Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the "obesity paradox"
Vick, Logan V, Collins, Craig P, Khuat, Lam T, Wang, Ziming, Dunai, Cordelia, Aguilar, Ethan G, Stoffel, Kevin, Yendamuri, Sai, Smith, Jr, Randall, Mukherjee, Sarbajit, Barbi, Joseph, Canter, Robert J, Monjazeb, Arta M, Murphy, William J
Published in Frontiers in immunology (26.01.2023)
Published in Frontiers in immunology (26.01.2023)
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Targeting the Retinoid X Receptor Pathway Prevents and Ameliorates Murine Chronic Graft-Versus-Host Disease
Thangavelu, Govindarajan, Zaiken, Michael C, Mohamed, Fathima A, Flynn, Ryan, Du, Jing, Rhee, Stephanie Y, Riddle, Megan J, Aguilar, Ethan G, Panoskaltsis-Mortari, Angela, Sanders, Martin E, Blazar, Bruce R
Published in Frontiers in immunology (11.03.2022)
Published in Frontiers in immunology (11.03.2022)
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Regulation of human and mouse bystander T cell activation responses by PD-1
Le, Catherine T, Vick, Logan V, Collins, Craig, Dunai, Cordelia, Sheng, Michael K, Khuat, Lam T, Barao, Isabel, Judge, Sean J, Aguilar, Ethan G, Curti, Brendan, Dave, Maneesh, Longo, Dan L, Blazar, Bruce R, Canter, Robert J, Monjazeb, Arta M, Murphy, William J
Published in JCI insight (22.09.2023)
Published in JCI insight (22.09.2023)
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Journal Article
Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade
Wang, Ziming, Aguilar, Ethan G, Luna, Jesus I, Dunai, Cordelia, Khuat, Lam T, Le, Catherine T, Mirsoian, Annie, Minnar, Christine M, Stoffel, Kevin M, Sturgill, Ian R, Grossenbacher, Steven K, Withers, Sita S, Rebhun, Robert B, Hartigan-O'Connor, Dennis J, Méndez-Lagares, Gema, Tarantal, Alice F, Isseroff, R Rivkah, Griffith, Thomas S, Schalper, Kurt A, Merleev, Alexander, Saha, Asim, Maverakis, Emanual, Kelly, Karen, Aljumaily, Raid, Ibrahimi, Sami, Mukherjee, Sarbajit, Machiorlatti, Michael, Vesely, Sara K, Longo, Dan L, Blazar, Bruce R, Canter, Robert J, Murphy, William J, Monjazeb, Arta M
Published in Nature medicine (01.01.2019)
Published in Nature medicine (01.01.2019)
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Journal Article
Minimal PD-1 expression in mouse and human NK cells under diverse conditions
Judge, Sean J, Dunai, Cordelia, Aguilar, Ethan G, Vick, Sarah C, Sturgill, Ian R, Khuat, Lam T, Stoffel, Kevin M, Van Dyke, Jonathan, Longo, Dan L, Darrow, Morgan A, Anderson, Stephen K, Blazar, Bruce R, Monjazeb, Arta M, Serody, Jonathan S, Canter, Robert J, Murphy, William J
Published in The Journal of clinical investigation (01.06.2020)
Published in The Journal of clinical investigation (01.06.2020)
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Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism
Flynn, Ryan, Paz, Katelyn, Du, Jing, Reichenbach, Dawn K., Taylor, Patricia A., Panoskaltsis-Mortari, Angela, Vulic, Ante, Luznik, Leo, MacDonald, Kelli K.P., Hill, Geoffrey R., Nyuydzefe, Melanie S., Weiss, Jonathan M., Chen, Wei, Trzeciak, Alissa, Serody, Jon S., Aguilar, Ethan G., Murphy, William J., Maillard, Ivan, Munn, David, Koreth, John, Cutler, Corey S., Antin, Joseph H., Ritz, Jerome, Waksal, Samuel D., Zanin-Zhorov, Alexandra, Blazar, Bruce R.
Published in Blood (28.04.2016)
Published in Blood (28.04.2016)
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Journal Article
Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity
Larson, Jemma H., Jin, Sujeong, Loschi, Michael, Bolivar Wagers, Sara, Thangavelu, Govindarajan, Zaiken, Michael C., McDonald-Hyman, Cameron, Saha, Asim, Aguilar, Ethan G., Koehn, Brent, Osborn, Mark J., Panoskaltsis-Mortari, Angela, Macdonald, Kelli P.A., Hill, Geoffrey R., Murphy, William J., Serody, Jonathan S., Maillard, Ivan, Kean, Leslie S., Kim, Sangwon V., Littman, Dan R., Blazar, Bruce R.
Published in American journal of transplantation (01.08.2023)
Published in American journal of transplantation (01.08.2023)
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Journal Article
Leveraging natural killer cells for cancer immunotherapy
Grossenbacher, Steven K, Aguilar, Ethan G, Murphy, William J
Published in Immunotherapy (01.05.2017)
Published in Immunotherapy (01.05.2017)
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Journal Article
Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses
Thangavelu, Govindarajan, Wang, Chao, Loschi, Michael, Saha, Asim, Osborn, Mark J., Furlan, Scott N., Aoyama, Kazutoshi, McDonald-Hyman, Cameron, Aguilar, Ethan G., Janesick, Amanda S., Chandraratna, Roshantha A., Refaeli, Yosef, Panoskaltsis-Mortari, Angela, MacDonald, Kelli P., Hill, Geoffrey R., Zeiser, Robert, Maillard, Ivan, Serody, Jonathan S., Murphy, William J., Munn, David H., Blumberg, Bruce, Brown, Chrysothemis, Kuchroo, Vijay, Kean, Leslie S., Hippen, Keli L., Noelle, Randolph J., Blazar, Bruce R.
Published in Blood (25.02.2021)
Published in Blood (25.02.2021)
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Journal Article
Retinoic acid signaling acts as a rheostat to balance Treg function
Thangavelu, Govindarajan, Andrejeva, Gabriela, Bolivar-Wagers, Sara, Jin, Sujeong, Zaiken, Michael C, Loschi, Michael, Aguilar, Ethan G, Furlan, Scott N, Brown, Chrysothemis C, Lee, Yu-Chi, Hyman, Cameron McDonald, Feser, Colby J, Panoskaltsis-Mortari, Angela, Hippen, Keli L, MacDonald, Kelli P, Murphy, William J, Maillard, Ivan, Hill, Geoffrey R, Munn, David H, Zeiser, Robert, Kean, Leslie S, Rathmell, Jeffrey C, Chi, Hongbo, Noelle, Randolph J, Blazar, Bruce R
Published in Cellular & molecular immunology (01.07.2022)
Published in Cellular & molecular immunology (01.07.2022)
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Journal Article
Product Attributes of CAR T-cell Therapy Differentially Associate with Efficacy and Toxicity in Second-line Large B-cell Lymphoma (ZUMA-7)
Filosto, Simone, Vardhanabhuti, Saran, Canales, Miguel A, Poiré, Xavier, Lekakis, Lazaros J, de Vos, Sven, Portell, Craig A, Wang, Zixing, To, Christina, Schupp, Marco, Poddar, Soumya, Trinh, Tan, Warren, Carmen M, Aguilar, Ethan G, Budka, Justin, Cheng, Paul, Chou, Justin, Bot, Adrian, Shen, Rhine R, Westin, Jason R
Published in Blood cancer discovery (08.01.2024)
Published in Blood cancer discovery (08.01.2024)
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Journal Article
Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses
Bolivar-Wagers, Sara, Loschi, Michael L, Jin, Sujeong, Thangavelu, Govindarajan, Larson, Jemma H, McDonald-Hyman, Cameron S, Aguilar, Ethan G, Saha, Asim, Koehn, Brent H, Hefazi, Mehrdad, Osborn, Mark J, Jensen, Michael C, Wagner, John E, Pennell, Christopher A, Blazar, Bruce R
Published in JCI insight (08.09.2022)
Published in JCI insight (08.09.2022)
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Journal Article
Models to Study NK Cell Biology and Possible Clinical Application
Zamora, Anthony E, Grossenbacher, Steven K, Aguilar, Ethan G, Murphy, William J
Published in Current protocols in immunology (03.08.2015)
Published in Current protocols in immunology (03.08.2015)
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Journal Article
Activation status dictates the function of unlicensed natural killer cells in mice and humans
Aguilar, Ethan G., Dunai, Cordelia, Judge, Sean J., Zamora, Anthony E., Khuat, Lam T., Vick, Logan V., Collins, Craig P., Stoffel, Kevin M., Alvarez, Maite, Barao, Isabel, Miller, Jeffrey S., Blazar, Bruce R., Chevallier, Patrice, Retiere, Christelle, Canter, Robert J., Murphy, William J.
Published in Blood advances (26.10.2021)
Published in Blood advances (26.10.2021)
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Journal Article
Licensing delineates helper and effector NK cell subsets during viral infection
Zamora, Anthony E, Aguilar, Ethan G, Sungur, Can M, Khuat, Lam T, Dunai, Cordelia, Lochhead, G Raymond, Du, Juan, Pomeroy, Claire, Blazar, Bruce R, Longo, Dan L, Venstrom, Jeffrey M, Baumgarth, Nicole, Murphy, William J
Published in JCI insight (18.05.2017)
Published in JCI insight (18.05.2017)
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Journal Article
ACC1 Inhibition Enhances Treg Gvhd Treatment Efficacy through Regulation of Mitochondrial Fusion and Elongation
McDonald-Hyman, Cameron, Aguilar, Ethan G, Rhee, Stephanie Y, Mohamed, Fathima A, Compeer, Ewaldus, Sparwassar, Timothy, Dustin, Michael, Blazar, Bruce R
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Mitochondrial Pyruvate Carrier Inhibition Mitigates Murine Chronic Graft Versus Host Disease By Attenuating the Germinal Center Reaction
Mohamed, Fathima A, Rhee, Stephanie Y, Ly, Joanna, Aguilar, Ethan G, Melin, Haley, Sage, Peter T, Schumacher, Tanner, Thangavelu, Govindarajan, Zaiken, Michael C, Liu, Juan, Mereddy, Venkatram, Locasale, Jason W, Blazar, Bruce R
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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