Dysregulation of mitochondrial dynamics proteins are a targetable feature of human tumors
Anderson, Gray R., Wardell, Suzanne E., Cakir, Merve, Yip, Catherine, Ahn, Yeong-ran, Ali, Moiez, Yllanes, Alexander P., Chao, Christina A., McDonnell, Donald P., Wood, Kris C.
Published in Nature communications (26.04.2018)
Published in Nature communications (26.04.2018)
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Prexasertib, a cell cycle checkpoint kinases 1 and 2 inhibitor, increases in vitro toxicity of PARP inhibition by preventing Rad51 foci formation in BRCA wild type high-grade serous ovarian cancer
Brill, Ethan, Yokoyama, Takuhei, Nair, Jayakumar, Yu, Minshu, Ahn, Yeong-Ran, Lee, Jung-Min
Published in Oncotarget (19.12.2017)
Published in Oncotarget (19.12.2017)
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Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
Lin, Kevin H., Xie, Abigail, Rutter, Justine C., Ahn, Yeong-ran, Lloyd-Cowden, Julia M., Nichols, Amanda G., Soderquist, Ryan S., Koves, Timothy R., Muoio, Deborah M., MacIver, Nancie J., Lamba, Jatinder K., Pardee, Timothy S., McCall, Chad M., Rizzieri, David A., Wood, Kris C.
Published in Cell metabolism (07.05.2019)
Published in Cell metabolism (07.05.2019)
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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer
Lin, Kevin H., Rutter, Justine C., Xie, Abigail, Pardieu, Bryann, Winn, Emily T., Bello, Reinaldo Dal, Forget, Antoine, Itzykson, Raphael, Ahn, Yeong-Ran, Dai, Ziwei, Sobhan, Raiyan T., Anderson, Gray R., Singleton, Katherine R., Decker, Amy E., Winter, Peter S., Locasale, Jason W., Crawford, Lorin, Puissant, Alexandre, Wood, Kris C.
Published in Nature genetics (01.04.2020)
Published in Nature genetics (01.04.2020)
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Abstract 264: The cell cycle checkpoint kinase 1/2 inhibitor, LY2606368 with PARP inhibition results in synergistic cytotoxicity in high-grade serous ovarian cancer (HGSOC) at lower than physiologically administered concentrations
Ahn, Yeong-ran, Yokoyama, Takuhei, Yu, Minshu, Gordon, Nicolas, Kohn, Elise C., Lee, Jung-min
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 264: The cell cycle checkpoint kinase 12 inhibitor, LY2606368 with PARP inhibition results in synergistic cytotoxicity in high-grade serous ovarian cancer (HGSOC) at lower than physiologically administered concentrations
Ahn, Yeong-ran, Yokoyama, Takuhei, Yu, Minshu, Gordon, Nicolas, Kohn, Elise C, Lee, Jung-min
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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