The chaperone proteins HSP70, HSP40/DnaJ and GRP78/BiP suppress misfolding and formation of β-sheet-containing aggregates by human amylin: a potential role for defective chaperone biology in Type 2 diabetes
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Published in Biochemical journal (15.11.2010)
Published in Biochemical journal (15.11.2010)
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Tetracycline Treatment Retards the Onset and Slows the Progression of Diabetes in Human Amylin/Islet Amyloid Polypeptide Transgenic Mice
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Published in Diabetes (New York, N.Y.) (01.01.2010)
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Novel Peptide Antagonists of Adrenomedullin and Calcitonin Gene-Related Peptide Receptors: Identification, Pharmacological Characterization, and Interactions with Position 74 in Receptor Activity-Modifying Protein 1/3
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Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2009)
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Thiol reducing compounds prevent human amylin‐evoked cytotoxicity
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Published in The FEBS journal (01.10.2005)
Published in The FEBS journal (01.10.2005)
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Quantitative data describing the impact of the flavonol rutin on in-vivo blood-glucose and fluid-intake profiles, and survival of human-amylin transgenic mice
Aitken, Jacqueline F., Loomes, Kerry M., Riba-Garcia, Isabel, Unwin, Richard D., Prijic, Gordana, Phillips, Ashley S., Phillips, Anthony R.J., Wu, Donghai, Poppitt, Sally D., Ding, Ke, Barran, Perdita E., Dowsey, Andrew W., Cooper, Garth J.S.
Published in Data in brief (01.02.2017)
Published in Data in brief (01.02.2017)
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Rutin suppresses human-amylin/hIAPP misfolding and oligomer formation in-vitro, and ameliorates diabetes and its impacts in human-amylin/hIAPP transgenic mice
Aitken, Jacqueline F., Loomes, Kerry M., Riba-Garcia, Isabel, Unwin, Richard D., Prijic, Gordana, Phillips, Ashley S., Phillips, Anthony R.J., Wu, Donghai, Poppitt, Sally D., Ding, Ke, Barran, Perdita E., Dowsey, Andrew W., Cooper, Garth J.S.
Published in Biochemical and biophysical research communications (22.01.2017)
Published in Biochemical and biophysical research communications (22.01.2017)
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Vesiculin derived from IGF-II drives increased islet cell mass in a mouse model of pre-diabetes
Lee, Kate L., Aitken, Jacqueline F., Li, Xun, Montgomery, Kirsten, Hsu, Huai-L., Williams, Geoffrey M., Brimble, Margaret A., Cooper, Garth J.S.
Published in Islets (01.01.2022)
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Monodisperse 130 kDa and 260 kDa Recombinant Human Hemoglobin Polymers as Scaffolds for Protein Engineering of Hemoglobin-Based Oxygen Carriers
Marquardt, David A, Doyle, Michael P, Davidson, Jeffrey S, Epp, Janet K, Aitken, Jacqueline F, Lemon, Douglas D, Anthony-Cahill, Spencer J
Published in Journal of functional biomaterials (13.01.2012)
Published in Journal of functional biomaterials (13.01.2012)
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Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid
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Published in Biochemical journal (15.09.2003)
Published in Biochemical journal (15.09.2003)
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Mechanism of NO-Induced Oxidation of Myoglobin and Hemoglobin
Eich, Raymund F, Li, Tiansheng, Lemon, Douglas D, Doherty, Daniel H, Curry, Shawn R, Aitken, Jacqueline F, Mathews, Antony J, Johnson, Kenneth A, Smith, Robert D, Phillips, George N, Olson, John S
Published in Biochemistry (Easton) (04.06.1996)
Published in Biochemistry (Easton) (04.06.1996)
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COMPOUNDS FOR TREATING DIABETES AND/OR RELATED CONDITIONS
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Year of Publication 03.08.2022
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COMPOUNDS FOR TREATING DIABETES AND/OR RELATED CONDITIONS
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Year of Publication 10.02.2022
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COMPOUNDS FOR TREATING DIABETES AND/OR RELATED CONDITIONS
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Year of Publication 25.08.2021
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COMPOUNDS FOR TREATING DIABETES AND/OR RELATED CONDITIONS
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Year of Publication 23.04.2020
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The gene encoding the phosphatidylinositol transfer protein is essential for cell growth
Aitken, J F, van Heusden, G P, Temkin, M, Dowhan, W
Published in The Journal of biological chemistry (15.03.1990)
Published in The Journal of biological chemistry (15.03.1990)
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Proteins with mutations to decrease N-terminal methylation
APOSTOL; IZYDOR Z, AITKEN; JACQUELINE F, LIPPINCOTT; JULIE A, LEVINE; JOSEPH D
Year of Publication 31.10.2000
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Year of Publication 31.10.2000
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