A Novel Approach to Predicting P450 Mediated Drug Metabolism. CYP2D6 Catalyzed N-Dealkylation Reactions and Qualitative Metabolite Predictions Using a Combined Protein and Pharmacophore Model for CYP2D6
de Groot, Marcel J, Ackland, Mark J, Horne, Valerie A, Alex, Alexander A, Jones, Barry C
Published in Journal of medicinal chemistry (07.10.1999)
Published in Journal of medicinal chemistry (07.10.1999)
Get full text
Journal Article
Novel Approach To Predicting P450-Mediated Drug Metabolism: Development of a Combined Protein and Pharmacophore Model for CYP2D6
de Groot, Marcel J, Ackland, Mark J, Horne, Valerie A, Alex, Alexander A, Jones, Barry C
Published in Journal of medicinal chemistry (06.05.1999)
Published in Journal of medicinal chemistry (06.05.1999)
Get full text
Journal Article
Regioselective hydroxylation of debrisoquine by cytochrome P4502D6: implications for active site modelling
Lightfoot, T., Ellis, S. W., Mahling, J., Ackland, M. J., Blaney, F. E., Bijloo, G. J., De Groot, M. J., Vermeulen, N. P. E., Blackburn, G. M., Lennard, M. S., Tucker, G. T.
Published in Xenobiotica (01.03.2000)
Published in Xenobiotica (01.03.2000)
Get full text
Journal Article
Evidence That Aspartic Acid 301 Is a Critical Substrate-Contact Residue in the Active Site of Cytochrome P450 2D6
Ellis, S W, Hayhurst, G P, Smith, G, Lightfoot, T, Wong, M M, Simula, A P, Ackland, M J, Sternberg, M J, Lennard, M S, Tucker, G T
Published in The Journal of biological chemistry (08.12.1995)
Published in The Journal of biological chemistry (08.12.1995)
Get full text
Journal Article
Metabolism of Delavirdine, a Human Immunodeficiency Virus Type-1 Reverse Transcriptase Inhibitor, by Microsomal Cytochrome P450 in Humans, Rats, and Other Species: Probable Involvement of CYP2D6 and CYP3A
VOORMAN, R. L, MAIO, S. M, HAUER, M. J, SANDERS, P. E, PAYNE, N. A, ACKLAND, M. J
Published in Drug metabolism and disposition (01.07.1998)
Get full text
Published in Drug metabolism and disposition (01.07.1998)
Journal Article
Inter-hospital comparison of mortality rates
Ansari, MZ, Ackland, MJ, Jolley, DJ, Carson, N, McDonald, IG
Published in International journal for quality in health care (01.02.1999)
Published in International journal for quality in health care (01.02.1999)
Get full text
Journal Article
Adverse events after prostatectomy in Victorian public hospitals
Ansari, M Z, Costello, A J, Jolley, D J, Ackland, M J, Carson, N, McDonald, I G
Published in ANZ journal of surgery (01.12.1998)
Published in ANZ journal of surgery (01.12.1998)
Get full text
Journal Article
PREDICTORS OF LENGTH OF STAY FOR TRANSURETHRAL PROSTATECTOMY IN VICTORIA
Ansari, M. Z., MacIntyre, C. R., Ackland, M. J., Chandraraj, E., Hailey, D.
Published in Australian and New Zealand Journal of Surgery (01.12.1998)
Published in Australian and New Zealand Journal of Surgery (01.12.1998)
Get full text
Journal Article
THE SYNTHESIS OF 5'-[C-14(1)] AND 3A, 4-[C-13(2)] LABELED PANADIPLON (U-78875 3-(5'-CYCLOPROPYL-1,2,4-OXADIAZOL-3-YL)-5-(1-METHYLETHYL)-IMIDAZO-[1,5A]-QUINOXALIN-4(5H)-ONE)
ACKLAND, MJ, HOWARD, MR, DRING, LG
Published in Journal of labelled compounds & radiopharmaceuticals (01.06.1993)
Published in Journal of labelled compounds & radiopharmaceuticals (01.06.1993)
Get more information
Journal Article
Influence of amino acid residue 374 of cytochrome P-450 2D6 (CYP2D6) on the regio- and enantio-selective metabolism of metoprolol
Ellis, S W, Rowland, K, Ackland, M J, Rekka, E, Simula, A P, Lennard, M S, Wolf, C R, Tucker, G T
Published in Biochemical journal (01.06.1996)
Published in Biochemical journal (01.06.1996)
Get full text
Journal Article
Accuracy of injury coding in Victorian hospital morbidity data
MacIntyre, C R, Ackland, M J, Chandraraj, E J
Published in Australian and New Zealand journal of public health (01.12.1997)
Get full text
Published in Australian and New Zealand journal of public health (01.12.1997)
Journal Article