Association Between Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons
Donohue, Michael C, Sperling, Reisa A, Petersen, Ronald, Sun, Chung-Kai, Weiner, Michael W, Aisen, Paul S
Published in JAMA : the journal of the American Medical Association (13.06.2017)
Published in JAMA : the journal of the American Medical Association (13.06.2017)
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Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease
Egan, Michael F, Kost, James, Tariot, Pierre N, Aisen, Paul S, Cummings, Jeffrey L, Vellas, Bruno, Sur, Cyrille, Mukai, Yuki, Voss, Tiffini, Furtek, Christine, Mahoney, Erin, Harper Mozley, Lyn, Vandenberghe, Rik, Mo, Yi, Michelson, David
Published in The New England journal of medicine (03.05.2018)
Published in The New England journal of medicine (03.05.2018)
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Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
Jack, Clifford R, Prof Dr, Knopman, David S, Prof, Jagust, William J, Prof, Petersen, Ronald C, Prof, Weiner, Michael W, Prof, Aisen, Paul S, Prof, Shaw, Leslie M, Prof, Vemuri, Prashanthi, PhD, Wiste, Heather J, Weigand, Stephen D, Lesnick, Timothy G, Pankratz, Vernon S, PhD, Donohue, Michael C, PhD, Trojanowski, John Q, Prof
Published in Lancet neurology (01.02.2013)
Published in Lancet neurology (01.02.2013)
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Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
Doody, Rachelle S, Thomas, Ronald G, Farlow, Martin, Iwatsubo, Takeshi, Vellas, Bruno, Joffe, Steven, Kieburtz, Karl, Raman, Rema, Sun, Xiaoying, Aisen, Paul S, Siemers, Eric, Liu-Seifert, Hong, Mohs, Richard
Published in The New England journal of medicine (23.01.2014)
Published in The New England journal of medicine (23.01.2014)
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Trial of Solanezumab in Preclinical Alzheimer’s Disease
Sperling, Reisa A., Donohue, Michael C., Raman, Rema, Rafii, Michael S., Johnson, Keith, Masters, Colin L., van Dyck, Christopher H., Iwatsubo, Takeshi, Marshall, Gad A., Yaari, Roy, Mancini, Michele, Holdridge, Karen C., Case, Michael, Sims, John R., Aisen, Paul S.
Published in The New England journal of medicine (21.09.2023)
Published in The New England journal of medicine (21.09.2023)
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Randomized Trial of Verubecestat for Prodromal Alzheimer’s Disease
Egan, Michael F, Kost, James, Voss, Tiffini, Mukai, Yuki, Aisen, Paul S, Cummings, Jeffrey L, Tariot, Pierre N, Vellas, Bruno, van Dyck, Christopher H, Boada, Merce, Zhang, Ying, Li, Wen, Furtek, Christine, Mahoney, Erin, Harper Mozley, Lyn, Mo, Yi, Sur, Cyrille, Michelson, David
Published in The New England journal of medicine (11.04.2019)
Published in The New England journal of medicine (11.04.2019)
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A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease
Doody, Rachelle S, Raman, Rema, Farlow, Martin, Iwatsubo, Takeshi, Vellas, Bruno, Joffe, Steven, Kieburtz, Karl, He, Feng, Sun, Xiaoying, Thomas, Ronald G, Aisen, Paul S, Siemers, Eric, Sethuraman, Gopalan, Mohs, Richard
Published in The New England journal of medicine (25.07.2013)
Published in The New England journal of medicine (25.07.2013)
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Testing the right target and right drug at the right stage
Sperling, Reisa A, Jack, Jr, Clifford R, Aisen, Paul S
Published in Science translational medicine (30.11.2011)
Published in Science translational medicine (30.11.2011)
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Journal Article
Amyloid deposition, hypometabolism, and longitudinal cognitive decline
Landau, Susan M., Mintun, Mark A., Joshi, Abhinay D., Koeppe, Robert A., Petersen, Ronald C., Aisen, Paul S., Weiner, Michael W., Jagust, William J.
Published in Annals of neurology (01.10.2012)
Published in Annals of neurology (01.10.2012)
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The AHEAD 3‐45 Study: Design of a prevention trial for Alzheimer's disease
Rafii, Michael S., Sperling, Reisa A., Donohue, Michael C., Zhou, Jin, Roberts, Claire, Irizarry, Michael C., Dhadda, Shobha, Sethuraman, Gopalan, Kramer, Lynn D, Swanson, Chad J, Li, David, Krause, Stephen, Rissman, Robert A., Walter, Sarah, Raman, Rema, Johnson, Keith A., Aisen, Paul S.
Published in Alzheimer's & dementia (01.04.2023)
Published in Alzheimer's & dementia (01.04.2023)
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A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease
Turner, R Scott, Thomas, Ronald G, Craft, Suzanne, van Dyck, Christopher H, Mintzer, Jacobo, Reynolds, Brigid A, Brewer, James B, Rissman, Robert A, Raman, Rema, Aisen, Paul S
Published in Neurology (20.10.2015)
Published in Neurology (20.10.2015)
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Drug development in Alzheimer's disease: the path to 2025
Cummings, Jeffrey, Aisen, Paul S, DuBois, Bruno, Frölich, Lutz, Jack, Jr, Clifford R, Jones, Roy W, Morris, John C, Raskin, Joel, Dowsett, Sherie A, Scheltens, Philip
Published in Alzheimer's research & therapy (20.09.2016)
Published in Alzheimer's research & therapy (20.09.2016)
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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Jack, Clifford R, MD, Knopman, David S, MD, Jagust, William J, MD, Shaw, Leslie M, PhD, Aisen, Paul S, MD, Weiner, Michael W, MD, Petersen, Ronald C, MD, Trojanowski, John Q, PhD
Published in Lancet neurology (2010)
Published in Lancet neurology (2010)
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Journal Article
On the path to 2025: understanding the Alzheimer's disease continuum
Aisen, Paul S, Cummings, Jeffrey, Jack, Jr, Clifford R, Morris, John C, Sperling, Reisa, Frölich, Lutz, Jones, Roy W, Dowsett, Sherie A, Matthews, Brandy R, Raskin, Joel, Scheltens, Philip, Dubois, Bruno
Published in Alzheimer's research & therapy (09.08.2017)
Published in Alzheimer's research & therapy (09.08.2017)
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The Alzheimer's Disease Neuroimaging Initiative 3: Continued innovation for clinical trial improvement
Weiner, Michael W, Veitch, Dallas P, Aisen, Paul S, Beckett, Laurel A, Cairns, Nigel J, Green, Robert C, Harvey, Danielle, Jack, Clifford R, Jagust, William, Morris, John C, Petersen, Ronald C, Salazar, Jennifer, Saykin, Andrew J, Shaw, Leslie M, Toga, Arthur W, Trojanowski, John Q
Published in Alzheimer's & dementia (01.05.2017)
Published in Alzheimer's & dementia (01.05.2017)
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Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
Shaw, Leslie M., Vanderstichele, Hugo, Knapik-Czajka, Malgorzata, Clark, Christopher M., Aisen, Paul S., Petersen, Ronald C., Blennow, Kaj, Soares, Holly, Simon, Adam, Lewczuk, Piotr, Dean, Robert, Siemers, Eric, Potter, William, Lee, Virginia M.-Y., Trojanowski, John Q.
Published in Annals of neurology (01.04.2009)
Published in Annals of neurology (01.04.2009)
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Journal Article
Recent publications from the Alzheimer's Disease Neuroimaging Initiative: Reviewing progress toward improved AD clinical trials
Weiner, Michael W, Veitch, Dallas P, Aisen, Paul S, Beckett, Laurel A, Cairns, Nigel J, Green, Robert C, Harvey, Danielle, Jack, Clifford R, Jagust, William, Morris, John C, Petersen, Ronald C, Saykin, Andrew J, Shaw, Leslie M, Toga, Arthur W, Trojanowski, John Q
Published in Alzheimer's & dementia (01.04.2017)
Published in Alzheimer's & dementia (01.04.2017)
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Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
Sperling, Reisa A, Aisen, Paul S, Beckett, Laurel A, Bennett, David A, Craft, Suzanne, Fagan, Anne M, Iwatsubo, Takeshi, Jack, Clifford R, Kaye, Jeffrey, Montine, Thomas J, Park, Denise C, Reiman, Eric M, Rowe, Christopher C, Siemers, Eric, Stern, Yaakov, Yaffe, Kristine, Carrillo, Maria C, Thies, Bill, Morrison-Bogorad, Marcelle, Wagster, Molly V, Phelps, Creighton H
Published in Alzheimer's & dementia (01.05.2011)
Published in Alzheimer's & dementia (01.05.2011)
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Conference Proceeding