Application of toxicogenomics to study mechanisms of genotoxicity and carcinogenicity
Ellinger-Ziegelbauer, Heidrun, Aubrecht, Jiri, Kleinjans, Jos C., Ahr, Hans-Juergen
Published in Toxicology letters (10.04.2009)
Published in Toxicology letters (10.04.2009)
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Journal Article
Prediction of a carcinogenic potential of rat hepatocarcinogens using toxicogenomics analysis of short-term in vivo studies
Ellinger-Ziegelbauer, Heidrun, Gmuender, Hans, Bandenburg, Arnd, Ahr, Hans Juergen
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.01.2008)
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (01.01.2008)
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Journal Article
Comparison of the expression profiles induced by genotoxic and nongenotoxic carcinogens in rat liver
Ellinger-Ziegelbauer, Heidrun, Stuart, Barry, Wahle, Brad, Bomann, Werner, Ahr, Hans Juergen
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (04.08.2005)
Published in Mutation Research-Fundamental and Molecular Mechanisms of Mutagenesis (04.08.2005)
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Journal Article
Carcinogen-specific gene expression profiles in short-term treated eker and wild-type rats indicative of pathways involved in renal tumorigenesis
STEMMER, Kerstin, ELLINGER -ZIEGELBAUER, Heidrun, AHR, Hans-Juergen, DIETRICH, Daniel R
Published in Cancer research (Chicago, Ill.) (01.05.2007)
Published in Cancer research (Chicago, Ill.) (01.05.2007)
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Journal Article
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver
Doktorova, Tatyana Y., Ellinger-Ziegelbauer, Heidrun, Vinken, Mathieu, Vanhaecke, Tamara, van Delft, Joost, Kleinjans, Jos, Ahr, Hans-Juergen, Rogiers, Vera
Published in Archives of toxicology (01.09.2012)
Published in Archives of toxicology (01.09.2012)
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Journal Article
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data
Doktorova, Tatyana Y., Ellinger-Ziegelbauer, Heidrun, Vinken, Mathieu, Vanhaecke, Tamara, van Delft, Joost, Kleinjans, Jos, Ahr, Hans-Juergen, Rogiers, Vera
Published in Archives of toxicology (01.11.2012)
Published in Archives of toxicology (01.11.2012)
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Journal Article
Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion
Jennings, Paul, Aydin, Sonia, Bennett, Jason, McBride, Rachael, Weiland, Christina, Tuite, Niamh, Gruber, Leonhard N., Perco, Paul, Gaora, Peadar Ó, Ellinger-Ziegelbauer, Heidrun, Ahr, Hans-Juergen, Kooten, Cees Van, Daha, Mohamed R., Prieto, Pilar, Ryan, Michael P., Pfaller, Walter, McMorrow, Tara
Published in Toxicology in vitro (01.04.2009)
Published in Toxicology in vitro (01.04.2009)
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Journal Article
Embryonic turkey liver: activities of biotransformation enzymes and activation of DNA-reactive carcinogens
PERRONE, Carmen E, AHR, Hans-Juergen, JIAN DONG DUAN, JEFFREY, Alan M, SCHMIDT, Ulrich, WILLIAMS, Gary M, ENZMANN, Harald H
Published in Archives of toxicology (01.10.2004)
Published in Archives of toxicology (01.10.2004)
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Journal Article
A review of the implementation of the embryonic stem cell test (EST). The report and recommendations of an ECVAM/ReProTect Workshop
Marx-Stoelting, Philip, Adriaens, Els, Ahr, Hans-Jürgen, Bremer, Susanne, Garthoff, Bernward, Gelbke, Heinz-Peter, Piersma, Aldert, Pellizzer, Cristian, Reuter, Ulrike, Rogiers, Vera, Schenk, Barbara, Schwengberg, Silke, Seiler, Andrea, Spielmann, Horst, Steemans, Margino, Stedman, Donald B, Vanparys, Philippe, Vericat, Joan Albert, Verwei, Miriam, van der Water, Femke, Weimer, Marc, Schwarz, Michael
Published in Alternatives to laboratory animals (01.07.2009)
Published in Alternatives to laboratory animals (01.07.2009)
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Journal Article
The SEURAT-1 approach towards animal free human safety assessment
Gocht, Tilman, Berggren, Elisabet, Ahr, Hans Jürgen, Cotgreave, Ian, Cronin, Mark T D, Daston, George, Hardy, Barry, Heinzle, Elmar, Hescheler, Jürgen, Knight, Derek J, Mahony, Catherine, Peschanski, Marc, Schwarz, Michael, Thomas, Russell S, Verfaillie, Catherine, White, Andrew, Whelan, Maurice
Published in ALTEX, alternatives to animal experimentation (2015)
Published in ALTEX, alternatives to animal experimentation (2015)
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Journal Article
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes
Schug, Markus, Stöber, Regina, Heise, Tanja, Mielke, Hans, Gundert-Remy, Ursula, Godoy, Patricio, Reif, Raymond, Blaszkewicz, Meinolf, Ellinger-Ziegelbauer, Heidrun, Ahr, Hans-Jürgen, Selinski, Silvia, Günther, Georgia, Marchan, Rosemarie, Sachinidis, Agapios, Nüssler, Andreas, Oberemm, Axel, Hengstler, Jan G.
Published in Archives of toxicology (01.02.2013)
Published in Archives of toxicology (01.02.2013)
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Journal Article
Induction of chondro-, osteo- and adipogenesis in embryonic stem cells by bone morphogenetic protein-2: effect of cofactors on differentiating lineages
zur Nieden, Nicole I, Kempka, Grazyna, Rancourt, Derrick E, Ahr, Hans-Jürgen
Published in BMC developmental biology (26.01.2005)
Published in BMC developmental biology (26.01.2005)
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Journal Article
Assessment of a robust model protocol with accelerated throughput for a human recombinant full length estrogen receptor-α binding assay: Protocol optimization and intralaboratory assay performance as initial steps towards validation
Freyberger, Alexius, Wilson, Vickie, Weimer, Marc, Tan, Shirlee, Tran, Hoai-Son, Ahr, Hans-Jürgen
Published in Reproductive toxicology (Elmsford, N.Y.) (01.08.2010)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.08.2010)
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Journal Article
Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM-ICCVAM/NICEATM Considerations for Regulatory Use
Corvi, Raffaella, Ahr, Hans-Jürgen, Albertini, Silvio, Blakey, David H., Clerici, Libero, Coecke, Sandra, Douglas, George R., Gribaldo, Laura, Groten, John P., Haase, Bernd, Hamernik, Karen, Hartung, Thomas, Inoue, Tohru, Indans, Ian, Maurici, Daniela, Orphanides, George, Rembges, Diana, Sansone, Susanna-Assunta, Snape, Jason R., Toda, Eisaku, Tong, Weida, van Delft, Joost H., Weis, Brenda, Schechtman, Leonard M.
Published in Environmental health perspectives (01.03.2006)
Published in Environmental health perspectives (01.03.2006)
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Journal Article
The carcinoGENOMICS project: Critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays
Vinken, Mathieu, Doktorova, Tatyana, Ellinger-Ziegelbauer, Heidrun, Ahr, Hans-Jürgen, Lock, Edward, Carmichael, Paul, Roggen, Erwin, van Delft, Joost, Kleinjans, Jos, Castell, José, Bort, Roque, Donato, Teresa, Ryan, Michael, Corvi, Raffaella, Keun, Hector, Ebbels, Timothy, Athersuch, Toby, Sansone, Susanna-Assunta, Rocca-Serra, Philippe, Stierum, Rob, Jennings, Paul, Pfaller, Walter, Gmuender, Hans, Vanhaecke, Tamara, Rogiers, Vera
Published in Mutation research (01.09.2008)
Published in Mutation research (01.09.2008)
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Journal Article
Assessment of a robust model protocol with accelerated throughput for a human recombinant full length estrogen receptor-a binding assay: Protocol optimization and intralaboratory assay performance as initial steps towards validation
Freyberger, Alexius, Wilson, Vickie, Weimer, Marc, Tan, Shirlee, Tran, Hoai-Son, Ahr, Hans-Juergen
Published in Reproductive toxicology (Elmsford, N.Y.) (01.08.2010)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.08.2010)
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Journal Article