The CYP2D6 Humanized Mouse: Effect of the Human CYP2D6 Transgene and HNF4α on the Disposition of Debrisoquine in the Mouse
Corchero, Javier, Granvil, Camille P., Akiyama, Taro E., Hayhurst, Graham P., Pimprale, Satish, Feigenbaum, Lionel, Idle, Jeffrey R., Gonzalez, Frank J.
Published in Molecular pharmacology (01.12.2001)
Published in Molecular pharmacology (01.12.2001)
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Journal Article
Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines
Akiyama, T E, Nicol, C J, Fievet, C, Staels, B, Ward, J M, Auwerx, J, Lee, S S, Gonzalez, F J, Peters, J M
Published in The Journal of biological chemistry (19.10.2001)
Published in The Journal of biological chemistry (19.10.2001)
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Journal Article
Expression profile of MODY3/HNF-1α protein in the developing mouse pancreas
NAMMO, T, YAMAGATA, K, HAMAOKA, R, ZHU, Q, AKIYAMA, T. E, GONZALEZ, F. J, MIYAGAWA, J, MATSUZAWA, Y
Published in Diabetologia (01.08.2002)
Published in Diabetologia (01.08.2002)
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Journal Article
PPARs: therapeutic targets for metabolic disease
Berger, Joel P., Akiyama, Taro E., Meinke, Peter T.
Published in Trends in pharmacological sciences (Regular ed.) (01.05.2005)
Published in Trends in pharmacological sciences (Regular ed.) (01.05.2005)
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Journal Article
PPARγ and PPARδ Negatively Regulate Specific Subsets of Lipopolysaccharide and IFN-γ Target Genes in Macrophages
Welch, John S., Ricote, Mercedes, Akiyama, Taro E., Gonzalez, Frank J., Glass, Christopher K.
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)
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Journal Article
Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor α
CHEUNG, Connie, AKIYAMA, Taro E, WARD, Jerrold M, NICOL, Christopher J, FEIGENBAUM, Lionel, VINSON, Charles, GONZALEZ, Frank J
Published in Cancer research (Chicago, Ill.) (01.06.2004)
Published in Cancer research (Chicago, Ill.) (01.06.2004)
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Journal Article
Conditional Disruption of the Peroxisome Proliferator-Activated Receptor γ Gene in Mice Results in Lowered Expression of ABCA1, ABCG1, and apoE in Macrophages and Reduced Cholesterol Efflux
Akiyama, Taro E., Sakai, Shuichi, Lambert, Gilles, Nicol, Christopher J., Matsusue, Kimihiko, Pimprale, Satish, Lee, Ying-Hue, Ricote, Mercedes, Glass, Christopher K., Brewer, H. Bryan, Gonzalez, Frank J.
Published in Molecular and Cellular Biology (01.04.2002)
Published in Molecular and Cellular Biology (01.04.2002)
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Journal Article
Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver
BRADFORD, Blair U, KONO, Hiroshi, RUSYN, Ivan, ISAYAMA, Fuyumi, KOSYK, Oksana, WHEELER, Michael D, AKIYAMA, Taro E, BLEYE, Lisa, KRAUSZ, Kristopher W, GONZALEZ, Frank J, KOOP, Dennis R
Published in Hepatology (Baltimore, Md.) (01.02.2005)
Published in Hepatology (Baltimore, Md.) (01.02.2005)
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Journal Article
Regulation of P450 genes by liver-enriched transcription factors and nuclear receptors
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Book Review
Journal Article
PPARγ in endothelial cells influences high fat diet-induced hypertension
Nicol, Christopher J., Adachi, Masahiro, Akiyama, Taro E., Gonzalez, Frank J.
Published in American journal of hypertension (01.04.2005)
Published in American journal of hypertension (01.04.2005)
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Journal Article
Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1alpha (HNF1alpha). Alterations in fatty acid homeostasis in HNF1alpha-deficient mice
Akiyama, T E, Ward, J M, Gonzalez, F J
Published in The Journal of biological chemistry (01.09.2000)
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Published in The Journal of biological chemistry (01.09.2000)
Journal Article
Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1α)-deficient mice
Cheung, Connie, Akiyama, Taro E., Kudo, Gen, Gonzalez, Frank J.
Published in Biochemical pharmacology (15.11.2003)
Published in Biochemical pharmacology (15.11.2003)
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Journal Article
Peroxisome proliferator-activated receptor beta/delta regulates very low density lipoprotein production and catabolism in mice on a Western diet
Akiyama, Taro E, Lambert, Gilles, Nicol, Christopher J, Matsusue, Kimihiko, Peters, Jeffrey M, Brewer, Jr, H Bryan, Gonzalez, Frank J
Published in The Journal of biological chemistry (14.05.2004)
Published in The Journal of biological chemistry (14.05.2004)
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Journal Article
Expression profile of MODY3/HNF-1alpha protein in the developing mouse pancreas
Nammo, T, Yamagata, K, Hamaoka, R, Zhu, Q, Akiyama, T E, Gonzalez, F J, Miyagawa, J, Matsuzawa, Y
Published in Diabetologia (01.08.2002)
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Published in Diabetologia (01.08.2002)
Journal Article
On par with PPARs
Akiyama, Taro E, Nicol, Christopher J, Gonzalez, Frank J
Published in Trends in genetics (01.06.2001)
Published in Trends in genetics (01.06.2001)
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Journal Article
Conference Proceeding
Peroxisome Proliferator-activated Receptor β (δ)-dependent Regulation of Ubiquitin C Expression Contributes to Attenuation of Skin Carcinogenesis
Kim, Dae J., Akiyama, Taro E., Harman, Fred S., Burns, Amanda M., Shan, Weiwei, Ward, Jerrold M., Kennett, Mary J., Gonzalez, Frank J., Peters, Jeffrey M.
Published in The Journal of biological chemistry (28.05.2004)
Published in The Journal of biological chemistry (28.05.2004)
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Journal Article