Phase I trial of volasertib, a Polo-like kinase inhibitor, plus platinum agents in solid tumors: safety, pharmacokinetics and activity
Awada, Ahmad, Dumez, Herlinde, Aftimos, Philippe G., Costermans, Jo, Bartholomeus, Sylvie, Forceville, Kathleen, Berghmans, Thierry, Meeus, Marie-Anne, Cescutti, Jessica, Munzert, Gerd, Pilz, Korinna, Liu, Dan, Schöffski, Patrick
Published in Investigational new drugs (01.06.2015)
Published in Investigational new drugs (01.06.2015)
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Journal Article
Phase Ib Trial With Birabresib, a Small-Molecule Inhibitor of Bromodomain and Extraterminal Proteins, in Patients With Selected Advanced Solid Tumors
Lewin, Jeremy, Soria, Jean-Charles, Stathis, Anastasios, Delord, Jean-Pierre, Peters, Solange, Awada, Ahmad, Aftimos, Philippe G, Bekradda, Mohamed, Rezai, Keyvan, Zeng, Zhen, Hussain, Azher, Perez, Susan, Siu, Lillian L, Massard, Christophe
Published in Journal of clinical oncology (20.10.2018)
Published in Journal of clinical oncology (20.10.2018)
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Journal Article
Molecular biology in medical oncology: diagnosis, prognosis, and precision medicine
Aftimos, Philippe G, Barthelemy, Philippe, Awada, Ahmad
Published in Discovery medicine (01.02.2014)
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Published in Discovery medicine (01.02.2014)
Journal Article
Adjuvant chemo-radiation for gastric adenocarcinoma: an institutional experience
Aftimos, Philippe G, Nasr, Elie A, Nasr, Dolly I, Noun, Roger J, Nasr, Fady L, Ghosn, Marwan G, El Helou, Joelle A, Chahine, Georges Y
Published in Radiation oncology (London, England) (04.06.2010)
Published in Radiation oncology (London, England) (04.06.2010)
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Journal Article
Abstract 3962: Circulating tumor DNA (ctDNA) as an alternative to tumor biopsies for precision oncology: The Jules Bordet Institute experience
Aftimos, Philippe G., Maetens, Marion, Rothé, Françoise, Brown, David, Barèche, Yacine, Irrthum, Alexandre, Berghmans, Thierry, Kerger, Joseph, Hendlisz, Alain, Ignatiadis, Michail, Piccart, Martine, Sotiriou, Christos, Awada, Ahmad
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
Sequential use of protein kinase inhibitors potentiates their toxicity to melanoma cells: A rationale to combine targeted drugs based on protein expression inhibition profiles
AFTIMOS, PHILIPPE G, WIEDIG, MURIELLE, FONTSA, MIREILLE LANGOUO, AWADA, AHMAD, GHANEM, GHANEM, JOURNE, FABRICE
Published in International journal of oncology (01.09.2013)
Published in International journal of oncology (01.09.2013)
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Journal Article
A phase I, first-in-human study of argx-111, a monoclonal antibody targeting c-met in patients with solid tumors
Aftimos, Philippe G., Barthelemy, Philippe, Rolfo, Christian D., Hanssens, Valerie, De Jonge, Natalie, Silence, Karen, Dreier, Torsten, de Haard, Hans, Peeters, Marc, Thibault, Alain, Awada, Ahmad
Published in Journal of clinical oncology (20.05.2015)
Published in Journal of clinical oncology (20.05.2015)
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Journal Article
Abstract 3891: Tackling the obstacles facing the implementation of a molecular screening program in an early drug development unit: The Jules Bordet Institute Program for Molecular Profiling of Metastatic Lesions - feasibility (Precision-f)
Aftimos, Philippe G., Maetens, Marion, Sibille, Catherine, Laes, Jean-François, Brohée, Sylvain, Berghmans, Thierry, Kerger, Joseph, Hendlisz, Alain, Irrthum, Alexandre, De Henau, Olivier, Deleporte, Amélie, Drisis, Stylianos, Larsimont, Denis, Vakili, Jalal, Sotiriou, Christos, Piccart, Martine, Awada, Ahmad
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract P6-16-04: Phase 1/2a study of glutathione PEGylated liposomal doxorubicin (2B3-101) in breast cancer patients with brain metastases
Aftimos, Philippe G, Milojkovic-Kerklaan, Bojana, Diéras, Véronique, Altintas, Sevilay, Anders, Carey, Arnedos, Monica, Gelderblom, Hans, Soetekouw, Patricia, Gladdines, Werner, Gaillard, Pieter, de Sousa, Carlos, Jager, Agnes, van Linde, Myra, Awada, Ahmad, Schellens, Jan, Brandsma, Dieta
Published in Cancer research (Chicago, Ill.) (01.05.2015)
Published in Cancer research (Chicago, Ill.) (01.05.2015)
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Journal Article
Phase I dose-escalation study of an oral administration of the pan-histonedeacetylase inhibitor abexinostat combined with a fixed dose of doxorubicin in patients with solid tumors
Scherpereel, Arnaud, Awada, Ahmad, Gomez-Roca, Carlos Alberto, Wasielewski, Eric, Aftimos, Philippe G., Willemin, Marie-Capucine, Gil, Thierry, De Maio, Eleonora, Jozefowicz, Elsa, Kloos, Ioana, Dorbon, Alice, Cantero, Frédérique, Delord, Jean-Pierre
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
A phase I, first-in-human study of ARGX-110, a monoclonal antibody targeting CD70, a receptor involved in immune escape and tumor growth in patients with solid and hematologic malignancies
Awada, Ahmad, Rolfo, Christian D., Rottey, Sylvie, Ysebrant de Lendonck, Laure, Schroyens, Wilfried A., Offner, Fritz, Silence, Karen, Dreier, Torsten, Moshir, Mahan, de Haard, Hans, Peeters, Marc, Bron, Dominique, Thibault, Alain, Aftimos, Philippe G.
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article
PET/CT with 89Zr-trastuzumab and 18F-FDG to individualize treatment with trastuzumab emtansine (T-DM1) in metastatic HER2-positive breast cancer (mBC)
Gebhart, Geraldine, Lamberts, Laetitia E., Garcia, Camilo, Ameye, Lieveke, Stroobants, Sigrid, Huizing, Manon, Aftimos, Philippe G., Tol, Jolien, Oyen, Wim J.G., Wimana, Zena, Dongen, G.A.M.S. van, Hoekstra, Otto S., Schroder, Carolien P., Gaye, Julie, Menke, Catharina Wilhelmina, Guiot, Thomas, Brouwers, Adrienne H., Awada, Ahmad, de Vries, Elisabeth G. E., Flamen, Patrick
Published in Journal of clinical oncology (20.05.2014)
Published in Journal of clinical oncology (20.05.2014)
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Journal Article