Targeting Macromolecules to CNS and Other Hard-to-Treat Organs Using Lectin-Mediated Delivery
Acosta, Walter, Cramer, Carole L
Published in International journal of molecular sciences (01.02.2020)
Published in International journal of molecular sciences (01.02.2020)
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Journal Article
Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis
Weesner, Jason Andrew, Annunziata, Ida, Yang, Tianhong, Acosta, Walter, Gomero, Elida, Hu, Huimin, van de Vlekkert, Diantha, Ayala, Jorge, Qiu, Xiaohui, Fremuth, Leigh Ellen, Radin, David N, Cramer, Carole L, d'Azzo, Alessandra
Published in Cells (Basel, Switzerland) (01.08.2022)
Published in Cells (Basel, Switzerland) (01.08.2022)
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Journal Article
A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease
Westbroek, Wendy, Nguyen, Matthew, Siebert, Marina, Lindstrom, Taylor, Burnett, Robert A, Aflaki, Elma, Jung, Olive, Tamargo, Rafael, Rodriguez-Gil, Jorge L, Acosta, Walter, Hendrix, An, Behre, Bahafta, Tayebi, Nahid, Fujiwara, Hideji, Sidhu, Rohini, Renvoise, Benoit, Ginns, Edward I, Dutra, Amalia, Pak, Evgenia, Cramer, Carole, Ory, Daniel S, Pavan, William J, Sidransky, Ellen
Published in Disease models & mechanisms (01.07.2016)
Published in Disease models & mechanisms (01.07.2016)
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Journal Article
South American giant short-faced bear (Arctotherium angustidens) diet: evidence from pathology, morphology, stable isotopes, and biomechanics
Soibelzon, Leopoldo H, Grinspan, Gustavo A, Bocherens, Hervé, Acosta, Walter G, Jones, Washington, Blanco, Ernesto R, Prevosti, Francisco
Published in Journal of paleontology (01.11.2014)
Published in Journal of paleontology (01.11.2014)
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Journal Article
High-throughput imaging method for direct assessment of GM1 ganglioside levels in mammalian cells
Acosta, Walter, Martin, Reid, Radin, David N., Cramer, Carole L.
Published in Data in brief (01.03.2016)
Published in Data in brief (01.03.2016)
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Journal Article
Intracellular stability and efficacy of β-galactosidase fusions as a GM1 gangliosidosis ERT are significantly influenced by mouse versus human multi-enzyme complex interactions
Yang, Tianhong, Acosta, Walter L., Ayala, Jorge, Pattada, Shivakumar, Riley, Kassandra, Hampton, Rachel, Radin, David, Cramer, Carole L.
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
RTB-lectin facilitates the distribution of enzymes across the blood-brain-barrier and correction in the MPS IIIA mouse model
Pattada, Shivakumar D., Ayala, Jorge, Acosta, Walter L., Yang, Tianhong, Riley, Kassandra, Hampton, Rachel, Hampton, Eddie J., Cramer, Carole L., Radin, David
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Preclinical enzyme replacement therapy with a recombinant β-galactosidase-lectin fusion for CNS delivery and treatment of GM1-gangliosidosis
Weesner, Jason A., van de Vlekkert, Diantha, Acosta, Walter L., Yang, Tianhong, Gomero, Elida M., Hu, Huimin, Radin, David, Cramer, Carole L., d'Azzo, Alessandra
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
RTB Lectin: a novel receptor-independent delivery system for lysosomal enzyme replacement therapies
Acosta, Walter, Ayala, Jorge, Dolan, Maureen C., Cramer, Carole L.
Published in Scientific reports (18.09.2015)
Published in Scientific reports (18.09.2015)
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Journal Article
Enzyme replacement for GM1-gangliosidosis: Uptake, lysosomal activation, and cellular disease correction using a novel β-galactosidase:RTB lectin fusion
Condori, Jose, Acosta, Walter, Ayala, Jorge, Katta, Varun, Flory, Ashley, Martin, Reid, Radin, Jonathan, Cramer, Carole L., Radin, David N.
Published in Molecular genetics and metabolism (01.02.2016)
Published in Molecular genetics and metabolism (01.02.2016)
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Journal Article
Lectin-mediated delivery to tissues and organs affected by the development of anti-drug antibodies in MPS I mouse model
Acosta, Walter, Hampton, Rachel, Ayala, Jorge, Pattada, Shivakumar, Riley, Kassandra, Yang, Tianhong, Hampton, Eddie J., Sanchez, Luis M., Cubero, Maria, Cofre, Carmela Unnold, Martin, Reid, Solano, Aura D., Radin, David, Cramer, Carole L.
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Correction of bone pathology in MPS I mouse model using lectin-mediated delivery
Acosta, Walter L., Hampton, Rachel, Ayala, Jorge, Yang, Tianhong, Pattada, Shivakumar, Riley, Kassandra, Hampton, Eddie J., Cubero, Maria Fernanda, Sanchez, Luis M., Cofre, Carmela Unnold, Martin, Reid, Solano, Aura D., Radin, David, Cramer, Carole L.
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
Physiological Response and Multi-Elemental Content in Lichens Growing on Agricultural Fences: A Pilot Study Comparing No-Tillage and Organic Cropping
Filippini, Edith, Cañas, Martha, Acosta, Walter Daniel, Plá, Rita Rosa, Jasan, Raquel Clara, Invernizzi, Rodrigo, Estrabou, Cecilia
Published in Bulletin of environmental contamination and toxicology (01.08.2020)
Published in Bulletin of environmental contamination and toxicology (01.08.2020)
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Journal Article
Receptor-independent mechanisms of RTB lectin-mediated ERT delivery provide unique advantages in enzyme uptake capacity, transcytosis, and lysosomal correction
Martin, Reid, Acosta, Walter, Ayala, Jorge, Katta, Varun, Flory, Ashley, Radin, Jonathan, Devaiah, Shivakumar, Cramer, Carole, Radin, David
Published in Molecular genetics and metabolism (01.01.2017)
Published in Molecular genetics and metabolism (01.01.2017)
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Journal Article
Novel bioproduction and delivery strategies for MPS IIIA enzyme replacement therapeutics
Condori, Jose, Katta, Varun, Acosta, Walter, Ayala, Jorge, Flory, Ashley, Radin, Jonathan, Davis, Samantha, Cramer, Carole L., Radin, David N.
Published in Molecular genetics and metabolism (01.02.2016)
Published in Molecular genetics and metabolism (01.02.2016)
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Journal Article
Enzyme replacement therapy with α-L-iduronidase and lectin RTB fusion protein in treating murine Hurler syndrome
Ou, Li, Acosta, Walter, Koniar, Brenda L., Cooksley, Renee D., Cramer, Carole L., Radin, David N., Whitley, Chester B.
Published in Molecular genetics and metabolism (01.02.2016)
Published in Molecular genetics and metabolism (01.02.2016)
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Journal Article
Rectitis estenosante inflamatoria
Ruben Gary, Walter Acosta Ferreira, Enrique Capandeguy
Published in Cirugia del Uruguay (01.02.2021)
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Published in Cirugia del Uruguay (01.02.2021)
Journal Article
Colangiopatía uremígena (síndrome de Varela Fuentes)
Ruben Gary, Federico Latourrette, Walter Acosta Ferreira
Published in Cirugia del Uruguay (01.08.2020)
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Published in Cirugia del Uruguay (01.08.2020)
Journal Article
Uptake, lysosomal activation, and disease correction in GM1 Gangliosidosis cells by plant-made β-galactosidase: Lectin fusions
Ayala, Jorge, Acosta, Walter, Condori, Jose, Annunziata, Ida, Katta, Varun, Flory, Ashley, Martin, Reid, Radin, Jonathan, Cramer, Carole L., d'Azzo, Alessandra, Radin, David N.
Published in Molecular genetics and metabolism (01.02.2016)
Published in Molecular genetics and metabolism (01.02.2016)
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Journal Article