Structural basis for RNA replication by the hepatitis C virus polymerase
Appleby, Todd C., Perry, Jason K., Murakami, Eisuke, Barauskas, Ona, Feng, Joy, Cho, Aesop, Fox, David, Wetmore, Diana R., McGrath, Mary E., Ray, Adrian S., Sofia, Michael J., Swaminathan, S., Edwards, Thomas E.
Published in Science (American Association for the Advancement of Science) (13.02.2015)
Published in Science (American Association for the Advancement of Science) (13.02.2015)
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Sensitivity of mitochondrial transcription and resistance of RNA polymerase II dependent nuclear transcription to antiviral ribonucleosides
Arnold, Jamie J, Sharma, Suresh D, Feng, Joy Y, Ray, Adrian S, Smidansky, Eric D, Kireeva, Maria L, Cho, Aesop, Perry, Jason, Vela, Jennifer E, Park, Yeojin, Xu, Yili, Tian, Yang, Babusis, Darius, Barauskus, Ona, Peterson, Blake R, Gnatt, Averell, Kashlev, Mikhail, Zhong, Weidong, Cameron, Craig E
Published in PLoS pathogens (01.11.2012)
Published in PLoS pathogens (01.11.2012)
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Metabolism and Pharmacokinetics of the Anti-Hepatitis C Virus Nucleotide Prodrug GS-6620
MURAKAMI, Eisuke, TING WANG, KIM, Choung U, AESOP CHO, RAY, Adrian S, BABUSIS, Darius, LEPIST, Eve-Irene, SAUER, Dorothea, YEOJIN PARK, VELA, Jennifer E, SHIH, Robert, BIRKUS, Gabriel, STEFANIDIS, Dimitrios
Published in Antimicrobial agents and chemotherapy (01.04.2014)
Published in Antimicrobial agents and chemotherapy (01.04.2014)
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Nucleotide Prodrug Containing a Nonproteinogenic Amino Acid To Improve Oral Delivery of a Hepatitis C Virus Treatment
Feng, Joy Y, Wang, Ting, Park, Yeojin, Babusis, Darius, Birkus, Gabriel, Xu, Yili, Voitenleitner, Christian, Fenaux, Martijn, Yang, Huiling, Eng, Stacey, Tirunagari, Neeraj, Kirschberg, Thorsten, Cho, Aesop, Ray, Adrian S
Published in Antimicrobial agents and chemotherapy (01.08.2018)
Published in Antimicrobial agents and chemotherapy (01.08.2018)
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Discovery of the First C‑Nucleoside HCV Polymerase Inhibitor (GS-6620) with Demonstrated Antiviral Response in HCV Infected Patients
Cho, Aesop, Zhang, Lijun, Xu, Jie, Lee, Rick, Butler, Thomas, Metobo, Sammy, Aktoudianakis, Vangelis, Lew, Willard, Ye, Hong, Clarke, Michael, Doerffler, Edward, Byun, Daniel, Wang, Ting, Babusis, Darius, Carey, Anne C., German, Polina, Sauer, Dorothea, Zhong, Weidong, Rossi, Stephen, Fenaux, Martijn, McHutchison, John G., Perry, Jason, Feng, Joy, Ray, Adrian S., Kim, Choung U.
Published in Journal of medicinal chemistry (13.03.2014)
Published in Journal of medicinal chemistry (13.03.2014)
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Synthesis and antiviral activity of a series of 1′-substituted 4-aza-7,9-dideazaadenosine C-nucleosides
Cho, Aesop, Saunders, Oliver L., Butler, Thomas, Zhang, Lijun, Xu, Jie, Vela, Jennifer E., Feng, Joy Y., Ray, Adrian S., Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.04.2012)
Published in Bioorganic & medicinal chemistry letters (15.04.2012)
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Preclinical characterization of a non-peptidomimetic HIV protease inhibitor with improved metabolic stability
Mulato, Andrew, Lansdon, Eric, Aoyama, Ron, Voigt, Johannes, Lee, Michael, Liclican, Albert, Lee, Gary, Singer, Eric, Stafford, Brian, Gong, Ruoyu, Murray, Bernard, Chan, Julie, Lee, Johnny, Xu, Yili, Ahmadyar, Shekeba, Gonzalez, Ana, Cho, Aesop, Stepan, George J, Schmitz, Uli, Schultz, Brian, Marchand, Bruno, Brumshtein, Boris, Wang, Ruth, Yu, Helen, Cihlar, Tomas, Xu, Lianhong, Yant, Stephen R
Published in Antimicrobial agents and chemotherapy (03.04.2024)
Published in Antimicrobial agents and chemotherapy (03.04.2024)
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Journal Article
Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug
FENG, Joy Y, GUOFENG CHENG, YANG TIAN, LEE, Yu-Jen, STEPAN, George, LAGPACAN, Leanna L, DEBI JIN, HUNG, Magdeleine, KU, Karin S, BIN HAN, KITRINOS, Kathryn, PERRON, Michel, PERRY, Jason, BIRKUS, Gabriel, WONG, Kelly A, WEIDONG ZHONG, KIM, Choung U, CAREY, Anne, AESOP CHO, RAY, Adrian S, BARAUSKAS, Ona, YILI XU, FENAUX, Martijn, ENG, Stacey, TIRUNAGARI, Neeraj, BETTY PENG, MEI YU
Published in Antimicrobial agents and chemotherapy (01.04.2014)
Published in Antimicrobial agents and chemotherapy (01.04.2014)
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Practical synthesis of 1′-substituted Tubercidin C-nucleoside analogs
Metobo, Sammy E., Xu, Jie, Saunders, Oliver L., Butler, Thomas, Aktoudianakis, Evangelos, Cho, Aesop, Kim, Choung U.
Published in Tetrahedron letters (01.02.2012)
Published in Tetrahedron letters (01.02.2012)
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Journal Article
Synthesis of 1-amino-2-vinylcyclopropane-1-phosphinates. Conversion of a phosphonate to phosphinates
Pyun, Hyung-Jung, Clarke, Michael O., Cho, Aesop, Casarez, Anthony, Ji, Mingzhe, Fardis, Maria, Pastor, Richard, Sheng, X. Christopher, Kim, Choung U.
Published in Tetrahedron letters (02.05.2012)
Published in Tetrahedron letters (02.05.2012)
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Journal Article
Synthesis and characterization of 2′-C-Me branched C-nucleosides as HCV polymerase inhibitors
Cho, Aesop, Zhang, Lijun, Xu, Jie, Babusis, Darius, Butler, Thomas, Lee, Rick, Saunders, Oliver L., Wang, Ting, Parrish, Jay, Perry, Jason, Feng, Joy Y., Ray, Adrian S., Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
Published in Bioorganic & medicinal chemistry letters (15.06.2012)
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