Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration
Fetiva, Maria Camila, Liss, Franziska, Gertzmann, Dörthe, Thomas, Julius, Gantert, Benedikt, Vogl, Magdalena, Sira, Nataliia, Weinstock, Grit, Kneitz, Susanne, Ade, Carsten P, Gaubatz, Stefan
Published in Nucleic acids research (22.05.2023)
Published in Nucleic acids research (22.05.2023)
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NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas
Meder, Lydia, König, Katharina, Ozretić, Luka, Schultheis, Anne M., Ueckeroth, Frank, Ade, Carsten P., Albus, Kerstin, Boehm, Diana, Rommerscheidt‐Fuss, Ursula, Florin, Alexandra, Buhl, Theresa, Hartmann, Wolfgang, Wolf, Jürgen, Merkelbach‐Bruse, Sabine, Eilers, Martin, Perner, Sven, Heukamp, Lukas C., Buettner, Reinhard
Published in International journal of cancer (15.02.2016)
Published in International journal of cancer (15.02.2016)
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Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress
Kaymak, Irem, Maier, Carina R, Schmitz, Werner, Campbell, Andrew D, Dankworth, Beatrice, Ade, Carsten P, Walz, Susanne, Paauwe, Madelon, Kalogirou, Charis, Marouf, Hecham, Rosenfeldt, Mathias T, Gay, David M, McGregor, Grace H, Sansom, Owen J, Schulze, Almut
Published in Cancer research (Chicago, Ill.) (15.01.2020)
Published in Cancer research (Chicago, Ill.) (15.01.2020)
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The transcription factor NRF2 enhances melanoma malignancy by blocking differentiation and inducing COX2 expression
Jessen, Christina, Kreß, Julia K. C., Baluapuri, Apoorva, Hufnagel, Anita, Schmitz, Werner, Kneitz, Susanne, Roth, Sabine, Marquardt, André, Appenzeller, Silke, Ade, Carsten P., Glutsch, Valerie, Wobser, Marion, Friedmann-Angeli, José Pedro, Mosteo, Laura, Goding, Colin R., Schilling, Bastian, Geissinger, Eva, Wolf, Elmar, Meierjohann, Svenja
Published in Oncogene (29.10.2020)
Published in Oncogene (29.10.2020)
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Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes
Gründl, Marco, Walz, Susanne, Hauf, Laura, Schwab, Melissa, Werner, Kerstin Marcela, Spahr, Susanne, Schulte, Clemens, Maric, Hans Michael, Ade, Carsten P, Gaubatz, Stefan
Published in PLoS genetics (01.05.2020)
Published in PLoS genetics (01.05.2020)
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The adrenergic-induced ERK3 pathway drives lipolysis and suppresses energy dissipation
El-Merahbi, Rabih, Viera, Jonathan Trujillo, Valdes, Angel Loza, Kolczynska, Katarzyna, Reuter, Saskia, Löffler, Mona C, Erk, Manuela, Ade, Carsten P, Karwen, Till, Mayer, Alexander E, Eilers, Martin, Sumara, Grzegorz
Published in Genes & development (01.04.2020)
Published in Genes & development (01.04.2020)
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PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma
Gaballa, Abdallah, Gebhardt-Wolf, Anneli, Krenz, Bastian, Mattavelli, Greta, John, Mara, Cossa, Giacomo, Andreani, Silvia, Schülein-Völk, Christina, Montesinos, Francisco, Vidal, Raphael, Kastner, Carolin, Ade, Carsten P., Kneitz, Burkhard, Gasteiger, Georg, Gallant, Peter, Rosenfeldt, Mathias, Riedel, Angela, Eilers, Martin
Published in Nature communications (16.02.2024)
Published in Nature communications (16.02.2024)
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The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes
Pattschull, Grit, Walz, Susanne, Gründl, Marco, Schwab, Melissa, Rühl, Eva, Baluapuri, Apoorva, Cindric-Vranesic, Anita, Kneitz, Susanne, Wolf, Elmar, Ade, Carsten P., Rosenwald, Andreas, von Eyss, Björn, Gaubatz, Stefan
Published in Cell reports (Cambridge) (18.06.2019)
Published in Cell reports (Cambridge) (18.06.2019)
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Intracellular Staphylococcus aureus Perturbs the Host Cell Ca2+ Homeostasis To Promote Cell Death
Stelzner, Kathrin, Winkler, Ann-Cathrin, Liang, Chunguang, Boyny, Aziza, Ade, Carsten P, Dandekar, Thomas, Fraunholz, Martin J, Rudel, Thomas
Published in mBio (15.12.2020)
Published in mBio (15.12.2020)
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Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells
Prieto‐Garcia, Cristian, Hartmann, Oliver, Reissland, Michaela, Braun, Fabian, Fischer, Thomas, Walz, Susanne, Schülein‐Völk, Christina, Eilers, Ursula, Ade, Carsten P, Calzado, Marco A, Orian, Amir, Maric, Hans M, Münch, Christian, Rosenfeldt, Mathias, Eilers, Martin, Diefenbacher, Markus E
Published in EMBO molecular medicine (07.04.2020)
Published in EMBO molecular medicine (07.04.2020)
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Tumor cell‐specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase
Peter, Stefanie, Bultinck, Jennyfer, Myant, Kevin, Jaenicke, Laura A, Walz, Susanne, Müller, Judith, Gmachl, Michael, Treu, Matthias, Boehmelt, Guido, Ade, Carsten P, Schmitz, Werner, Wiegering, Armin, Otto, Christoph, Popov, Nikita, Sansom, Owen, Kraut, Norbert, Eilers, Martin
Published in EMBO molecular medicine (01.12.2014)
Published in EMBO molecular medicine (01.12.2014)
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RNA polymerase I inhibition induces terminal differentiation, growth arrest, and vulnerability to senolytics in colorectal cancer cells
Otto, Christoph, Kastner, Carolin, Schmidt, Stefanie, Uttinger, Konstantin, Baluapuri, Apoorva, Denk, Sarah, Rosenfeldt, Mathias T., Rosenwald, Andreas, Roehrig, Florian, Ade, Carsten P., Schuelein‐Voelk, Christina, Diefenbacher, Markus E., Germer, Christoph‐Thomas, Wolf, Elmar, Eilers, Martin, Wiegering, Armin
Published in Molecular oncology (01.08.2022)
Published in Molecular oncology (01.08.2022)
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Expression of the cytokinesis regulator PRC1 results in p53-pathway activation in A549 cells but does not directly regulate gene expression in the nucleus
Hanselmann, Steffen, Gertzmann, Dörthe, Shin, Woo Jin, Ade, Carsten P., Gaubatz, Stefan
Published in Cell cycle (Georgetown, Tex.) (16.02.2023)
Published in Cell cycle (Georgetown, Tex.) (16.02.2023)
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Recruitment of BRCA1 limits MYCN-driven accumulation of stalled RNA polymerase
Herold, Steffi, Kalb, Jacqueline, Büchel, Gabriele, Ade, Carsten P., Baluapuri, Apoorva, Xu, Jiajia, Koster, Jan, Solvie, Daniel, Carstensen, Anne, Klotz, Christina, Rodewald, Sabrina, Schülein-Völk, Christina, Dobbelstein, Matthias, Wolf, Elmar, Molenaar, Jan, Versteeg, Rogier, Walz, Susanne, Eilers, Martin
Published in Nature (London) (01.03.2019)
Published in Nature (London) (01.03.2019)
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NEAT1 promotes genome stability via m 6 A methylation-dependent regulation of CHD4
Mamontova, Victoria, Trifault, Barbara, Gribling-Burrer, Anne-Sophie, Bohn, Patrick, Boten, Lea, Preckwinkel, Pit, Gallant, Peter, Solvie, Daniel, Ade, Carsten P, Papadopoulos, Dimitrios, Eilers, Martin, Gutschner, Tony, Smyth, Redmond P, Burger, Kaspar
Published in Genes & development (03.10.2024)
Published in Genes & development (03.10.2024)
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The MYC mRNA 3′‐UTR couples RNA polymerase II function to glutamine and ribonucleotide levels
Dejure, Francesca R, Royla, Nadine, Herold, Steffi, Kalb, Jacqueline, Walz, Susanne, Ade, Carsten P, Mastrobuoni, Guido, Vanselow, Jens T, Schlosser, Andreas, Wolf, Elmar, Kempa, Stefan, Eilers, Martin
Published in The EMBO journal (03.07.2017)
Published in The EMBO journal (03.07.2017)
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Nucleolar detention of NONO shields DNA double-strand breaks from aberrant transcripts
Trifault, Barbara, Mamontova, Victoria, Cossa, Giacomo, Ganskih, Sabina, Wei, Yuanjie, Hofstetter, Julia, Bhandare, Pranjali, Baluapuri, Apoorva, Nieto, Blanca, Solvie, Daniel, Ade, Carsten P, Gallant, Peter, Wolf, Elmar, Larsen, Dorthe H, Munschauer, Mathias, Burger, Kaspar
Published in Nucleic acids research (12.04.2024)
Published in Nucleic acids research (12.04.2024)
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Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers
Jessen, Marco, Gertzmann, Dörthe, Liss, Franziska, Zenk, Franziska, Bähner, Laura, Schöffler, Victoria, Schulte, Clemens, Maric, Hans Michael, Ade, Carsten P., von Eyss, Björn, Gaubatz, Stefan
Published in Oncogene (16.02.2024)
Published in Oncogene (16.02.2024)
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Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters
Endres, Theresa, Solvie, Daniel, Heidelberger, Jan B., Andrioletti, Valentina, Baluapuri, Apoorva, Ade, Carsten P., Muhar, Matthias, Eilers, Ursula, Vos, Seychelle M., Cramer, Patrick, Zuber, Johannes, Beli, Petra, Popov, Nikita, Wolf, Elmar, Gallant, Peter, Eilers, Martin
Published in Molecular cell (18.02.2021)
Published in Molecular cell (18.02.2021)
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MYC- and MIZ1-Dependent Vesicular Transport of Double-Strand RNA Controls Immune Evasion in Pancreatic Ductal Adenocarcinoma
Krenz, Bastian, Gebhardt-Wolf, Anneli, Ade, Carsten P, Gaballa, Abdallah, Roehrig, Florian, Vendelova, Emilia, Baluapuri, Apoorva, Eilers, Ursula, Gallant, Peter, D'Artista, Luana, Wiegering, Armin, Gasteiger, Georg, Rosenfeldt, Mathias T, Bauer, Stefan, Zender, Lars, Wolf, Elmar, Eilers, Martin
Published in Cancer research (Chicago, Ill.) (15.08.2021)
Published in Cancer research (Chicago, Ill.) (15.08.2021)
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