, Adriano, Fitzsimmons, Colin M, Dunne, David W, Nakamura, Ryosuke, Oliveira, Guilherme C, Alcocer, Marcos JC, Falcone, Franco H
Published in PLoS neglected tropical diseases (01.09.2014)
Published in PLoS neglected tropical diseases (01.09.2014)
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