Synaptic Dysfunction in Depression: Potential Therapeutic Targets
Duman, Ronald S., Aghajanian, George K.
Published in Science (American Association for the Advancement of Science) (05.10.2012)
Published in Science (American Association for the Advancement of Science) (05.10.2012)
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Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants
Duman, Ronald S, Aghajanian, George K, Sanacora, Gerard, Krystal, John H
Published in Nature medicine (01.03.2016)
Published in Nature medicine (01.03.2016)
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Journal Article
Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities
Shinohara, Ryota, Aghajanian, George K., Abdallah, Chadi G.
Published in Biological psychiatry (1969) (15.07.2021)
Published in Biological psychiatry (1969) (15.07.2021)
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Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions
Fuchikami, Manabu, Thomas, Alexandra, Liu, Rongjian, Wohleb, Eric S., Land, Benjamin B., DiLeone, Ralph J., Aghajanian, George K., Duman, Ronald S.
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (30.06.2015)
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Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex
Liu, Rong-Jian, Lee, Francis S, Li, Xiao-Yuan, Bambico, Francis, Duman, Ronald S, Aghajanian, George K
Published in Biological psychiatry (1969) (01.06.2012)
Published in Biological psychiatry (1969) (01.06.2012)
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GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine
LIU, Rong-Jian, FUCHIKAMI, Manabu, DWYER, Jason M, LEPACK, Ashley E, DUMAN, Ronald S, AGHAJANIAN, George K
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2013)
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2013)
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Journal Article
Signaling pathways underlying the rapid antidepressant actions of ketamine
Duman, Ronald S., Li, Nanxin, Liu, Rong-Jian, Duric, Vanja, Aghajanian, George
Published in Neuropharmacology (01.01.2012)
Published in Neuropharmacology (01.01.2012)
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Journal Article
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
Li, Nanxin, Lee, Boyoung, Liu, Rong-Jian, Banasr, Mounira, Dwyer, Jason M., Iwata, Masaaki, Li, Xiao-Yuan, Aghajanian, George, Duman, Ronald S.
Published in Science (American Association for the Advancement of Science) (20.08.2010)
Published in Science (American Association for the Advancement of Science) (20.08.2010)
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Glutamate N -methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure
Li, Nanxin, Liu, Rong-Jian, Dwyer, Jason M, Banasr, Mounira, Lee, Boyoung, Son, Hyeon, Li, Xiao-Yuan, Aghajanian, George, Duman, Ronald S
Published in Biological psychiatry (1969) (15.04.2011)
Published in Biological psychiatry (1969) (15.04.2011)
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REDD1 is essential for stress-induced synaptic loss and depressive behavior
Ota, Kristie T, Liu, Rong-Jian, Voleti, Bhavya, Maldonado-Aviles, Jaime G, Duric, Vanja, Iwata, Masaaki, Dutheil, Sophie, Duman, Catharine, Boikess, Steve, Lewis, David A, Stockmeier, Craig A, DiLeone, Ralph J, Rex, Christopher, Aghajanian, George K, Duman, Ronald S
Published in Nature medicine (01.05.2014)
Published in Nature medicine (01.05.2014)
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Journal Article
Scopolamine Rapidly Increases Mammalian Target of Rapamycin Complex 1 Signaling, Synaptogenesis, and Antidepressant Behavioral Responses
Voleti, Bhavya, Navarria, Andrea, Liu, Rong-Jian, Banasr, Mounira, Li, Nanxin, Terwilliger, Rose, Sanacora, Gerard, Eid, Tore, Aghajanian, George, Duman, Ronald S
Published in Biological psychiatry (1969) (15.11.2013)
Published in Biological psychiatry (1969) (15.11.2013)
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Journal Article
Medial prefrontal D1 dopamine neurons control food intake
Land, Benjamin B, Narayanan, Nandakumar S, Liu, Rong-Jian, Gianessi, Carol A, Brayton, Catherine E, Grimaldi, David M, Sarhan, Maysa, Guarnieri, Douglas J, Deisseroth, Karl, Aghajanian, George K, DiLeone, Ralph J
Published in Nature neuroscience (01.02.2014)
Published in Nature neuroscience (01.02.2014)
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Journal Article
Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses
Liu, Rong-Jian, Ota, Kristie T, Dutheil, Sophie, Duman, Ronald S, Aghajanian, George K
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2015)
Published in Neuropsychopharmacology (New York, N.Y.) (01.08.2015)
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Journal Article
Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β
DUMAN, Ronald S, AGHAJANIAN, George K
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2014)
Published in Neuropsychopharmacology (New York, N.Y.) (01.01.2014)
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Journal Article
Torgny Svensson, M.D., Ph.D. (1945–2020)
Aghajanian, George K, Mathé, Aleksander A, Eriksson, Elias, Krystal, John H
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2020)
Published in Neuropsychopharmacology (New York, N.Y.) (01.10.2020)
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Journal Article
Molecular and Cellular Basis of Addiction
Nestler, Eric J., Aghajanian, George K.
Published in Science (American Association for the Advancement of Science) (03.10.1997)
Published in Science (American Association for the Advancement of Science) (03.10.1997)
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Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone
Sears, Robert M, Liu, Rong-Jian, Narayanan, Nandakumar S, Sharf, Ruth, Yeckel, Mark F, Laubach, Mark, Aghajanian, George K, DiLeone, Ralph J
Published in The Journal of neuroscience (16.06.2010)
Published in The Journal of neuroscience (16.06.2010)
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