Pharmacokinetics, metabolism, and excretion of [14C]axitinib, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in humans
Smith, Bill J, Pithavala, Yazdi, Bu, Hai-Zhi, Kang, Ping, Hee, Brian, Deese, Alan J, Pool, William F, Klamerus, Karen J, Wu, Ellen Y, Dalvie, Deepak K
Published in Drug metabolism and disposition (01.05.2014)
Published in Drug metabolism and disposition (01.05.2014)
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Journal Article
Significant Species Difference in Amide Hydrolysis of GDC-0834, a Novel Potent and Selective Bruton's Tyrosine Kinase Inhibitor
LICHUAN LIU, HALLADAY, Jason S, KUEBLER, Peter, DAVIS, John C, CHARLENE LIAO, X, LUBACH, Joseph W, DEESE, Alan, SOWELL, C. Gregory, CURRIE, Kevin S, YOUNG, Wendy B, KHOJASTEH, S. Cyrus, HOP, Cornelis E. C. A, SHIN, Young, WONG, Harvey, WONG, Susan, CORAGGIO, Melis, LA, Hank, BAUMGARDNER, Matthew, LE, Hoa, GOPAUL, Sashi, BOGGS, Jason
Published in Drug metabolism and disposition (01.10.2011)
Published in Drug metabolism and disposition (01.10.2011)
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Journal Article
Identification of a Novel Glutathione Conjugate of Flutamide in Incubations with Human Liver Microsomes
Kang, Ping, Dalvie, Deepak, Smith, Evan, Zhou, Sue, Deese, Alan
Published in Drug metabolism and disposition (01.07.2007)
Published in Drug metabolism and disposition (01.07.2007)
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Journal Article
HUMAN IN VITRO GLUTATHIONYL AND PROTEIN ADDUCTS OF CARBAMAZEPINE-10,11-EPOXIDE, A STABLE AND PHARMACOLOGICALLY ACTIVE METABOLITE OF CARBAMAZEPINE
Bu, Hai-Zhi, Kang, Ping, Deese, Alan J, Zhao, Ping, Pool, William F
Published in Drug metabolism and disposition (01.12.2005)
Published in Drug metabolism and disposition (01.12.2005)
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Journal Article
Synthesis of Akt Inhibitor Ipatasertib. Part 2. Total Synthesis and First Kilogram Scale-up
Remarchuk, Travis, St-Jean, Frederic, Carrera, Diane, Savage, Scott, Yajima, Herbert, Wong, Brian, Babu, Srinivasan, Deese, Alan, Stults, Jeffrey, Dong, Michael W, Askin, David, Lane, Jonathan W, Spencer, Keith L
Published in Organic process research & development (19.12.2014)
Published in Organic process research & development (19.12.2014)
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Journal Article
Chemoselective sp 2-sp 3 Cross-Couplings: Iron-Catalyzed Alkyl Transfer to Dihaloaromatics
Malhotra, Sushant, Seng, Pamela S, Koenig, Stefan G, Deese, Alan J, Ford, Kevin A
Published in Organic letters (19.07.2013)
Published in Organic letters (19.07.2013)
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Strategies for the analysis of highly reactive pinacolboronate esters
Zhong, Qiqing, Ngim, Kenley K., Sun, Megan, Li, Jane, Deese, Alan, Chetwyn, Nik P.
Published in Journal of Chromatography A (16.03.2012)
Published in Journal of Chromatography A (16.03.2012)
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Journal Article
Bioactivation of Flutamide Metabolites by Human Liver Microsomes
PING KANG, DALVIE, Deepak, SMITH, Evan, ZHOU, Sue, DEESE, Alan, NIEMAN, James A
Published in Drug metabolism and disposition (01.07.2008)
Published in Drug metabolism and disposition (01.07.2008)
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Journal Article
An isolable acyclic hemiacetal of ansamitocin P-3
Segraves, Nathaniel L., Yazzie, Derrick, Deese, Alan J.
Published in Magnetic resonance in chemistry (01.03.2012)
Published in Magnetic resonance in chemistry (01.03.2012)
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Journal Article
Chemoselective sp2-sp3 cross-couplings: iron-catalyzed alkyl transfer to dihaloaromatics
Malhotra, Sushant, Seng, Pamela S, Koenig, Stefan G, Deese, Alan J, Ford, Kevin A
Published in Organic letters (19.07.2013)
Published in Organic letters (19.07.2013)
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Journal Article
NMR of biofluids and pattern recognition: assessing the impact of NMR parameters on the principal component analysis of urine from rat and mouse
Potts, Barbara C.M, Deese, Alan J, Stevens, Gregory J, Reily, Michael D, Robertson, Donald G, Theiss, Jeffrey
Published in Journal of pharmaceutical and biomedical analysis (01.10.2001)
Published in Journal of pharmaceutical and biomedical analysis (01.10.2001)
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Journal Article
Chemoselective sp(2)-sp(3) Cross-Couplings: Iron-Catalyzed Alkyl Transfer to Dihaloaromatics
Malhotra, Sushant, Seng, Pamela S., Koenig, Stefan G., Deese, Alan J., Ford, Kevin A.
Published in Organic letters (19.07.2013)
Published in Organic letters (19.07.2013)
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Journal Article
Elucidating the structure and cytochrome P450-mediated mechanism for novel metabolites of GDC-0575 in rats
Zhang, Chenghong, Cho, Sungjoon, Napolitano, José G., Russell, David, Gu, Christine, Deese, Alan, Han, Chong, Chen, Yuan, Ma, Shuguang
Published in Xenobiotica (04.03.2022)
Published in Xenobiotica (04.03.2022)
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Journal Article
Absorption, metabolism and excretion of pictilisib, a potent pan-class I phosphatidylinositol-3-Kinase (PI3K) inhibitor, in rats, dogs, and humans
Yue, Qin, Khojasteh, S. Cyrus, Cho, Sungjoon, Ma, Shuguang, Mulder, Teresa, Chen, John, Pang, Jodie, Ding, Xiao, Deese, Alan, Pellet, Jackson D., Siebers, Nicholas, Joas, Lori, Salphati, Laurent, Ware, Joseph A.
Published in Xenobiotica (03.07.2021)
Published in Xenobiotica (03.07.2021)
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Journal Article
Development of an Expedient Process for the Multi-Kilogram Synthesis of Chk1 Inhibitor GDC-0425
Stumpf, Andreas, Cheng, Zhigang Ken, Wong, Brian, Reynolds, Mark, Angelaud, Remy, Girotti, James, Deese, Alan, Gu, Christine, Gazzard, Lewis
Published in Organic process research & development (19.06.2015)
Published in Organic process research & development (19.06.2015)
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Journal Article
Characterizing the in vitro species differences in N-glucuronidation of a potent pan-PIM inhibitor GNE-924 containing a 3,5-substituted 6-azaindazole
Lin, Molly, Ly, Justin, Takahashi, Ryan, Chen, John, Deese, Alan, Robinson, Sarah J., Kolesnikov, Aleksandr, Wong, Susan, Wang, Xiaojing, Chang, Jae H.
Published in Xenobiotica (03.10.2018)
Published in Xenobiotica (03.10.2018)
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Journal Article
Solid-State Characterization of Novel Propylene Glycol Ester Solvates Isolated from Lipid Formulations
Chakravarty, Paroma, Kothari, Sanjeev, Deese, Alan, Lubach, Joseph W
Published in Molecular pharmaceutics (06.07.2015)
Published in Molecular pharmaceutics (06.07.2015)
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