Mode of action of ethyl tertiary-butyl ether hepatotumorigenicity in the rat: Evidence for a role of oxidative stress via activation of CAR, PXR and PPAR signaling pathways
Kakehashi, Anna, Hagiwara, Akihiro, Imai, Norio, Nagano, Kasuke, Nishimaki, Fukumi, Banton, Marcy, Wei, Min, Fukushima, Shoji, Wanibuchi, Hideki
Published in Toxicology and applied pharmacology (01.12.2013)
Published in Toxicology and applied pharmacology (01.12.2013)
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Promotion of liver and kidney carcinogenesis by ethyl tertiary-butyl ether (ETBE) in male Wistar rats
Hagiwara, Akihiro, Doi, Yuko, Imai, Norio, Suguro, Mayuko, Kawabe, Mayumi, Furukawa, Fumio, Tamano, Seiko, Nagano, Kasuke, Fukushima, Shoji
Published in Journal of Toxicologic Pathology (01.01.2015)
Published in Journal of Toxicologic Pathology (01.01.2015)
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Ninety-day oral toxicity study of rhamsan gum, a natural food thickener produced from Sphingomonas ATCC 31961, in Crl:CD(SD)IGS rats
Hagiwara, Akihiro, Imai, Norio, Doi, Yuko, Sano, Masashi, Tamano, Seiko, Omoto, Toshio, Asai, Iwao, Yasuhara, Kazuo, Hayashi, Shim-mo
Published in Journal of toxicological sciences (01.08.2010)
Published in Journal of toxicological sciences (01.08.2010)
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A 28-day oral toxicity study of fermentation-derived cellulose, produced by Acetobacter aceti subspecies xylinum, in F344 rats
Hagiwara, Akihiro, Imai, Norio, Sano, Masashi, Kawabe, Mayumi, Tamano, Seiko, Kitamura, Satoshi, Omoto, Toshio, Asai, Iwao, Yasuhara, Kazuo, Hayashi, Shim-mo
Published in Journal of toxicological sciences (01.06.2010)
Published in Journal of toxicological sciences (01.06.2010)
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A 90-day oral toxicity study of purple corn color, a natural food colorant, in F344 rats
Nabae, Kyoko, Hayashi, Shim-mo, Kawabe, Mayumi, Ichihara, Toshio, Hagiwara, Akihiro, Tamano, Seiko, Tsushima, Yoko, Uchida, Koji, Koda, Takatoshi, Nakamura, Mikio, Ogawa, Kumiko, Shirai, Tomoyuki
Published in Food and chemical toxicology (01.02.2008)
Published in Food and chemical toxicology (01.02.2008)
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Prevention by natural food anthocyanins, purple sweet potato color and red cabbage color, of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-associated colorectal carcinogenesis in rats initiated with 1,2-dimethylhydrazine
HAGIWARA, Akihiro, YOSHINO, Hiroko, SHIRAI, Tomoyuki, ICHIHARA, Toshio, KAWABE, Mayumi, TAMANO, Seiko, AOKI, Hiromitsu, KODA, Takatoshi, NAKAMURA, Mikio, IMAIDA, Katsumi, ITO, Nobuyuki
Published in Journal of toxicological sciences (01.02.2002)
Published in Journal of toxicological sciences (01.02.2002)
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A twenty eight-day repeated dose toxicity study of black soybean extract in Sprague-Dawley rats
Hagiwara, Akihiro, Imai, Norio, Numano, Takamasa, Nakashima, Hironao, Tamano, Seiko, Sakaue, Kazushi, Tanaka, Kiyofumi, Yasuhara, Kazuo, Hayashi, Shim-mo
Published in Journal of toxicological sciences (2010)
Published in Journal of toxicological sciences (2010)
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No Promoting Effect of Ethyl Tertiary-butyl Ether (ETBE)on Rat Urinary Bladder Carcinogenesis Initiated with N-Butyl-N-(4-hydroxybutyl)nitrosamine
Hagiwara, Akihiro, Imai, Norio, Doi, Yuko, Suguro, Mayuko, Kawabe, Mayumi, Furukawa, Fumio, Nagano, Kasuke, Fukushima, Shoji
Published in Journal of Toxicologic Pathology (01.12.2013)
Published in Journal of Toxicologic Pathology (01.12.2013)
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Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic 1-Nitropropane in F344 Rats
Doi, Yuko, Tamano, Seiko, Kawabe, Mayumi, Sano, Masashi, Imai, Norio, Nakashima, Hironao, Furukawa, Fumio, Hagiwara, Akihiro, Otsuka, Masanori, Shirai, Tomoyuki
Published in Journal of Toxicologic Pathology (2011)
Published in Journal of Toxicologic Pathology (2011)
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P-01 Mode of action of ethyl tertiary-butyl ether tumorigenicity in the rat liver: Evidence for oxidative stress induction via activation of CAR, PXR and PPARs
Anna KAKEHASHI, Akihiro HAGIWARA, Norio IMAI, Min WEI, Kasuke NAGANO, Shoji FUKUSHIMA, Hideki WANIBUCHI
Published in Journal of Toxicologic Pathology (2013)
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Published in Journal of Toxicologic Pathology (2013)
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P-101 A 90 day Feeding Toxicity Study of Magnesium Hydrogen Phosphate (MgHPO4.3H2O) in Sprague-Dawley rats
Takamasa NUMANO, Akihiro HAGIWARA, Hironao NAKASHIMA, Seiko TAMANO, Fumio FURUKAWA, Yuhji TAQUAHASHI, Jun KANNO
Published in Journal of Toxicologic Pathology (2012)
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Published in Journal of Toxicologic Pathology (2012)
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Absence of liver tumor promoting effects of annatto extract (norbixin), a natural carotenoid food color, in a medium-term liver carcinogenesis bioassay using male F344 rats
Hagiwara, Akihiro, Imai, Norio, Doi, Yuko, Nabae, Kyoko, Hirota, Takeshi, Yoshino, Hiroko, Kawabe, Mayumi, Tsushima, Yoko, Aoki, Hiromitsu, Yasuhara, Kazuo, Koda, Takatoshi, Nakamura, Mikio, Shirai, Tomoyuki
Published in Cancer letters (10.09.2003)
Published in Cancer letters (10.09.2003)
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Susceptibility of Four F1 Hybrids of Male Rats to the Promoting Effects of Sodium L-ascorbate in Two-Stage Urinary Bladder Carcinogenesis
Mori, Satoru, Murai, Takashi, Wanibuchi, Hideki, Hagiwara, Akihiro, Puatanachokchai, Rawiwan, Fukushima, Shoji
Published in Journal of Toxicologic Pathology (2006)
Published in Journal of Toxicologic Pathology (2006)
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Inhibitory effect of chlorophyllin on PhIP-induced mammary carcinogenesis in female F344 rats
Hasegawa, R, Hirose, M, Kato, T, Hagiwara, A, Boonyaphiphat, P, Nagao, M, Ito, N, Shirai, T
Published in Carcinogenesis (New York) (01.09.1995)
Published in Carcinogenesis (New York) (01.09.1995)
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