53BP1 Contributes to Igh Locus Chromatin Topology during Class Switch Recombination
Feldman, Scott, Wuerffel, Robert, Achour, Ikbel, Wang, Lili, Carpenter, Phillip B, Kenter, Amy L
Published in The Journal of immunology (1950) (15.03.2017)
Published in The Journal of immunology (1950) (15.03.2017)
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Journal Article
Flexible ordering of antibody class switch and V(D)J joining during B-cell ontogeny
Kumar, Satyendra, Wuerffel, Robert, Achour, Ikbel, Lajoie, Bryan, Sen, Ranjan, Dekker, Job, Feeney, Ann J, Kenter, Amy L
Published in Genes & development (15.11.2013)
Published in Genes & development (15.11.2013)
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Journal Article
Tetrameric and Homodimeric Camelid IgGs Originate from the Same IgH Locus
Achour, Ikbel, Cavelier, Patricia, Tichit, Magali, Bouchier, Christiane, Lafaye, Pierre, Rougeon, Francois
Published in The Journal of immunology (1950) (01.08.2008)
Published in The Journal of immunology (1950) (01.08.2008)
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Journal Article
N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes
Li, Qike, Schissler, A Grant, Gardeux, Vincent, Achour, Ikbel, Kenost, Colleen, Berghout, Joanne, Li, Haiquan, Zhang, Hao Helen, Lussier, Yves A
Published in BMC medical genomics (24.05.2017)
Published in BMC medical genomics (24.05.2017)
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Journal Article
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies
Naing, Aung, Infante, Jeffrey, Goel, Sanjay, Burris, Howard, Black, Chelsea, Marshall, Shannon, Achour, Ikbel, Barbee, Susannah, May, Rena, Morehouse, Chris, Pollizzi, Kristen, Song, Xuyang, Steele, Keith, Elgeioushi, Nairouz, Walcott, Farzana, Karakunnel, Joyson, LoRusso, Patricia, Weise, Amy, Eder, Joseph, Curti, Brendan, Oberst, Michael
Published in Journal for immunotherapy of cancer (22.08.2019)
Published in Journal for immunotherapy of cancer (22.08.2019)
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Journal Article
Design and Efficacy of a Monovalent Bispecific PD-1/CTLA4 Antibody That Enhances CTLA4 Blockade on PD-1 + Activated T Cells
Dovedi, Simon J, Elder, Matthew J, Yang, Chunning, Sitnikova, Suzanne I, Irving, Lorraine, Hansen, Anna, Hair, James, Jones, Des C, Hasani, Sumati, Wang, Bo, Im, Seock-Ah, Tran, Ben, Subramaniam, Deepa S, Gainer, Shelby D, Vashisht, Kapil, Lewis, Arthur, Jin, Xiaofang, Kentner, Stacy, Mulgrew, Kathy, Wang, Yaya, Overstreet, Michael G, Dodgson, James, Wu, Yanli, Palazon, Asis, Morrow, Michelle, Rainey, Godfrey J, Browne, Gareth J, Neal, Frances, Murray, Thomas V, Toloczko, Aleksandra D, Dall'Acqua, William, Achour, Ikbel, Freeman, Daniel J, Wilkinson, Robert W, Mazor, Yariv
Published in Cancer discovery (01.05.2021)
Published in Cancer discovery (01.05.2021)
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Abstract 5667: Biomarkers associated with tertiary lymphoid structures are elevated in lung and bladder cancer patients who respond to durvalumab treatment
Sridhar, Sriram, Morehouse, Christopher M., Shreshta, Yashaswi, Rebelatto, Marlon, Achour, Ikbel, Kagiampakis, Ioannis, Oflazoglu, Ezogelin, Streicher, Katie
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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A Randomized Phase II Study of MEDI0680 in Combination with Durvalumab versus Nivolumab Monotherapy in Patients with Advanced or Metastatic Clear-cell Renal Cell Carcinoma
Voss, Martin H, Azad, Arun A, Hansen, Aaron R, Gray, Jhanelle E, Welsh, Sarah J, Song, Xuyang, Kuziora, Michael, Meinecke, Lina, Blando, Jorge, Achour, Ikbel, Wang, Yi, Walcott, Farzana L, Oosting, Sjoukje F
Published in Clinical cancer research (15.07.2022)
Published in Clinical cancer research (15.07.2022)
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Clinical and molecular features of acquired resistance to immunotherapy in non-small cell lung cancer
Memon, Danish, Schoenfeld, Adam J., Ye, Darwin, Fromm, George, Rizvi, Hira, Zhang, Xiang, Keddar, Mohamed Reda, Mathew, Divij, Yoo, Kyung Jin, Qiu, Jingya, Lihm, Jayon, Miriyala, Jayalaksmi, Sauter, Jennifer L., Luo, Jia, Chow, Andrew, Bhanot, Umesh K., McCarthy, Caroline, Vanderbilt, Chad M., Liu, Cailian, Abu-Akeel, Mohsen, Plodkowski, Andrew J., McGranahan, Nicholas, Łuksza, Marta, Greenbaum, Benjamin D., Merghoub, Taha, Achour, Ikbel, Barrett, J. Carl, Stewart, Ross, Beltrao, Pedro, Schreiber, Taylor H., Minn, Andy J., Miller, Martin L., Hellmann, Matthew D.
Published in Cancer cell (12.02.2024)
Published in Cancer cell (12.02.2024)
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Journal Article
CTLA-4 및 PD-1 이중특이적 항체를 사용한 치료 방법
GAINER SHELBY, SONG XUYANG, ACHOUR IKBEL, SUBRAMANIAM DEEPA, FREEMAN DANIEL J, FERTE CHARLES
Year of Publication 23.10.2024
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Year of Publication 23.10.2024
Patent
Safety, pharmacokinetics (PK), pharmacodynamics (PD) and preliminary efficacy of AZD2936, a bispecific antibody targeting PD-1 and TIGIT, in checkpoint inhibitor (CPI)-experienced advanced/metastatic non-small-cell lung cancer (NSCLC): First report of ARTEMIDE-01
Rohrberg, Kristoffer Staal, Brandão, Mariana, Castanon Alvarez, Eduardo, Felip, Enriqueta, Gort, Eelke Hiddo, Hiltermann, T.Jeroen Jeroen Nicolaas, Izumi, Hiroki, Kim, Dong-Wan, Kim, Sang-We, Paz-Ares, Luis G., Solomon, Benjamin J., Steinbusch, Laurie, Wauters, Els, Yoshida, Tatsuya, Chen, Huifang, Goldwin, Andrew, Jiang, Yu, Achour, Ikbel, Drachsler, Moritz Wolfgang, Cho, Byoung Chul
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
Constraints contributed by chromatin looping limit recombination targeting during Ig class switch recombination
Feldman, Scott, Achour, Ikbel, Wuerffel, Robert, Kumar, Satyendra, Gerasimova, Tatiana, Sen, Ranjan, Kenter, Amy L
Published in The Journal of immunology (1950) (01.03.2015)
Published in The Journal of immunology (1950) (01.03.2015)
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Abstract 3245: Durvalumab induces an NK cell response associated with clinical benefit of patients with advanced NSCLC
Ascierto, Maria Libera, Shrestha, Yashaswi, Zhang, Qu, Wang, Jixin, Si, Han, Greenlees, Lydia, Halpin, Rebecca, Achour, Ikbel, Cooper, Zachary Aaron, Raja, Rajiv, Abdullah, Shaad, Streicher, Katie, Higgs, Brandon
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Single-domain antibodies recognize selectively small oligomeric forms of amyloid β, prevent Aβ-induced neurotoxicity and inhibit fibril formation
Lafaye, Pierre, Achour, Ikbel, England, Patrick, Duyckaerts, Charles, Rougeon, François
Published in Molecular immunology (01.02.2009)
Published in Molecular immunology (01.02.2009)
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Journal Article
579 Novel digital image approach of multiplex immunofluorescence based PD-L1 expression enables the stratification of advanced NSCLC patients treated with durvalumab
Brieu, Nicolas, Segerer, Felix, Hessel, Harald, Gupta, Ashok, Achour, Ikbel, Schmidt, Guenter
Published in Journal for immunotherapy of cancer (01.11.2022)
Published in Journal for immunotherapy of cancer (01.11.2022)
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Journal Article
Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival
Schissler, A Grant, Gardeux, Vincent, Li, Qike, Achour, Ikbel, Li, Haiquan, Piegorsch, Walter W, Lussier, Yves A
Published in Bioinformatics (Oxford, England) (15.06.2015)
Published in Bioinformatics (Oxford, England) (15.06.2015)
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Journal Article
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform
Klarenbeek, Alex, Mazouari, Khalil El, Desmyter, Aline, Blanchetot, Christophe, Hultberg, Anna, de Jonge, Natalie, Roovers, Rob C, Cambillau, Christian, Spinelli, Sylvia, Del-Favero, Jurgen, Verrips, Theo, de Haard, Hans J, Achour, Ikbel
Published in mAbs (04.07.2015)
Published in mAbs (04.07.2015)
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Journal Article
'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine
Gardeux, Vincent, Achour, Ikbel, Li, Jianrong, Maienschein-Cline, Mark, Li, Haiquan, Pesce, Lorenzo, Parinandi, Gurunadh, Bahroos, Neil, Winn, Robert, Foster, Ian, Garcia, Joe G N, Lussier, Yves A
Published in Journal of the American Medical Informatics Association : JAMIA (01.11.2014)
Published in Journal of the American Medical Informatics Association : JAMIA (01.11.2014)
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