A Randomized, Placebo‐Controlled Phase III Extension Trial of the Long‐Term Safety and Tolerability of Anifrolumab in Active Systemic Lupus Erythematosus
Kalunian, Kenneth C., Furie, Richard, Morand, Eric F., Bruce, Ian N., Manzi, Susan, Tanaka, Yoshiya, Winthrop, Kevin, Hupka, Ihor, Zhang, Lijin (Jinny), Werther, Shanti, Abreu, Gabriel, Hultquist, Micki, Tummala, Raj, Lindholm, Catharina, Al‐Mossawi, Hussein
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2023)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2023)
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Journal Article
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
Penkava, Frank, Velasco-Herrera, Martin Del Castillo, Young, Matthew D., Yager, Nicole, Nwosu, Lilian N., Pratt, Arthur G., Lara, Alicia Lledo, Guzzo, Charlotte, Maroof, Ash, Mamanova, Lira, Cole, Suzanne, Efremova, Mirjana, Simone, Davide, Filer, Andrew, Brown, Chrysothemis C., Croxford, Andrew L., Isaacs, John D., Teichmann, Sarah, Bowness, Paul, Behjati, Sam, Hussein Al-Mossawi, M.
Published in Nature communications (21.09.2020)
Published in Nature communications (21.09.2020)
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Journal Article
Single cell analysis of spondyloarthritis regulatory T cells identifies distinct synovial gene expression patterns and clonal fates
Simone, Davide, Penkava, Frank, Ridley, Anna, Sansom, Stephen, Al-Mossawi, M. Hussein, Bowness, Paul
Published in Communications biology (14.12.2021)
Published in Communications biology (14.12.2021)
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Journal Article
Peripheral CD8+ T cell characteristics associated with durable responses to immune checkpoint blockade in patients with metastatic melanoma
Fairfax, Benjamin P., Taylor, Chelsea A., Watson, Robert A., Nassiri, Isar, Danielli, Sara, Fang, Hai, Mahé, Elise A., Cooper, Rosalin, Woodcock, Victoria, Traill, Zoe, Al-Mossawi, M. Hussein, Knight, Julian C., Klenerman, Paul, Payne, Miranda, Middleton, Mark R.
Published in Nature medicine (01.02.2020)
Published in Nature medicine (01.02.2020)
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Journal Article
CBP30, a selective CBP/p300 bromodomain inhibitor, suppresses human Th17 responses
Hammitzsch, Ariane, Tallant, Cynthia, Fedorov, Oleg, O’Mahony, Alison, Brennan, Paul E., Hay, Duncan A., Martinez, Fernando O., Al-Mossawi, M. Hussein, de Wit, Jelle, Vecellio, Matteo, Wells, Christopher, Wordsworth, Paul, Müller, Susanne, Knapp, Stefan, Bowness, Paul
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (25.08.2015)
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Journal Article
Progress in our understanding of the pathogenesis of ankylosing spondylitis
Simone, Davide, Al Mossawi, M Hussein, Bowness, Paul
Published in Rheumatology (Oxford, England) (01.11.2018)
Published in Rheumatology (Oxford, England) (01.11.2018)
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Journal Article
Inhibiting ex-vivo Th17 responses in Ankylosing Spondylitis by targeting Janus kinases
Hammitzsch, Ariane, Chen, Liye, de Wit, Jelle, Al-Mossawi, M. Hussein, Ridley, Anna, Sekine, Takuya, Simone, Davide, Doig, Karen, Skapenko, Alla, Bowness, Paul
Published in Scientific reports (23.10.2018)
Published in Scientific reports (23.10.2018)
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Journal Article
Multi-omic single cell analysis resolves novel stromal cell populations in healthy and diseased human tendon
Kendal, Adrian R., Layton, Thomas, Al-Mossawi, Hussein, Appleton, Louise, Dakin, Stephanie, Brown, Rick, Loizou, Constantinos, Rogers, Mark, Sharp, Robert, Carr, Andrew
Published in Scientific reports (03.09.2020)
Published in Scientific reports (03.09.2020)
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Journal Article
Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis
Ridley, Anna, Hatano, Hiroko, Wong‐Baeza, Isabel, Shaw, Jacqueline, Matthews, Katherine K., Al‐Mossawi, Hussein, Ladell, Kristin, Price, David A., Bowness, Paul, Kollnberger, Simon
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2016)
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Journal Article
Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele
Al-Mossawi, Hussein, Yager, Nicole, Taylor, Chelsea A., Lau, Evelyn, Danielli, Sara, de Wit, Jelle, Gilchrist, James, Nassiri, Isar, Mahe, Elise A., Lee, Wanseon, Rizvi, Laila, Makino, Seiko, Cheeseman, Jane, Neville, Matt, Knight, Julian C., Bowness, Paul, Fairfax, Benjamin P.
Published in Nature communications (08.10.2019)
Published in Nature communications (08.10.2019)
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Journal Article
Progress in our understanding of the pathogenesis of ankylosing spondylitis
Simone, Davide, Al Mossawi, M Hussein, Bowness, Paul
Published in Rheumatology (Oxford, England) (01.11.2018)
Published in Rheumatology (Oxford, England) (01.11.2018)
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Journal Article
LBO1 DORIS remission in patients with SLE treated with anifrolumab or placebo during the 4-year TULIP-LTE trial: post hoc analysis
Vollenhoven, Ronald van, Morand, Eric, Furie, Richard, Kalunian, Kenneth, Tummala, Raj, Abreu, Gabriel, Al-Mossawi, Hussein, Lindholm, Catharina
Published in Lupus science & medicine (14.03.2024)
Published in Lupus science & medicine (14.03.2024)
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Journal Article
Persistent stromal fibroblast activation is present in chronic tendinopathy
Dakin, Stephanie G, Buckley, Christopher D, Al-Mossawi, Mohammad Hussein, Hedley, Robert, Martinez, Fernando O, Wheway, Kim, Watkins, Bridget, Carr, Andrew J
Published in Arthritis research & therapy (25.01.2017)
Published in Arthritis research & therapy (25.01.2017)
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Journal Article
Optimising psoriatic arthritis therapy with immunological methods to increase standard evaluation: the protocol of an open-label multicentre, parallel-group, two-arm randomised controlled study evaluation precision medicine approach in the treatment of psoriatic arthritis
Ooms, Alexander, Al-Mossawi, Hussein, Bennett, Louise, Bogale, Mimi, Bowness, Paul, Francis, Anne, Goodyear, Carl, Kirkham, Bruce W, Lalnunhlimi, Sylvine, McInnes, Iain B, Richards, Duncan, Siebert, Stefan, Taams, Leonie S, Tulunay Virlan, Aysin, Yager, Nicole, Coates, Laura C
Published in BMJ open (28.09.2023)
Published in BMJ open (28.09.2023)
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Journal Article
Treating to target in psoriatic arthritis: assessing real-world outcomes and optimising therapeutic strategy for adults with psoriatic arthritis-study protocol for the MONITOR-PsA study, a trials within cohorts study design
Rombach, Ines, Tillett, William, Jadon, Deepak, Tucker, Laura, Watson, Marion, Francis, Anne, Sinomati, Yvonne, Eldridge, Lucy, Dritsaki, Melina, Dutton, Susan J, Al-Mossawi, Hussein, Gullick, Nicola, Thompson, Ben, Coates, Laura C
Published in Current controlled trials in cardiovascular medicine (04.03.2021)
Published in Current controlled trials in cardiovascular medicine (04.03.2021)
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Journal Article
Correction: Targeting DORIS Remission and LLDAS in SLE: A Review
Parra Sánchez, Agner R., van Vollenhoven, Ronald F., Morand, Eric F., Bruce, Ian N., Kandane-Rathnayake, Rangi, Weiss, Gudrun, Tummala, Raj, Al-Mossawi, Hussein, Sorrentino, Alessandro
Published in Rheumatology and therapy. (01.08.2024)
Published in Rheumatology and therapy. (01.08.2024)
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Journal Article
1502 Lupus low disease activity state attainment in the phase 3 placebo-controlled TULIP long-term extension trial of anifrolumab
Morand, Eric F, Vollenhoven, Ronald van, Furie, Richard A, Kalunian, Kenneth C, Yavuz, Sule, Abreu, Gabriel, Lindholm, Catharina, Al-Mossawi, Hussein
Published in Lupus science & medicine (16.05.2024)
Published in Lupus science & medicine (16.05.2024)
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Journal Article
Targeting DORIS Remission and LLDAS in SLE: A Review
Parra Sánchez, Agner R., van Vollenhoven, Ronald F., Morand, Eric F., Bruce, Ian N., Kandane-Rathnayake, Rangi, Weiss, Gudrun, Tummala, Raj, Al-Mossawi, Hussein, Sorrentino, Alessandro
Published in Rheumatology and therapy. (01.12.2023)
Published in Rheumatology and therapy. (01.12.2023)
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Journal Article
Novel Therapeutic Targets in Axial Spondyloarthritis
Worth, Claudia, Bowness, Paul, Hussein Al-Mossawi, M.
Published in Current treatment options in rheumatology (2018)
Published in Current treatment options in rheumatology (2018)
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Journal Article
Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply
McHugh, Kirsty, Rysnik, Oliwia, Kollnberger, Simon, Shaw, Jacqueline, Utriainen, Lotta, Al-Mossawi, Mohammad Hussein, Payeli, Sravan, Marroquin, Osiris, Milling, Simon, Renner, Christoph, Bowness, Paul
Published in Annals of the rheumatic diseases (01.04.2014)
Published in Annals of the rheumatic diseases (01.04.2014)
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