E-cadherin is required for metastasis in multiple models of breast cancer
Padmanaban, Veena, Krol, Ilona, Suhail, Yasir, Szczerba, Barbara M., Aceto, Nicola, Bader, Joel S., Ewald, Andrew J.
Published in Nature (London) (01.09.2019)
Published in Nature (London) (01.09.2019)
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Journal Article
Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding
Gkountela, Sofia, Castro-Giner, Francesc, Szczerba, Barbara Maria, Vetter, Marcus, Landin, Julia, Scherrer, Ramona, Krol, Ilona, Scheidmann, Manuel C., Beisel, Christian, Stirnimann, Christian U., Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Aceto, Nicola
Published in Cell (10.01.2019)
Published in Cell (10.01.2019)
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Journal Article
Circulating Tumor Cell-Neutrophil Tango along the Metastatic Process
Saini, Massimo, Szczerba, Barbara M, Aceto, Nicola
Published in Cancer research (Chicago, Ill.) (15.12.2019)
Published in Cancer research (Chicago, Ill.) (15.12.2019)
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Journal Article
Hypoxia Triggers the Intravasation of Clustered Circulating Tumor Cells
Donato, Cinzia, Kunz, Leo, Castro-Giner, Francesc, Paasinen-Sohns, Aino, Strittmatter, Karin, Szczerba, Barbara Maria, Scherrer, Ramona, Di Maggio, Nunzia, Heusermann, Wolf, Biehlmaier, Oliver, Beisel, Christian, Vetter, Marcus, Rochlitz, Christoph, Weber, Walter Paul, Banfi, Andrea, Schroeder, Timm, Aceto, Nicola
Published in Cell reports (Cambridge) (08.09.2020)
Published in Cell reports (Cambridge) (08.09.2020)
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Journal Article
Deregulation of ribosomal protein expression and translation promotes breast cancer metastasis
Ebright, Richard Y, Lee, Sooncheol, Wittner, Ben S, Niederhoffer, Kira L, Nicholson, Benjamin T, Bardia, Aditya, Truesdell, Samuel, Wiley, Devon F, Wesley, Benjamin, Li, Selena, Mai, Andy, Aceto, Nicola, Vincent-Jordan, Nicole, Szabolcs, Annamaria, Chirn, Brian, Kreuzer, Johannes, Comaills, Valentine, Kalinich, Mark, Haas, Wilhelm, Ting, David T, Toner, Mehmet, Vasudevan, Shobha, Haber, Daniel A, Maheswaran, Shyamala, Micalizzi, Douglas S
Published in Science (American Association for the Advancement of Science) (27.03.2020)
Published in Science (American Association for the Advancement of Science) (27.03.2020)
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Journal Article
Circulating Tumor Cell Clusters Are Oligoclonal Precursors of Breast Cancer Metastasis
Aceto, Nicola, Bardia, Aditya, Miyamoto, David T., Donaldson, Maria C., Wittner, Ben S., Spencer, Joel A., Yu, Min, Pely, Adam, Engstrom, Amanda, Zhu, Huili, Brannigan, Brian W., Kapur, Ravi, Stott, Shannon L., Shioda, Toshi, Ramaswamy, Sridhar, Ting, David T., Lin, Charles P., Toner, Mehmet, Haber, Daniel A., Maheswaran, Shyamala
Published in Cell (28.08.2014)
Published in Cell (28.08.2014)
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Journal Article
Cooperative interaction between ERα and the EMT-inducer ZEB1 reprograms breast cancer cells for bone metastasis
Mohammadi Ghahhari, Nastaran, Sznurkowska, Magdalena K., Hulo, Nicolas, Bernasconi, Lilia, Aceto, Nicola, Picard, Didier
Published in Nature communications (19.04.2022)
Published in Nature communications (19.04.2022)
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High blood flow shear stress values are associated with circulating tumor cells cluster disaggregation in a multi-channel microfluidic device
Marrella, Alessandra, Fedi, Arianna, Varani, Gabriele, Vaccari, Ivan, Fato, Marco, Firpo, Giuseppe, Guida, Patrizia, Aceto, Nicola, Scaglione, Silvia
Published in PloS one (14.01.2021)
Published in PloS one (14.01.2021)
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Journal Article
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
Yu, Min, Bardia, Aditya, Aceto, Nicola, Bersani, Francesca, Madden, Marissa W., Donaldson, Maria C., Desai, Rushil, Zhu, Huili, Comaills, Valentine, Zheng, Zongli, Wittner, Ben S., Stojanov, Petar, Brachtel, Elena, Sgroi, Dennis, Kapur, Ravi, Shioda, Toshihiro, Ting, David T., Ramaswamy, Sridhar, Getz, Gad, Iafrate, A. John, Benes, Cyril, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A.
Published in Science (American Association for the Advancement of Science) (11.07.2014)
Published in Science (American Association for the Advancement of Science) (11.07.2014)
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Journal Article
En Route to Metastasis: Circulating Tumor Cell Clusters and Epithelial-to-Mesenchymal Transition
Aceto, Nicola, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel A
Published in Trends in cancer (01.09.2015)
Published in Trends in cancer (01.09.2015)
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Journal Article
Cell-free DNA analysis in healthy individuals by next-generation sequencing: a proof of concept and technical validation study
Alborelli, Ilaria, Generali, Daniele, Jermann, Philip, Cappelletti, Maria Rosa, Ferrero, Giuseppina, Scaggiante, Bruna, Bortul, Marina, Zanconati, Fabrizio, Nicolet, Stefan, Haegele, Jasmin, Bubendorf, Lukas, Aceto, Nicola, Scaltriti, Maurizio, Mucci, Giuseppe, Quagliata, Luca, Novelli, Giuseppe
Published in Cell death & disease (11.07.2019)
Published in Cell death & disease (11.07.2019)
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Journal Article
Microfluidic isolation of platelet-covered circulating tumor cells
Jiang, Xiaocheng, Wong, Keith H. K, Khankhel, Aimal H, Zeinali, Mahnaz, Reategui, Eduardo, Phillips, Matthew J, Luo, Xi, Aceto, Nicola, Fachin, Fabio, Hoang, Anh N, Kim, Wooseok, Jensen, Annie E, Sequist, Lecia V, Maheswaran, Shyamala, Haber, Daniel A, Stott, Shannon L, Toner, Mehmet
Published in Lab on a chip (11.10.2017)
Published in Lab on a chip (11.10.2017)
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Journal Article
Tyrosine phosphatase SHP2 promotes breast cancer progression and maintains tumor-initiating cells via activation of key transcription factors and a positive feedback signaling loop
Aceto, Nicola, Sausgruber, Nina, Brinkhaus, Heike, Gaidatzis, Dimos, Martiny-Baron, Georg, Mazzarol, Giovanni, Confalonieri, Stefano, Quarto, Micaela, Hu, Guang, Balwierz, Piotr J, Pachkov, Mikhail, Elledge, Stephen J, van Nimwegen, Erik, Stadler, Michael B, Bentires-Alj, Mohamed
Published in Nature medicine (01.04.2012)
Published in Nature medicine (01.04.2012)
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Expression of β-globin by cancer cells promotes cell survival during blood-borne dissemination
Zheng, Yu, Miyamoto, David T., Wittner, Ben S., Sullivan, James P., Aceto, Nicola, Jordan, Nicole Vincent, Yu, Min, Karabacak, Nezihi Murat, Comaills, Valentine, Morris, Robert, Desai, Rushil, Desai, Niyati, Emmons, Erin, Milner, John D., Lee, Richard J., Wu, Chin-Lee, Sequist, Lecia V., Haas, Wilhelm, Ting, David T., Toner, Mehmet, Ramaswamy, Sridhar, Maheswaran, Shyamala, Haber, Daniel A.
Published in Nature communications (09.02.2017)
Published in Nature communications (09.02.2017)
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Journal Article
Genomic Instability Is Induced by Persistent Proliferation of Cells Undergoing Epithelial-to-Mesenchymal Transition
Comaills, Valentine, Kabeche, Lilian, Morris, Robert, Buisson, Rémi, Yu, Min, Madden, Marissa Wells, LiCausi, Joseph A., Boukhali, Myriam, Tajima, Ken, Pan, Shiwei, Aceto, Nicola, Sil, Srinjoy, Zheng, Yu, Sundaresan, Tilak, Yae, Toshifumi, Jordan, Nicole Vincent, Miyamoto, David T., Ting, David T., Ramaswamy, Sridhar, Haas, Wilhelm, Zou, Lee, Haber, Daniel A., Maheswaran, Shyamala
Published in Cell reports (Cambridge) (06.12.2016)
Published in Cell reports (Cambridge) (06.12.2016)
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