Evolution of Mammalian Chitinase(-Like) Members of Family 18 Glycosyl Hydrolases
Bussink, Anton P, Speijer, Dave, Aerts, Johannes M. F. G, Boot, Rolf G
Published in Genetics (Austin) (01.10.2007)
Published in Genetics (Austin) (01.10.2007)
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Functionalized Cyclophellitols Are Selective Glucocerebrosidase Inhibitors and Induce a Bona Fide Neuropathic Gaucher Model in Zebrafish
Artola, Marta, Kuo, Chi-Lin, Lelieveld, Lindsey T, Rowland, Rhianna J, van der Marel, Gijsbert A, Codée, Jeroen D. C, Boot, Rolf G, Davies, Gideon J, Aerts, Johannes M. F. G, Overkleeft, Herman S
Published in Journal of the American Chemical Society (13.03.2019)
Published in Journal of the American Chemical Society (13.03.2019)
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Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases
Ferraz, Maria J., Marques, André R. A., Appelman, Monique D., Verhoek, Marri, Strijland, Anneke, Mirzaian, Mina, Scheij, Saskia, Ouairy, Cécile M., Lahav, Daniel, Wisse, Patrick, Overkleeft, Herman S., Boot, Rolf G., Aerts, Johannes M.
Published in FEBS letters (01.03.2016)
Published in FEBS letters (01.03.2016)
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a-Synuclein and lipids in erythrocytes of Gaucher disease carriers and patients before and after enzyme replacement therapy
Moraitou, Marina, Sotiroudis, Georgios, Papagiannakis, Nikolaos, Ferraz, Maria M J, Xenakis, Aristotelis, Aerts, Johannes M F G, Stefanis, Leonidas, Michelakakis, Helen
Published in PloS one (03.02.2023)
Published in PloS one (03.02.2023)
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Glycosphingolipids-Nature, Function, and Pharmacological Modulation
Wennekes, Tom, van den Berg, Richard J. B. H. N., Boot, Rolf G., van der Marel, Gijsbert A., Overkleeft, Herman S., Aerts, Johannes M. F. G.
Published in Angewandte Chemie International Edition (09.11.2009)
Published in Angewandte Chemie International Edition (09.11.2009)
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LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance
Rothaug, Michelle, Zunke, Friederike, Mazzulli, Joseph R., Schweizer, Michaela, Altmeppen, Hermann, Lüllmann-Rauch, Renate, Kallemeijn, Wouter W., Gaspar, Paulo, Aerts, Johannes M., Glatzel, Markus, Saftig, Paul, Krainc, Dimitri, Schwake, Michael, Blanz, Judith
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (28.10.2014)
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Fluorescence polarisation activity-based protein profiling for the identification of deoxynojirimycin-type inhibitors selective for lysosomal retaining alpha- and beta-glucosidases
van der Gracht, Daniël, Rowland, Rhianna J, Roig-Zamboni, Véronique, Ferraz, Maria J, Louwerse, Max, Geurink, Paul P, Aerts, Johannes M. F. G, Sulzenbacher, Gerlind, Davies, Gideon J, Overkleeft, Herman S, Artola, Marta
Published in Chemical science (Cambridge) (30.08.2023)
Published in Chemical science (Cambridge) (30.08.2023)
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Long-term effect of antibodies against infused alpha-galactosidase A in Fabry disease on plasma and urinary (lyso)Gb3 reduction and treatment outcome
Rombach, Saskia M, Aerts, Johannes M F G, Poorthuis, Ben J H M, Groener, Johanna E M, Donker-Koopman, Wilma, Hendriks, Erik, Mirzaian, Mina, Kuiper, Sijmen, Wijburg, Frits A, Hollak, Carla E M, Linthorst, Gabor E
Published in PloS one (19.10.2012)
Published in PloS one (19.10.2012)
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Establishing 3-nitrotyrosine as a biomarker for the vasculopathy of Fabry disease
Shu, Liming, Vivekanandan-Giri, Anuradha, Pennathur, Subramaniam, Smid, Bouwien E., Aerts, Johannes M.F.G., Hollak, Carla E.M., Shayman, James A.
Published in Kidney international (01.07.2014)
Published in Kidney international (01.07.2014)
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Journal Article
Elevated globotriaosylsphingosine is a hallmark of Fabry disease
Aerts, Johannes M, Groener, Johanna E, Kuiper, Sijmen, Donker-Koopman, Wilma E, Strijland, Anneke, Ottenhoff, Roelof, van Roomen, Cindy, Mirzaian, Mina, Wijburg, Frits A, Linthorst, Gabor E, Vedder, Anouk C, Rombach, Saskia M, Cox-Brinkman, Josanne, Somerharju, Pentti, Boot, Rolf G, Hollak, Carla E, Brady, Roscoe O, Poorthuis, Ben J
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2008)
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Animal Models for the Study of Gaucher Disease
Cabasso, Or, Kuppuramalingam, Aparna, Lelieveld, Lindsey, Van der Lienden, Martijn, Boot, Rolf, Aerts, Johannes M., Horowitz, Mia
Published in International journal of molecular sciences (01.11.2023)
Published in International journal of molecular sciences (01.11.2023)
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Elevated plasma glucosylsphingosine in Gaucher disease: relation to phenotype, storage cell markers, and therapeutic response
Dekker, Nick, van Dussen, Laura, Hollak, Carla E.M., Overkleeft, Herman, Scheij, Saskia, Ghauharali, Karen, van Breemen, Mariëlle J., Ferraz, Maria J., Groener, Johanna E.M., Maas, Mario, Wijburg, Frits A., Speijer, Dave, Tylki-Szymanska, Anna, Mistry, Pramod K., Boot, Rolf G., Aerts, Johannes M.
Published in Blood (20.10.2011)
Published in Blood (20.10.2011)
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Induction of Sphk1 activity in obese adipose tissue macrophages promotes survival
Gabriel, Tanit L, Mirzaian, Mina, Hooibrink, Berend, Ottenhoff, Roelof, van Roomen, Cindy, Aerts, Johannes M F G, van Eijk, Marco
Published in PloS one (28.07.2017)
Published in PloS one (28.07.2017)
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Manno-epi-cyclophellitols Enable Activity-Based Protein Profiling of Human α‑Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors
Armstrong, Zachary, Kuo, Chi-Lin, Lahav, Daniël, Liu, Bing, Johnson, Rachel, Beenakker, Thomas J. M, de Boer, Casper, Wong, Chung-Sing, van Rijssel, Erwin R, Debets, Marjoke F, Florea, Bogdan I, Hissink, Colin, Boot, Rolf G, Geurink, Paul P, Ovaa, Huib, van der Stelt, Mario, van der Marel, Gijsbert M, Codée, Jeroen D. C, Aerts, Johannes M. F. G, Wu, Liang, Overkleeft, Herman S, Davies, Gideon J
Published in Journal of the American Chemical Society (29.07.2020)
Published in Journal of the American Chemical Society (29.07.2020)
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Activity-Based Protein Profiling of Retaining α‑Amylases in Complex Biological Samples
Chen, Yurong, Armstrong, Zachary, Artola, Marta, Florea, Bogdan I, Kuo, Chi-Lin, de Boer, Casper, Rasmussen, Mikkel S, Abou Hachem, Maher, van der Marel, Gijsbert A, Codée, Jeroen D. C, Aerts, Johannes M. F. G, Davies, Gideon J, Overkleeft, Herman S
Published in Journal of the American Chemical Society (10.02.2021)
Published in Journal of the American Chemical Society (10.02.2021)
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Gpnmb Is a Potential Marker for the Visceral Pathology in Niemann-Pick Type C Disease
Marques, André R A, Gabriel, Tanit L, Aten, Jan, van Roomen, Cindy P A A, Ottenhoff, Roelof, Claessen, Nike, Alfonso, Pilar, Irún, Pilar, Giraldo, Pilar, Aerts, Johannes M F G, van Eijk, Marco
Published in PloS one (15.01.2016)
Published in PloS one (15.01.2016)
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Plant Glycosides and Glycosidases: A Treasure-Trove for Therapeutics
Kytidou, Kassiani, Artola, Marta, Overkleeft, Herman S, Aerts, Johannes M F G
Published in Frontiers in plant science (07.04.2020)
Published in Frontiers in plant science (07.04.2020)
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The development of a broad-spectrum retaining β-exo-galactosidase activity-based probe
Kuo, Chi-Lin, Su, Qin, van den Nieuwendijk, Adrianus M. C. H, Beenakker, Thomas J. M, Offen, Wendy A, Willems, Lianne I, Boot, Rolf. G, Sarris, Alexi J, Marques, André R. A, Codée, Jeroen D. C, van der Marel, Gijsbert A, Florea, Bogdan I, Davies, Gideon J, Overkleeft, Herman S, Aerts, Johannes M. F. G
Published in Organic & biomolecular chemistry (04.10.2023)
Published in Organic & biomolecular chemistry (04.10.2023)
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The Unique Phenotype of Lipid-Laden Macrophages
van Eijk, Marco, Aerts, Johannes M F G
Published in International journal of molecular sciences (14.04.2021)
Published in International journal of molecular sciences (14.04.2021)
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