NAD + metabolism governs the proinflammatory senescence-associated secretome
Nacarelli, Timothy, Lau, Lena, Fukumoto, Takeshi, Zundell, Joseph, Fatkhutdinov, Nail, Wu, Shuai, Aird, Katherine M, Iwasaki, Osamu, Kossenkov, Andrew V, Schultz, David, Noma, Ken-Ichi, Baur, Joseph A, Schug, Zachary, Tang, Hsin-Yao, Speicher, David W, David, Gregory, Zhang, Rugang
Published in Nature cell biology (01.03.2019)
Published in Nature cell biology (01.03.2019)
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Synthetic lethality by targeting EZH2 methyltransferase activity in ARID1A-mutated cancers
Bitler, Benjamin G, Aird, Katherine M, Garipov, Azat, Li, Hua, Amatangelo, Michael, Kossenkov, Andrew V, Schultz, David C, Liu, Qin, Shih, Ie-Ming, Conejo-Garcia, Jose R, Speicher, David W, Zhang, Rugang
Published in Nature medicine (01.03.2015)
Published in Nature medicine (01.03.2015)
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Suppression of Nucleotide Metabolism Underlies the Establishment and Maintenance of Oncogene-Induced Senescence
Aird, Katherine M., Zhang, Gao, Li, Hua, Tu, Zhigang, Bitler, Benjamin G., Garipov, Azat, Wu, Hong, Wei, Zhi, Wagner, Stephan N., Herlyn, Meenhard, Zhang, Rugang
Published in Cell reports (Cambridge) (25.04.2013)
Published in Cell reports (Cambridge) (25.04.2013)
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ARID1A-mutated ovarian cancers depend on HDAC6 activity
Bitler, Benjamin G, Wu, Shuai, Park, Pyoung Hwa, Hai, Yang, Aird, Katherine M, Wang, Yemin, Zhai, Yali, Kossenkov, Andrew V, Vara-Ailor, Ana, Rauscher, III, Frank J, Zou, Weiping, Speicher, David W, Huntsman, David G, Conejo-Garcia, Jose R, Cho, Kathleen R, Christianson, David W, Zhang, Rugang
Published in Nature cell biology (01.08.2017)
Published in Nature cell biology (01.08.2017)
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HMGB2 orchestrates the chromatin landscape of senescence-associated secretory phenotype gene loci
Aird, Katherine M, Iwasaki, Osamu, Kossenkov, Andrew V, Tanizawa, Hideki, Fatkhutdinov, Nail, Bitler, Benjamin G, Le, Linh, Alicea, Gretchen, Yang, Ting-Lin, Johnson, F Brad, Noma, Ken-Ichi, Zhang, Rugang
Published in The Journal of cell biology (07.11.2016)
Published in The Journal of cell biology (07.11.2016)
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Suppression of p16 alleviates the senescence-associated secretory phenotype
Buj, Raquel, Leon, Kelly E, Anguelov, Marlyn A, Aird, Katherine M
Published in Aging (Albany, NY.) (06.02.2021)
Published in Aging (Albany, NY.) (06.02.2021)
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PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion
Caino, M. Cecilia, Jagadish C. Ghosh, Young Chan Chae, Valentina Vaira, Dayana B. Rivadeneira, Alice Faversani, Paolo Rampini, Andrew V. Kossenkov, Katherine M. Aird, Rugang Zhang, Marie R. Webster, Ashani T. Weeraratna, Silvano Bosari, Lucia R. Languino, Dario C. Altieri
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.07.2015)
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Topoisomerase 1 cleavage complex enables pattern recognition and inflammation during senescence
Zhao, Bo, Liu, Pingyu, Fukumoto, Takeshi, Nacarelli, Timothy, Fatkhutdinov, Nail, Wu, Shuai, Lin, Jianhuang, Aird, Katherine M, Tang, Hsin-Yao, Liu, Qin, Speicher, David W, Zhang, Rugang
Published in Nature communications (19.02.2020)
Published in Nature communications (19.02.2020)
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sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
Kaur, Amanpreet, Webster, Marie R, Marchbank, Katie, Behera, Reeti, Ndoye, Abibatou, Kugel, 3rd, Curtis H, Dang, Vanessa M, Appleton, Jessica, O'Connell, Michael P, Cheng, Phil, Valiga, Alexander A, Morissette, Rachel, McDonnell, Nazli B, Ferrucci, Luigi, Kossenkov, Andrew V, Meeth, Katrina, Tang, Hsin-Yao, Yin, Xiangfan, Wood, 3rd, William H, Lehrmann, Elin, Becker, Kevin G, Flaherty, Keith T, Frederick, Dennie T, Wargo, Jennifer A, Cooper, Zachary A, Tetzlaff, Michael T, Hudgens, Courtney, Aird, Katherine M, Zhang, Rugang, Xu, Xiaowei, Liu, Qin, Bartlett, Edmund, Karakousis, Giorgos, Eroglu, Zeynep, Lo, Roger S, Chan, Matthew, Menzies, Alexander M, Long, Georgina V, Johnson, Douglas B, Sosman, Jeffrey, Schilling, Bastian, Schadendorf, Dirk, Speicher, David W, Bosenberg, Marcus, Ribas, Antoni, Weeraratna, Ashani T
Published in Nature (London) (14.04.2016)
Published in Nature (London) (14.04.2016)
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ATM inhibition drives metabolic adaptation via induction of macropinocytosis
Huang, Zhentai, Chen, Chi-Wei, Buj, Raquel, Tangudu, Naveen Kumar, Fang, Richard S, Leon, Kelly E, Dahl, Erika S, Varner, Erika L, von Krusenstiern, Eliana, Cole, Aidan R, Snyder, Nathaniel W, Aird, Katherine M
Published in The Journal of cell biology (02.01.2023)
Published in The Journal of cell biology (02.01.2023)
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DOT1L modulates the senescence-associated secretory phenotype through epigenetic regulation of IL1A
Leon, Kelly E, Buj, Raquel, Lesko, Elizabeth, Dahl, Erika S, Chen, Chi-Wei, Tangudu, Naveen Kumar, Imamura-Kawasawa, Yuka, Kossenkov, Andrew V, Hobbs, Ryan P, Aird, Katherine M
Published in The Journal of cell biology (02.08.2021)
Published in The Journal of cell biology (02.08.2021)
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ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence
Aird, Katherine M., Worth, Andrew J., Snyder, Nathaniel W., Lee, Joyce V., Sivanand, Sharanya, Liu, Qin, Blair, Ian A., Wellen, Kathryn E., Zhang, Rugang
Published in Cell reports (Cambridge) (12.05.2015)
Published in Cell reports (Cambridge) (12.05.2015)
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SPOP E3 Ubiquitin Ligase Adaptor Promotes Cellular Senescence by Degrading the SENP7 deSUMOylase
Zhu, Hengrui, Ren, Shancheng, Bitler, Benjamin G., Aird, Katherine M., Tu, Zhigang, Skordalakes, Emmanuel, Zhu, Yasheng, Yan, Jun, Sun, Yinghao, Zhang, Rugang
Published in Cell reports (Cambridge) (10.11.2015)
Published in Cell reports (Cambridge) (10.11.2015)
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Oncogenic Ras Regulates BRIP1 Expression to Induce Dissociation of BRCA1 from Chromatin, Inhibit DNA Repair, and Promote Senescence
Tu, Zhigang, Aird, Katherine M., Bitler, Benjamin G., Nicodemus, Jasmine P., Beeharry, Neil, Xia, Bing, Yen, Tim J., Zhang, Rugang
Published in Developmental cell (13.12.2011)
Published in Developmental cell (13.12.2011)
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