Collaborative Study of Thresholds for Mutagens: Adaptive Responses in the Micronucleus Test and Gene Induction by Mutagenic Treatments
Sutou, Shizuyo, Koeda, Akiko, Komatsu, Kana, Shiragiku, Toshiyuki, Seki, Hiroshi, Kudo, Toshiyuki
Published in Dose-response (01.04.2024)
Published in Dose-response (01.04.2024)
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Collaborative Study of Thresholds for Mutagens: Hormetic Responses in Cell Proliferation Tests Using Human and Murine Lymphoid Cells
Sutou, Shizuyo, Koeda, Akiko, Komatsu, Kana, Shiragiku, Toshiyuki, Seki, Hiroshi, Kudo, Toshiyuki
Published in Dose-response (01.04.2021)
Published in Dose-response (01.04.2021)
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Comparison of the inducibility of CYP mRNA exposed to typical inducers in fresh and cryopreserved cynomolgus monkey hepatocytes
Koeda, Akiko, Iwao, Takahiro, Nakanishi, Anna, Mizuno, Shota, Yamashita, Misaki, Sakai, Yoko, Nakamura, Katsunori, Matsunaga, Tamihide
Published in Drug metabolism and pharmacokinetics (01.06.2020)
Published in Drug metabolism and pharmacokinetics (01.06.2020)
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Journal Article
Comparison of mRNA expression profiles of drug-metabolizing enzymes and transporters in fresh and cryopreserved cynomolgus monkey hepatocytes
Koeda, Akiko, Iwao, Takahiro, Nakanishi, Anna, Mizuno, Shota, Yamashita, Misaki, Sakai, Yoko, Nakamura, Katsunori, Matsunaga, Tamihide
Published in Drug metabolism and pharmacokinetics (01.08.2019)
Published in Drug metabolism and pharmacokinetics (01.08.2019)
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Journal Article
Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
Ohkura, Takako, Ohta, Kunihiro, Nagao, Takuya, Kusumoto, Kumiko, Koeda, Akiko, Ueda, Tadayoshi, Jomura, Tomoko, Ikeya, Takeshi, Ozeki, Emiko, Wada, Kazuki, Naitoh, Kazushi, Inoue, Yukiko, Takahashi, Naoki, Iwai, Hisakazu, Arakawa, Hiroshi, Ogihara, Takuo
Published in Drug metabolism and pharmacokinetics (2014)
Published in Drug metabolism and pharmacokinetics (2014)
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Multisite studies for optimization of a highly efficient culture assay used for in vitro detection of residual undifferentiated human pluripotent stem cells intermingled in cell therapy products
Watanabe, Takeshi, Yasuda, Satoshi, Kusakawa, Shinji, Kuroda, Takuya, Furukawa, Hatsue, Futamura, Mayumi, Shimizu, Shigekazu, Morishita, Akihiko, Hata, Shinko, Koeda, Akiko, Komatsu, Kana, Sato, Yoji
Published in Regenerative therapy (01.06.2024)
Published in Regenerative therapy (01.06.2024)
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Journal Article
Comparison of Inducibility of CYP1A and CYP3A mRNAs by Prototypical Inducers in Primary Cultures of Human, Cynomolgus Monkey, and Rat Hepatocytes
Nishimura, Masuhiro, Koeda, Akiko, Suganuma, Yasuyuki, Suzuki, Emako, Shimizu, Takefumi, Nakayama, Mitsuo, Satoh, Tetsuo, Narimatsu, Shizuo, Naito, Shinsaku
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2007)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2007)
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Discrimination of genotoxic and non-genotoxic hepatocarcinogens by statistical analysis based on gene expression profiling in the mouse liver as determined by quantitative real-time PCR
Watanabe, Takashi, Suzuki, Takayoshi, Natsume, Masakatsu, Nakajima, Madoka, Narumi, Kazunori, Hamada, Shuichi, Sakuma, Tomohiro, Koeda, Akiko, Oshida, Keiyu, Miyamoto, Yohei, Maeda, Akihisa, Hirayama, Michiasa, Sanada, Hisakazu, Honda, Hiroshi, Ohyama, Wakako, Okada, Emiko, Fujiishi, Yohei, Sutou, Shizuyo, Tadakuma, Ayami, Ishikawa, Yasuyoshi, Kido, Mahoko, Minamiguchi, Rina, Hanahara, Izumi, Furihata, Chie
Published in Mutation research (18.09.2012)
Published in Mutation research (18.09.2012)
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Journal Article
Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests
Sutou, Shizuyo, Koeda, Akiko, Komatsu, Kana, Shiragiku, Toshiyuki, Seki, Hiroshi, Yamakage, Kohji, Niitsuma, Takeru, Kudo, Toshiyuki, Wakata, Akihiro
Published in Genes and environment (08.10.2018)
Published in Genes and environment (08.10.2018)
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Journal Article
Tissue-Specific mRNA Expression Profiles of Drug-Metabolizing Enzymes and Transporters in the Cynomolgus Monkey
Nishimura, Masuhiro, Koeda, Akiko, Morikawa, Hiroshi, Satoh, Tetsuo, Narimatsu, Shizuo, Naito, Shinsaku
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2009)
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Journal Article
Comparison of Inducibility of Multidrug Resistance (MDR)1, Multidrug Resistance-Associated Protein (MRP)1, and MRP2 mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes
Nishimura, Masuhiro, Koeda, Akiko, Morikawa, Hiroshi, Satoh, Tetsuo, Narimatsu, Shizuo, Naito, Shinsaku
Published in Biological & Pharmaceutical Bulletin (01.11.2008)
Published in Biological & Pharmaceutical Bulletin (01.11.2008)
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Journal Article
Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes
Hanioka, Nobumitsu, Tanabe, Natsuko, Jinno, Hideto, Tanaka-Kagawa, Toshiko, Nagaoka, Kenjiro, Naito, Shinsaku, Koeda, Akiko, Narimatsu, Shizuo
Published in Life sciences (1973) (14.08.2010)
Published in Life sciences (1973) (14.08.2010)
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Journal Article
Regulation of mRNA Expression of MDR1, MRP1, MRP2 and MRP3 by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Rat Hepatocytes
Nishimura, Masuhiro, Koeda, Akiko, Suzuki, Emako, Kawano, Yuichi, Nakayama, Mitsuo, Satoh, Tetsuo, Narimatsu, Shizuo, Naito, Shinsaku
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2006)
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Journal Article
Comparison of Inducibility of Sulfotransferase and UDP-Glucuronosyltransferase mRNAs by Prototypical Microsomal Enzyme Inducers in Primary Cultures of Human and Cynomolgus Monkey Hepatocytes
Nishimura, Masuhiro, Koeda, Akiko, Shimizu, Takefumi, Nakayama, Mitsuo, Satoh, Tetsuo, Narimatsu, Shizuo, Naito, Shinsaku
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2008)
Published in DRUG METABOLISM AND PHARMACOKINETICS (01.01.2008)
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Journal Article
Genotoxicity studies of 2,6-dinitrotoluene (2,6-DNT)
Suzuki, Hiroshi, Imamura, Tadashi, Koeda, Akiko, Morimoto, Kiyoshi, Wakasa, Yoshio, Takei, Yoshihiro, Amemiya, Rie, Hatakeyama, Hirofumi, Satoh, Hiroshi, Sato, Shin-ichi
Published in Journal of toxicological sciences (2011)
Published in Journal of toxicological sciences (2011)
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Journal Article
Effects of prototypical drug-metabolizing enzyme inducers on mRNA expression of housekeeping genes in primary cultures of human and rat hepatocytes
Nishimura, Masuhiro, Koeda, Akiko, Suzuki, Emako, Shimizu, Takefumi, Kawano, Yuichi, Nakayama, Mitsuo, Satoh, Tetsuo, Narimatsu, Shizuo, Naito, Shinsaku
Published in Biochemical and biophysical research communications (04.08.2006)
Published in Biochemical and biophysical research communications (04.08.2006)
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Stereoselective Glucuronidation of Propranolol in Human and Cynomolgus Monkey Liver Microsomes: Role of Human Hepatic UDP-Glucuronosyltransferase Isoforms, UGT1A9, UGT2B4 and UGT2B7
Hanioka, Nobumitsu, Hayashi, Keiko, Shimizudani, Takeshi, Nagaoka, Kenjiro, Koeda, Akiko, Naito, Shinsaku, Narimatsu, Shizuo
Published in Pharmacology (01.01.2008)
Published in Pharmacology (01.01.2008)
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Journal Article
Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A6 enzymes
Hanioka, Nobumitsu, Takeda, Yuri, Jinno, Hideto, Tanaka-Kagawa, Toshiko, Naito, Shinsaku, Koeda, Akiko, Shimizu, Takefumi, Nomura, Mamoru, Narimatsu, Shizuo
Published in Chemico-biological interactions (01.12.2006)
Published in Chemico-biological interactions (01.12.2006)
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Journal Article
Evaluation of Human Hepatocytes Cultured by Three-dimensional Spheroid Systems for Drug Metabolism
Takako OHKURA, Kunihiro OHTA, Takuya NAGAO, Kumiko KUSUMOTO, Akiko KOEDA, Tadayoshi UEDA, Tomoko JOMURA, Takeshi IKEYA, Emiko OZEKI, Kazuki WADA, Kazushi NAITOH, Yukiko INOUE, Naoki TAKAHASHI, Hisakazu IWAI, Hiroshi ARAKAWA, Takuo OGIHARA
Published in DRUG METABOLISM AND PHARMACOKINETICS (25.10.2014)
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Published in DRUG METABOLISM AND PHARMACOKINETICS (25.10.2014)
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