GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality
McCrory, Cathal, Fiorito, Giovanni, Hernandez, Belinda, Polidoro, Silvia, O'Halloran, Aisling M, Hever, Ann, Ni Cheallaigh, Cliona, Lu, Ake T, Horvath, Steve, Vineis, Paolo, Kenny, Rose Anne
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.05.2021)
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01.05.2021)
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DNA methylation GrimAge strongly predicts lifespan and healthspan
Lu, Ake T, Quach, Austin, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Raj, Kenneth, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Assimes, Themistocles L, Ferrucci, Luigi, Horvath, Steve
Published in Aging (Albany, NY.) (21.01.2019)
Published in Aging (Albany, NY.) (21.01.2019)
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An epigenetic clock analysis of race/ethnicity, sex, and coronary heart disease
Horvath, Steve, Gurven, Michael, Levine, Morgan E, Trumble, Benjamin C, Kaplan, Hillard, Allayee, Hooman, Ritz, Beate R, Chen, Brian, Lu, Ake T, Rickabaugh, Tammy M, Jamieson, Beth D, Sun, Dianjianyi, Li, Shengxu, Chen, Wei, Quintana-Murci, Lluis, Fagny, Maud, Kobor, Michael S, Tsao, Philip S, Reiner, Alexander P, Edlefsen, Kerstin L, Absher, Devin, Assimes, Themistocles L
Published in Genome Biology (11.08.2016)
Published in Genome Biology (11.08.2016)
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A mammalian methylation array for profiling methylation levels at conserved sequences
Arneson, Adriana, Haghani, Amin, Thompson, Michael J., Pellegrini, Matteo, Kwon, Soo Bin, Vu, Ha, Maciejewski, Emily, Yao, Mingjia, Li, Caesar Z., Lu, Ake T., Morselli, Marco, Rubbi, Liudmilla, Barnes, Bret, Hansen, Kasper D., Zhou, Wanding, Breeze, Charles E., Ernst, Jason, Horvath, Steve
Published in Nature communications (10.02.2022)
Published in Nature communications (10.02.2022)
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Fundamental equations linking methylation dynamics to maximum lifespan in mammals
Horvath, Steve, Zhang, Joshua, Haghani, Amin, Lu, Ake T., Fei, Zhe
Published in Nature communications (16.09.2024)
Published in Nature communications (16.09.2024)
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Epigenetic clock for skin and blood cells applied to Hutchinson Gilford Progeria Syndrome and ex vivo studies
Horvath, Steve, Oshima, Junko, Martin, George M, Lu, Ake T, Quach, Austin, Cohen, Howard, Felton, Sarah, Matsuyama, Mieko, Lowe, Donna, Kabacik, Sylwia, Wilson, James G, Reiner, Alex P, Maierhofer, Anna, Flunkert, Julia, Aviv, Abraham, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Stewart, James D, Whitsel, Eric A, Ferrucci, Luigi, Matsuyama, Shigemi, Raj, Kenneth
Published in Aging (Albany, NY.) (26.07.2018)
Published in Aging (Albany, NY.) (26.07.2018)
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Journal Article
Menopause accelerates biological aging
Levine, Morgan E., Lu, Ake T., Chen, Brian H., Hernandez, Dena G., Singleton, Andrew B., Ferrucci, Luigi, Bandinelli, Stefania, Salfati, Elias, Manson, JoAnn E., Quach, Austin, Kusters, Cynthia D. J., Kuh, Diana, Wong, Andrew, Teschendorff, Andrew E., Widschwendter, Martin, Ritz, Beate R., Absher, Devin, Assimes, Themistocles L., Horvath, Steve
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (16.08.2016)
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Epigenetic clock analysis of diet, exercise, education, and lifestyle factors
Quach, Austin, Levine, Morgan E, Tanaka, Toshiko, Lu, Ake T, Chen, Brian H, Ferrucci, Luigi, Ritz, Beate, Bandinelli, Stefania, Neuhouser, Marian L, Beasley, Jeannette M, Snetselaar, Linda, Wallace, Robert B, Tsao, Philip S, Absher, Devin, Assimes, Themistocles L, Stewart, James D, Li, Yun, Hou, Lifang, Baccarelli, Andrea A, Whitsel, Eric A, Horvath, Steve
Published in Aging (Albany, NY.) (14.02.2017)
Published in Aging (Albany, NY.) (14.02.2017)
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Journal Article
An epigenetic biomarker of aging for lifespan and healthspan
Levine, Morgan E, Lu, Ake T, Quach, Austin, Chen, Brian H, Assimes, Themistocles L, Bandinelli, Stefania, Hou, Lifang, Baccarelli, Andrea A, Stewart, James D, Li, Yun, Whitsel, Eric A, Wilson, James G, Reiner, Alex P, Aviv, Abraham, Lohman, Kurt, Liu, Yongmei, Ferrucci, Luigi, Horvath, Steve
Published in Aging (Albany, NY.) (18.04.2018)
Published in Aging (Albany, NY.) (18.04.2018)
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Journal Article
Refining epigenetic prediction of chronological and biological age
Bernabeu, Elena, McCartney, Daniel L, Gadd, Danni A, Hillary, Robert F, Lu, Ake T, Murphy, Lee, Wrobel, Nicola, Campbell, Archie, Harris, Sarah E, Liewald, David, Hayward, Caroline, Sudlow, Cathie, Cox, Simon R, Evans, Kathryn L, Horvath, Steve, McIntosh, Andrew M, Robinson, Matthew R, Vallejos, Catalina A, Marioni, Riccardo E
Published in Genome medicine (28.02.2023)
Published in Genome medicine (28.02.2023)
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A meta-analysis of genome-wide association studies of epigenetic age acceleration
Gibson, Jude, Russ, Tom C, Clarke, Toni-Kim, Howard, David M, Hillary, Robert F, Evans, Kathryn L, Walker, Rosie M, Bermingham, Mairead L, Morris, Stewart W, Campbell, Archie, Hayward, Caroline, Murray, Alison D, Porteous, David J, Horvath, Steve, Lu, Ake T, McIntosh, Andrew M, Whalley, Heather C, Marioni, Riccardo E
Published in PLoS genetics (18.11.2019)
Published in PLoS genetics (18.11.2019)
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DNA methylation study of Huntington’s disease and motor progression in patients and in animal models
Lu, Ake T., Narayan, Pritika, Grant, Matthew J., Langfelder, Peter, Wang, Nan, Kwak, Seung, Wilkinson, Hilary, Chen, Richard Z., Chen, Jian, Simon Bawden, C., Rudiger, Skye R., Ciosi, Marc, Chatzi, Afroditi, Maxwell, Alastair, Hore, Timothy A., Aaronson, Jeff, Rosinski, Jim, Preiss, Alicia, Vogt, Thomas F., Coppola, Giovanni, Monckton, Darren, Snell, Russell G., William Yang, X., Horvath, Steve
Published in Nature communications (10.09.2020)
Published in Nature communications (10.09.2020)
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Journal Article
DNA methylation-based estimator of telomere length
Lu, Ake T, Seeboth, Anne, Tsai, Pei-Chien, Sun, Dianjianyi, Quach, Austin, Reiner, Alex P, Kooperberg, Charles, Ferrucci, Luigi, Hou, Lifang, Baccarelli, Andrea A, Li, Yun, Harris, Sarah E, Corley, Janie, Taylor, Adele, Deary, Ian J, Stewart, James D, Whitsel, Eric A, Assimes, Themistocles L, Chen, Wei, Li, Shengxu, Mangino, Massimo, Bell, Jordana T, Wilson, James G, Aviv, Abraham, Marioni, Riccardo E, Raj, Kenneth, Horvath, Steve
Published in Aging (Albany, NY.) (18.08.2019)
Published in Aging (Albany, NY.) (18.08.2019)
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Journal Article
Epigenetic Age Acceleration Reflects Long-Term Cardiovascular Health
Joyce, Brian T, Gao, Tao, Zheng, Yinan, Ma, Jiantao, Hwang, Shih-Jen, Liu, Lei, Nannini, Drew, Horvath, Steve, Lu, Ake T, Bai Allen, Norrina, Jacobs, Jr, David R, Gross, Myron, Krefman, Amy, Ning, Hongyan, Liu, Kiang, Lewis, Cora E, Schreiner, Pamela J, Sidney, Stephen, Shikany, James M, Levy, Daniel, Greenland, Philip, Hou, Lifang, Lloyd-Jones, Donald
Published in Circulation research (01.10.2021)
Published in Circulation research (01.10.2021)
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Journal Article
Biological age is increased by stress and restored upon recovery
Poganik, Jesse R., Zhang, Bohan, Baht, Gurpreet S., Tyshkovskiy, Alexander, Deik, Amy, Kerepesi, Csaba, Yim, Sun Hee, Lu, Ake T., Haghani, Amin, Gong, Tong, Hedman, Anna M., Andolf, Ellika, Pershagen, Göran, Almqvist, Catarina, Clish, Clary B., Horvath, Steve, White, James P., Gladyshev, Vadim N.
Published in Cell metabolism (02.05.2023)
Published in Cell metabolism (02.05.2023)
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Journal Article
Genetic loci and metabolic states associated with murine epigenetic aging
Mozhui, Khyobeni, Lu, Ake T, Li, Caesar Z, Haghani, Amin, Sandoval-Sierra, Jose Vladimir, Wu, Yibo, Williams, Robert W, Horvath, Steve
Published in eLife (07.04.2022)
Published in eLife (07.04.2022)
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