Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease
Dong, Bingning, Saha, Pradip K, Huang, Wendong, Chen, Wenling, Abu-Elheiga, Lutfi A, Wakil, Salih J, Stevens, Robert D, Ilkayeva, Olga, Newgard, Christopher B, Chan, Lawrence, Moore, David D
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (03.11.2009)
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Acetyl-CoA Carboxylase 2−/− Mutant Mice are Protected against Fatty Liver under High-fat, High-carbohydrate Dietary and de Novo Lipogenic Conditions
Abu-Elheiga, Lutfi, Wu, Hongmei, Gu, Ziwei, Bressler, Rubin, Wakil, Salih J.
Published in The Journal of biological chemistry (06.04.2012)
Published in The Journal of biological chemistry (06.04.2012)
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Identification and Quantitation of Malonic Acid Biomarkers of In-Born Error Metabolism by Targeted Metabolomics
Ambati, Chandra Shekar R., Yuan, Furong, Abu-Elheiga, Lutfi A., Zhang, Yiqing, Shetty, Vivekananda
Published in Journal of the American Society for Mass Spectrometry (01.05.2017)
Published in Journal of the American Society for Mass Spectrometry (01.05.2017)
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Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T Cells in Chronic Infection
Ibitokou, Samad A, Dillon, Brian E, Sinha, Mala, Szczesny, Bartosz, Delgadillo, Añahi, Reda Abdelrahman, Doaa, Szabo, Csaba, Abu-Elheiga, Lutfi, Porter, Craig, Tuvdendorj, Demidmaa, Stephens, Robin
Published in The Journal of immunology (1950) (15.01.2018)
Published in The Journal of immunology (1950) (15.01.2018)
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Journal Article
Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity
Choi, Cheol Soo, Savage, David B, Abu-Elheiga, Lutfi, Liu, Zhen-Xiang, Kim, Sheene, Kulkarni, Ameya, Distefano, Alberto, Hwang, Yu-Jin, Reznick, Richard M, Codella, Roberto, Zhang, Dongyan, Cline, Gary W, Wakil, Salih J, Shulman, Gerald I
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (16.10.2007)
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Acetyl-CoA Carboxylase 2 Mutant Mice Are Protected against Obesity and Diabetes Induced by High-Fat/High-Carbohydrate Diets
Abu-Elheiga, Lutfi, Oh, Wonkeun, Kordari, Parichher, Wakil, Salih J.
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.2003)
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Journal Article
Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis
Mao, J, DeMayo, F.J, Li, H, Abu-Elheiga, L, Gu, Z, Shaikenov, T.E, Kordari, P, Chirala, S.S, Heird, W.C, Wakil, S.J
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (30.05.2006)
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Journal Article
Fatty Acid Synthesis Is Essential in Embryonic Development: Fatty Acid Synthase Null Mutants and Most of the Heterozygotes Die in utero
Chirala, Subrahmanyam S., Chang, Hua, Matzuk, Martin, Abu-Elheiga, Lutfi, Mao, Jianqiang, Mahon, Kathleen, Finegold, Milton, Wakil, Salih J.
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (27.05.2003)
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Journal Article
Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice
Oh, W, Abu-Elheiga, L, Kordari, P, Gu, T, Shaikenov, T, Chirala, S.S, Wakil, S.J
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2005)
Published in Proceedings of the National Academy of Sciences - PNAS (01.02.2005)
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Journal Article
Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule
Jung, Dongju, Abu-Elheiga, Lutfi, Ayuzawa, Rie, Gu, Ziwei, Shirakawa, Takashi, Fujiki, Yukio, Nakatsuji, Norio, Wakil, Salih J, Uesugi, Motonari
Published in Biochemical journal (15.12.2012)
Published in Biochemical journal (15.12.2012)
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Journal Article
Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice
Essop, M. Faadiel, Camp, Heidi S, Choi, Cheol Soo, Sharma, Saumya, Fryer, Ryan M, Reinhart, Glenn A, Guthrie, Patrick H, Bentebibel, Assia, Gu, Zeiwei, Shulman, Gerald I, Taegtmeyer, Heinrich, Wakil, Salih J, Abu-Elheiga, Lutfi
Published in American journal of physiology. Heart and circulatory physiology (01.07.2008)
Published in American journal of physiology. Heart and circulatory physiology (01.07.2008)
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Journal Article
Early Inhibition of Fatty Acid Synthesis Reduces Generation of Memory Precursor Effector T cells in Chronic Infection
Ibitokou, Samad, Dillon, Brian E., Sinha, Mala, Szczesny, Bartosz, Delgadillo, Añahi, Abdelrahman, Doaa Reda, Szabo, Csaba, Abu-Elheiga, Lutfi, Porter, Craig, Tuvdendorj, Demidmaa, Stephens, Robin
Published in The Journal of immunology (1950) (01.05.2018)
Published in The Journal of immunology (1950) (01.05.2018)
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Journal Article
Reply to Hoehn et al.: Phenotypic Discrepancies in Acetyl-CoA Carboxylase 2-deficient Mice
Abu-Elheiga, Lutfi, Wu, Hongmei, Gu, Ziwei, Wakil, Salih J.
Published in The Journal of biological chemistry (04.05.2012)
Published in The Journal of biological chemistry (04.05.2012)
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Journal Article
Human Acetyl-CoA Carboxylase 2
Abu-Elheiga, Lutfi, Almarza-Ortega, Deysee B., Baldini, Antonio, Wakil, Salih J.
Published in The Journal of biological chemistry (18.04.1997)
Published in The Journal of biological chemistry (18.04.1997)
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Journal Article
Synthesis and Evaluation of Diarylthiazole Derivatives That Inhibit Activation of Sterol Regulatory Element-Binding Proteins
Kamisuki, Shinji, Shirakawa, Takashi, Kugimiya, Akira, Abu-Elheiga, Lutfi, Park Choo, Hea-Young, Yamada, Kohei, Shimogawa, Hiroki, Wakil, Salih J, Uesugi, Motonari
Published in Journal of medicinal chemistry (14.07.2011)
Published in Journal of medicinal chemistry (14.07.2011)
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Journal Article
Isolation and Chromosomal Mapping of Genomic Clones Encoding the Human Fatty Acid Synthase Gene
Jayakumar, Arumugam, Chirala, Subrahmanyam S., Chinault, A.Craig, Baldini, Antonio, Abu-Elheiga, Lutfi, Wakil, Salih J.
Published in Genomics (San Diego, Calif.) (15.09.1994)
Published in Genomics (San Diego, Calif.) (15.09.1994)
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