Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (03.09.2019)
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Journal Article
PRMT5 and CDK4/6 inhibition result in distinctive patterns of alternative splicing in melanoma
Chan, Lok Hang, Wang, Peihan, Abuhammad, Shatha, Lim, Lydia Rui Jia, Cursons, Joseph, Sheppard, Karen E, Goode, David L
Published in PloS one (02.11.2023)
Published in PloS one (02.11.2023)
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A novel immunogenic mouse model of melanoma for the preclinical assessment of combination targeted and immune-based therapy
Lelliott, Emily J., Cullinane, Carleen, Martin, Claire A., Walker, Rachael, Ramsbottom, Kelly M., Souza-Fonseca-Guimaraes, Fernando, Abuhammad, Shatha, Michie, Jessica, Kirby, Laura, Young, Richard J., Slater, Alison, Lau, Peter, Meeth, Katrina, Oliaro, Jane, Haynes, Nicole, McArthur, Grant A., Sheppard, Karen E.
Published in Scientific reports (04.02.2019)
Published in Scientific reports (04.02.2019)
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Abstract A061: Targeting PRMT5 enhances the response to CDK4/6 inhibitors in multiple cancer types
AbuHammad, Shatha, McArthur, Grant A, Sheppard, Karen
Published in Molecular cancer therapeutics (01.12.2019)
Published in Molecular cancer therapeutics (01.12.2019)
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Journal Article
Palbociclib synergizes with BRAF and MEK inhibitors in treatment naïve melanoma but not after the development of BRAF inhibitor resistance
Martin, Claire A., Cullinane, Carleen, Kirby, Laura, Abuhammad, Shatha, Lelliott, Emily J., Waldeck, Kelly, Young, Richard J., Brajanovski, Natalie, Cameron, Donald P., Walker, Rachael, Sanij, Elaine, Poortinga, Gretchen, Hannan, Ross D., Pearson, Richard B., Hicks, Rodney J., McArthur, Grant A., Sheppard, Karen E.
Published in International journal of cancer (15.05.2018)
Published in International journal of cancer (15.05.2018)
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Journal Article
Integrative clinical and molecular characterization of translocation renal cell carcinoma
Bakouny, Ziad, Sadagopan, Ananthan, Ravi, Praful, Metaferia, Nebiyou Y, Li, Jiao, AbuHammad, Shatha, Tang, Stephen, Denize, Thomas, Garner, Emma R, Gao, Xin, Braun, David A, Hirsch, Laure, Steinharter, John A, Bouchard, Gabrielle, Walton, Emily, West, Destiny, Labaki, Chris, Dudani, Shaan, Gan, Chun-Loo, Sethunath, Vidyalakshmi, Carvalho, Filipe L F, Imamovic, Alma, Ricker, Cora, Vokes, Natalie I, Nyman, Jackson, Berchuck, Jacob E, Park, Jihye, Hirsch, Michelle S, Haq, Rizwan, Mary Lee, Gwo-Shu, McGregor, Bradley A, Chang, Steven L, Feldman, Adam S, Wu, Catherine J, McDermott, David F, Heng, Daniel Y C, Signoretti, Sabina, Van Allen, Eliezer M, Choueiri, Toni K, Viswanathan, Srinivas R
Published in Cell reports (Cambridge) (04.01.2022)
Published in Cell reports (Cambridge) (04.01.2022)
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A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
Tang, Stephen, Sethunath, Vidyalakshmi, Metaferia, Nebiyou Y., Nogueira, Marina F., Gallant, Daniel S., Garner, Emma R., Lairson, Lauren A., Penney, Christopher M., Li, Jiao, Gelbard, Maya K., Alaiwi, Sarah Abou, Seo, Ji-Heui, Hwang, Justin H., Strathdee, Craig A., Baca, Sylvan C., AbuHammad, Shatha, Zhang, Xiaoyang, Doench, John G., Hahn, William C., Takeda, David Y., Freedman, Matthew L., Choi, Peter S., Viswanathan, Srinivas R.
Published in Cell reports (Cambridge) (22.02.2022)
Published in Cell reports (Cambridge) (22.02.2022)
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Journal Article
PRMT5 and CDK4/6 inhibition result in distinctive patterns of alternative splicing in melanoma
Lok Hang Chan, Peihan Wang, Shatha Abuhammad, Lydia Rui Jia Lim, Joseph Cursons, Karen E Sheppard, David L Goode
Published in PloS one (01.01.2023)
Published in PloS one (01.01.2023)
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Journal Article
Correction: Regulation of PRMT5–MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma
AbuHammad, Shatha, Cullinane, Carleen, Martin, Claire, Bacolas, Zoe, Ward, Teresa, Chen, Huiqin, Slater, Alison, Ardley, Kerry, Kirby, Laura, Chan, Keefe T., Brajanovski, Natalie, Smith, Lorey K., Rao, Aparna D., Lelliott, Emily J., Kleinschmidt, Margarete, Vergara, Ismael A., Papenfuss, Anthony T., Lau, Peter, Ghosh, Prerana, Haupt, Sue, Haupt, Ygal, Sanij, Elaine, Poortinga, Gretchen, Pearson, Richard B., Falk, Hendrik, Curtis, David J., Stupple, Paul, Devlin, Mark, Street, Ian, Davies, Michael A., McArthur, Grant A., Sheppard, Karen E.
Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2020)
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Published in Proceedings of the National Academy of Sciences - PNAS (28.04.2020)
Journal Article
Inhibitory Effects of New Mercapto Xanthine Derivatives in Human mcf7 and k562 Cancer Cell Lines
Sultani, Haider N., Ghazal, Rasha A., Hayallah, Alaa M., Abdulrahman, Loay K., Abu‐Hammour, Khaled, AbuHammad, Shatha, Taha, Mutasem O., Zihlif, Malek A.
Published in Journal of heterocyclic chemistry (01.01.2017)
Published in Journal of heterocyclic chemistry (01.01.2017)
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Journal Article
A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer
Tang, Stephen, Metaferia, Nebiyou Y, Nogueira, Marina F, Gelbard, Maya K, Sarah Abou Alaiwi, Ji-Heui Seo, Hwang, Justin H, Strathdee, Craig A, Baca, Sylvan C, Jiao, Li, Abuhammad, Shatha, Zhang, Xiaoyang, Doench, John G, Hahn, William C, Takeda, David Y, Freedman, Matthew L, Choi, Peter S, Viswanathan, Srinivas R
Published in bioRxiv (09.07.2020)
Published in bioRxiv (09.07.2020)
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Paper
Integrative Clinical and Molecular Characterization of Translocation Renal Cell Carcinoma
Bakouny, Ziad, Sadagopan, Ananthan, Ravi, Praful, Metaferia, Nebiyou Y, Jiao, Li, Abuhammad, Shatha, Tang, Stephen, Denize, Thomas, Garner, Emma R, Gao, Xin, Braun, David A, Hirsch, Laure, Steinharter, John A, Bouchard, Gabrielle, Walton, Emily, West, Destiny, Labaki, Chris, Dudani, Shaan, Chun-Loo Gan, Sethunath, Vidyalakshmi, Carvalho, Filipe Lf, Imamovic, Alma, Ricker, Cora, Vokes, Natalie I, Nyman, Jackson, Park, Jihye, Hirsch, Michelle S, Haq, Rizwan, Gwo-Shu, Mary Lee, Mcgregor, Bradley A, Chang, Steven L, Feldman, Adam S, Wu, Catherine J, Mcdermott, David F, Heng, Daniel Yc, Signoretti, Sabina, Van Allen, Eliezer M, Choueiri, Toni K, Viswanathan, Srinivas R
Published in bioRxiv (15.04.2021)
Published in bioRxiv (15.04.2021)
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