IL-17 integrates multiple self-reinforcing, feed-forward mechanisms through the RNA binding protein Arid5a
Amatya, Nilesh, Childs, Erin E, Cruz, J Agustin, Aggor, Felix E Y, Garg, Abhishek V, Berman, Andrea J, Gudjonsson, Johann E, Atasoy, Ulus, Gaffen, Sarah L
Published in Science signaling (09.10.2018)
Published in Science signaling (09.10.2018)
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IL-36 and IL-1/IL-17 Drive Immunity to Oral Candidiasis via Parallel Mechanisms
Verma, Akash H, Zafar, Hanna, Ponde, Nicole O, Hepworth, Olivia W, Sihra, Diksha, Aggor, Felix E Y, Ainscough, Joseph S, Ho, Jemima, Richardson, Jonathan P, Coleman, Bianca M, Hube, Bernhard, Stacey, Martin, McGeachy, Mandy J, Naglik, Julian R, Gaffen, Sarah L, Moyes, David L
Published in The Journal of immunology (1950) (15.07.2018)
Published in The Journal of immunology (1950) (15.07.2018)
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The Interleukin (IL) 17R/IL-22R Signaling Axis Is Dispensable for Vulvovaginal Candidiasis Regardless of Estrogen Status
Peters, Brian M, Coleman, Bianca M, Willems, Hubertine M E, Barker, Katherine S, Aggor, Felix E Y, Cipolla, Ellyse, Verma, Akash H, Bishu, Srinivas, Huppler, Anna H, Bruno, Vincent M, Gaffen, Sarah L
Published in The Journal of infectious diseases (07.04.2020)
Published in The Journal of infectious diseases (07.04.2020)
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Regnase-1 Deficiency Restrains Klebsiella pneumoniae Infection by Regulation of a Type I Interferon Response
Trevejo-Nuñez, Giraldina, Lin, Becky, Fan, Li, Aggor, Felix E Y, Biswas, Partha S, Chen, Kong, Gaffen, Sarah L
Published in mBio (01.02.2022)
Published in mBio (01.02.2022)
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The RNA binding protein Arid5a drives IL-17-dependent autoantibody-induced glomerulonephritis
Li, Yang, Vyas, Shachi P, Mehta, Isha, Asada, Nariaki, Dey, Ipsita, Taylor, Tiffany C, Bechara, Rami, Amatya, Nilesh, Aggor, Felix E Y, Coleman, Bianca M, Li, De-Dong, Yamamoto, Kenta, Ezenwa, Ogechukwu, Sun, Yeque, Sterneck, Esta, McManus, C Joel, Panzer, Ulf, Biswas, Partha S, Savan, Ram, Das, Jishnu, Gaffen, Sarah L
Published in The Journal of experimental medicine (02.09.2024)
Published in The Journal of experimental medicine (02.09.2024)
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An IL-17F.S65L Knock-In Mouse Reveals Similarities and Differences in IL-17F Function in Oral Candidiasis: A New Tool to Understand IL-17F
Zhou, Chunsheng, Monin, Leticia, Gordon, Rachael, Aggor, Felix E Y, Bechara, Rami, Edwards, Tara N, Kaplan, Daniel H, Gingras, Sebastien, Gaffen, Sarah L
Published in The Journal of immunology (1950) (01.08.2020)
Published in The Journal of immunology (1950) (01.08.2020)
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Interleukin-22 (IL-22) Binding Protein Constrains IL-22 Activity, Host Defense, and Oxidative Phosphorylation Genes during Pneumococcal Pneumonia
Trevejo-Nunez, Giraldina, Elsegeiny, Waleed, Aggor, Felix E Y, Tweedle, Jamie L, Kaplan, Zoe, Gandhi, Pranali, Castillo, Patricia, Ferguson, Annabel, Alcorn, John F, Chen, Kong, Kolls, Jay K, Gaffen, Sarah L
Published in Infection and immunity (01.11.2019)
Published in Infection and immunity (01.11.2019)
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Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis
Aggor, Felix E Y, Break, Timothy J, Trevejo-Nuñez, Giraldina, Whibley, Natasha, Coleman, Bianca M, Bailey, Rachel D, Kaplan, Daniel H, Naglik, Julian R, Shan, Wei, Shetty, Amol C, McCracken, Carrie, Durum, Scott K, Biswas, Partha S, Bruno, Vincent M, Kolls, Jay K, Lionakis, Michail S, Gaffen, Sarah L
Published in Science immunology (05.06.2020)
Published in Science immunology (05.06.2020)
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Identification of Plasmodium falciparum circumsporozoite protein-specific CD8+ T cell epitopes in a malaria exposed population
Kusi, Kwadwo A, Aggor, Felix E, Amoah, Linda E, Anum, Dorothy, Nartey, Yvonne, Amoako-Sakyi, Daniel, Obiri-Yeboah, Dorcas, Hollingdale, Michael, Ganeshan, Harini, Belmonte, Maria, Peters, Bjoern, Kim, Yohan, Tetteh, John, Kyei-Baafour, Eric, Dodoo, Daniel, Villasante, Eileen, Sedegah, Martha
Published in PloS one (10.02.2020)
Published in PloS one (10.02.2020)
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CYB5R3 T117S Genetic Mutation Is Associated With Major Adverse Cardiovascular and Cerebrovascular Events in Black Adults
Chaudhary, Rahul, Straub, Adam C, Aggor, Felix E Y, Onasanya, Ifeoluwa, Richardson, Jordan, Strollo, Patrick, Reis, Steven E, Olafiranye, Oladipupo
Published in Circulation. Genomic and precision medicine (01.04.2024)
Published in Circulation. Genomic and precision medicine (01.04.2024)
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A gut-oral microbiome-driven axis controls oropharyngeal candidiasis through retinoic acid
Aggor, Felix Ey, Bertolini, Martinna, Zhou, Chunsheng, Taylor, Tiffany C, Abbott, Darryl A, Musgrove, Javonn, Bruno, Vincent M, Hand, Timothy W, Gaffen, Sarah L
Published in JCI insight (22.09.2022)
Published in JCI insight (22.09.2022)
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The m 6 A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis
Bechara, Rami, Amatya, Nilesh, Bailey, Rachel D, Li, Yang, Aggor, Felix E Y, Li, De-Dong, Jawale, Chetan V, Coleman, Bianca M, Dai, Ning, Gokhale, Nandan S, Taylor, Tiffany C, Horner, Stacy M, Poholek, Amanda C, Bansal, Anita, Biswas, Partha S, Gaffen, Sarah L
Published in Science immunology (29.07.2021)
Published in Science immunology (29.07.2021)
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Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance
Millet, Nicolas, Sekar, Jinendiran, Solis, Norma V, Millet, Antoine, Aggor, Felix E Y, Wildeman, Asia, Lionakis, Michail S, Gaffen, Sarah L, Jendzjowsky, Nicholas, Filler, Scott G, Swidergall, Marc
Published in bioRxiv (13.09.2024)
Published in bioRxiv (13.09.2024)
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Th17-driven immunity to oral candidiasis is dependent on the microbiome and can be triggered by mono-colonization with segmented filamentous bacteria
Aggor, Felix E.Y., Zhou, Chunsheng, Abbott, Darryl, Musgrove, Javonn, Bruno, Vincent, Hand, Timothy W., Gaffen, Sarah L.
Published in The Journal of immunology (1950) (01.05.2022)
Published in The Journal of immunology (1950) (01.05.2022)
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Journal Article
An IL-17F.S65L knockin mouse reveals similarities and differences in IL-17F function in oral candidiasis: A new tool to understand IL-17F
Zhou, Chunsheng, Monin, Leticia, Gordon, Rachael, Aggor, Felix E.Y., Bechara, Rami, Edwards, Tara N., Kaplan, Daniel H., Gingras, Sebastien, Gaffen, Sarah L.
Published in The Journal of immunology (1950) (29.06.2020)
Published in The Journal of immunology (1950) (29.06.2020)
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Journal Article
A naturally-occurring mutation in IL-17F reveals a protective role for the IL-17AF heterodimer in oropharyngeal candidiasis (OPC)
Zhou, Chunsheng, Aggor, Felix E.Y., Monin, Leticia A, Gordon, Rachael A, Edwards, Tara N, Kaplan, Daniel H, Shlomchik, Mark J, Gingras, Sebastien, Gaffen, Sarah L
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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IL17 and Candida albicans colonization in the vaginal mucosa
Coleman, Bianca M, Peters, Brian M, Willems, Hubertine M.E., Barker, Katherine S., Aggor, Felix E.Y., Cipolla, Ellyse, Verma, Akash H, Bishu, Srinivas, Huppler, Anna H, Bruno, Vincent M, Childs, Erin E, Conti, Heather, Gaffen, Sarah L
Published in The Journal of immunology (1950) (01.05.2020)
Published in The Journal of immunology (1950) (01.05.2020)
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