Inhibitory Effects of Cranberry Juice and Its Components on Intestinal OATP1A2 and OATP2B1: Identification of Avicularin as a Novel Inhibitor
Morita, Tokio, Akiyoshi, Takeshi, Tsuchitani, Toshiaki, Kataoka, Hiroki, Araki, Naoya, Yajima, Kodai, Katayama, Kazuhiro, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Journal of agricultural and food chemistry (16.03.2022)
Published in Journal of agricultural and food chemistry (16.03.2022)
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Journal Article
Estimation of absolute oral bioavailability without performing an intravenous clinical study
Ohtani, Hisakazu, Iwata, Risa, Imaoka, Ayuko, Akiyoshi, Takeshi
Published in Drug metabolism and pharmacokinetics (01.06.2021)
Published in Drug metabolism and pharmacokinetics (01.06.2021)
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Journal Article
Inhibitory kinetics of fruit components on CYP2C19 activity
Seki, Hiroyuki, Akiyoshi, Takeshi, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.06.2019)
Published in Drug metabolism and pharmacokinetics (01.06.2019)
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Journal Article
Analysis of inhibition kinetics of three beverage ingredients, bergamottin, dihydroxybergamottin and resveratrol, on CYP2C9 activity
Akiyoshi, Takeshi, Uchiyama, Marika, Inada, Rino, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.02.2022)
Published in Drug metabolism and pharmacokinetics (01.02.2022)
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Journal Article
Irinotecan‐induced gastrointestinal damage impairs the absorption of dabigatran etexilate
Hattori, Tomoki, Imaoka, Ayuko, Akiyoshi, Takeshi, Ohtani, Hisakazu
Published in Biopharmaceutics & drug disposition (01.11.2019)
Published in Biopharmaceutics & drug disposition (01.11.2019)
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Journal Article
pH-dependent transport kinetics of the human organic anion-transporting polypeptide 1A2
Morita, Tokio, Akiyoshi, Takeshi, Sato, Ryo, Katayama, Kazuhiro, Yajima, Kodai, Kataoka, Hiroki, Imaoka, Ayuko, Sugimoto, Yoshikazu, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.04.2020)
Published in Drug metabolism and pharmacokinetics (01.04.2020)
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Journal Article
Comparison of the inhibitory properties of the fruit component naringenin and its glycosides against OATP1A2 genetic variants
Araki, Naoya, Morita, Tokio, Akiyoshi, Takeshi, Kataoka, Hiroki, Yajima, Kodai, Katayama, Kazuhiro, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.10.2022)
Published in Drug metabolism and pharmacokinetics (01.10.2022)
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Journal Article
Dual kinetics of OATP2B1: Inhibitory potency and pH-dependence of OATP2B1 inhibitors
Sato, Ryo, Akiyoshi, Takeshi, Morita, Tokio, Katayama, Kazuhiro, Yajima, Kodai, Kataoka, Hiroki, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.12.2021)
Published in Drug metabolism and pharmacokinetics (01.12.2021)
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Journal Article
Comparison of the transport kinetics of fexofenadine and its pH dependency among OATP1A2 genetic variants
Han, Hongye, Akiyoshi, Takeshi, Morita, Tokio, Kataoka, Hiroki, Katayama, Kazuhiro, Yajima, Kodai, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.12.2022)
Published in Drug metabolism and pharmacokinetics (01.12.2022)
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Journal Article
Comparison of the inhibitory effects of azole antifungals on cytochrome P450 3A4 genetic variants
Yamaguchi, Yuki, Akiyoshi, Takeshi, Kawamura, Go, Imaoka, Ayuko, Miyazaki, Mitsue, Guengerich, F. Peter, Nakamura, Katsunori, Yamamoto, Koujirou, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.06.2021)
Published in Drug metabolism and pharmacokinetics (01.06.2021)
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Journal Article
Evaluation of hepatic CYP3A enzyme activity using endogenous markers in lung cancer patients treated with cisplatin, dexamethasone, and aprepitant
Hibino, Hideyuki, Sakiyama, Naomi, Makino, Yoshinori, Makihara-Ando, Reiko, Horinouchi, Hidehito, Fujiwara, Yutaka, Kanda, Shintaro, Goto, Yasushi, Yoshida, Tatsuya, Okuma, Yusuke, Shinno, Yuki, Murakami, Shuji, Hashimoto, Hironobu, Akiyoshi, Takeshi, Imaoka, Ayuko, Ohe, Yuichiro, Yamaguchi, Masakazu, Ohtani, Hisakazu
Published in European journal of clinical pharmacology (01.04.2022)
Published in European journal of clinical pharmacology (01.04.2022)
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Journal Article
5‐Fluorouracil treatment alters the expression of intestinal transporters in rats
Yotsumoto, Keiichi, Akiyoshi, Takeshi, Wada, Naoki, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Biopharmaceutics & drug disposition (01.12.2017)
Published in Biopharmaceutics & drug disposition (01.12.2017)
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Journal Article
Variation in the inhibitory potency of terbinafine among genetic variants of CYP2D6
Akiyoshi, Takeshi, Ishiuchi, Miho, Imaoka, Ayuko, Ohtani, Hisakazu
Published in Drug metabolism and pharmacokinetics (01.08.2015)
Published in Drug metabolism and pharmacokinetics (01.08.2015)
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