Immunomodulatory Effects of Lenvatinib Plus Anti–Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma
Torrens, Laura, Montironi, Carla, Puigvehí, Marc, Mesropian, Agavni, Leslie, Jack, Haber, Philipp K., Maeda, Miho, Balaseviciute, Ugne, Willoughby, Catherine E., Abril‐Fornaguera, Jordi, Piqué‐Gili, Marta, Torres‐Martín, Miguel, Peix, Judit, Geh, Daniel, Ramon‐Gil, Erik, Saberi, Behnam, Friedman, Scott L., Mann, Derek A., Sia, Daniela, Llovet, Josep M.
Published in Hepatology (Baltimore, Md.) (01.11.2021)
Published in Hepatology (Baltimore, Md.) (01.11.2021)
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Journal Article
Liver Injury Increases the Incidence of HCC following AAV Gene Therapy in Mice
Dalwadi, Dhwanil A., Torrens, Laura, Abril-Fornaguera, Jordi, Pinyol, Roser, Willoughby, Catherine, Posey, Jeffrey, Llovet, Josep M., Lanciault, Christian, Russell, David W., Grompe, Markus, Naugler, Willscott E.
Published in Molecular therapy (03.02.2021)
Published in Molecular therapy (03.02.2021)
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Metabolic Landscape of the Mouse Liver by Quantitative 31P Nuclear Magnetic Resonance Analysis of the Phosphorome
Bernardo‐Seisdedos, Ganeko, Bilbao, Jon, Fernández‐Ramos, David, Lopitz‐Otsoa, Fernando, Gutierrez de Juan, Virginia, Bizkarguenaga, Maider, Mateos, Borja, Fondevila, Marcos F., Abril‐Fornaguera, Jordi, Diercks, Tammo, Lu, Shelly C., Nogueiras, Rubén, Mato, José M., Millet, Oscar
Published in Hepatology (Baltimore, Md.) (01.07.2021)
Published in Hepatology (Baltimore, Md.) (01.07.2021)
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Journal Article
Oncogenic role of PMEPA1 and its association with immune exhaustion and TGF-β activation in HCC
Piqué-Gili, Marta, Andreu-Oller, Carmen, Mesropian, Agavni, Esteban-Fabró, Roger, Bárcena-Varela, Marina, Ruiz de Galarreta, Marina, Montironi, Carla, Martinez-Quetglas, Iris, Cappuyns, Sarah, Peix, Judit, Keraite, Ieva, Gris-Oliver, Albert, Fernández-Martínez, Elisa, Mauro, Ezequiel, Torres-Martin, Miguel, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Lambrechts, Diether, Dekervel, Jeroen, Thung, Swan N., Sia, Daniela, Lujambio, Amaia, Pinyol, Roser, Llovet, Josep M.
Published in JHEP reports (01.11.2024)
Published in JHEP reports (01.11.2024)
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Journal Article
Cabozantinib Enhances Anti-PD1 Activity and Elicits a Neutrophil-Based Immune Response in Hepatocellular Carcinoma
Esteban-Fabró, Roger, Willoughby, Catherine E, Piqué-Gili, Marta, Montironi, Carla, Abril-Fornaguera, Jordi, Peix, Judit, Torrens, Laura, Mesropian, Agavni, Balaseviciute, Ugne, Miró-Mur, Francesc, Mazzaferro, Vincenzo, Pinyol, Roser, Llovet, Josep M
Published in Clinical cancer research (01.06.2022)
Published in Clinical cancer research (01.06.2022)
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Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications
Carrillo-Reixach, Juan, Torrens, Laura, Simon-Coma, Marina, Royo, Laura, Domingo-Sàbat, Montserrat, Abril-Fornaguera, Jordi, Akers, Nicholas, Sala, Margarita, Ragull, Sonia, Arnal, Magdalena, Villalmanzo, Núria, Cairo, Stefano, Villanueva, Alberto, Kappler, Roland, Garrido, Marta, Guerra, Laura, Sábado, Constantino, Guillén, Gabriela, Mallo, Mar, Piñeyro, David, Vázquez-Vitali, María, Kuchuk, Olga, Mateos, María Elena, Ramírez, Gema, Santamaría, Manuel López, Mozo, Yasmina, Soriano, Aroa, Grotzer, Michael, Branchereau, Sophie, de Andoin, Nagore García, López-Ibor, Blanca, López-Almaraz, Ricardo, Salinas, José Antonio, Torres, Bárbara, Hernández, Francisco, Uriz, José Javier, Fabre, Monique, Blanco, Julià, Paris, Claudia, Bajčiová, Viera, Laureys, Geneviève, Masnou, Helena, Clos, Ariadna, Belendez, Cristina, Guettier, Catherine, Sumoy, Lauro, Planas, Ramón, Jordà, Mireia, Nonell, Lara, Czauderna, Piotr, Morland, Bruce, Sia, Daniela, Losic, Bojan, Buendia, Marie Annick, Sarrias, Maria Rosa, Llovet, Josep M., Armengol, Carolina
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
FRI-467 Efficacy of WNTinib, a novel selective therapeutic for CTNNB1 mutant tumors, in preclinical models of hepatoblastoma
Balaseviciute, Ugne, Abril-Fornaguera, Jordi, Huguet-Pradell, Júlia, Rialdi, Alex, Fernández-Martínez, Elisa, Gris-Oliver, Albert, Mesropian, Agavni, Ulukaya, Gulay, Hasson, Dan, Keraite, Ieva, Pinyol, Roser, Thung, Swan N., Guccione, Ernesto, Llovet, Josep
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Journal Article
Predicting response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma using single-cell RNA-sequencing-derived gene signatures
Cappuyns, Sarah, Piqué-Gili, Marta, Esteban-Fabró, Roger, Philips, Gino, Pinyol, Roser, Vandecaveye, Vincent, Abril-Fornaguera, Jordi, Haber, Philipp, Verslype, Chris, Van Cutsem, Eric, Lambrechts, Diether, Villanueva, Augusto, Dekervel, Jeroen, Llovet, Josep
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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Journal Article
OS-059-YI - Predicting response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma using single-cell RNA-sequencing-derived gene signatures
Cappuyns, Sarah, Piqué-Gili, Marta, Esteban-Fabró, Roger, Philips, Gino, Pinyol, Roser, Vandecaveye, Vincent, Abril-Fornaguera, Jordi, Haber, Philipp, Verslype, Chris, Van Cutsem, Eric, Lambrechts, Diether, Villanueva, Augusto, Dekervel, Jeroen, Llovet, Josep
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
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Journal Article
TOP-507-YI Single-cell RNA sequencing-derived gene signatures reveal distinct response mechanisms to atezolizumab + bevacizumab in advanced hepatocellular carcinoma
Cappuyns, Sarah, Piqué-Gili, Marta, Esteban-Fabró, Roger, Philips, Gino, Pinyol, Roser, Gris-Oliver, Albert, Vandecaveye, Vincent, Abril-Fornaguera, Jordi, Montironi, Carla, Bassaganyas, Laia, Peix, Judit, Zeitlhoefler, Marcus, Mesropian, Agavni, Huguet-Pradell, Júlia, Haber, Philipp, Mohr, Raphael, Meyer, Tim, Reeves, Helen Louise, Edeline, Julien, Finkelmeier, Fabian, Trojan, Jörg, Galle, Peter R., Foerster, Friedrich, Minguez, Beatriz, Montal, Robert, Heikenwälder, Mathias, Verslype, Chris, Van Cutsem, Eric, Lambrechts, Diether, Villanueva, Augusto, Dekervel, Jeroen, Llovet, Josep
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
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Journal Article
Cabozantinib enhances the efficacy and immune modulatory activity of anti-PD1 therapy in a syngeneic mouse model of hepatocellular carcinoma
Esteban-Fabró, Roger, Willoughby, Catherine E., Piqué-Gili, Marta, Peix, Judit, Montironi, Carla, Abril-Fornaguera, Jordi, Torrens, Laura, Pinyol, Roser, Llovet, Josep M.
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
AS053 - Cabozantinib enhances the efficacy and immune modulatory activity of anti-PD1 therapy in a syngeneic mouse model of hepatocellular carcinoma
Esteban-Fabró, Roger, Willoughby, Catherine E., Piqué-Gili, Marta, Peix, Judit, Montironi, Carla, Abril-Fornaguera, Jordi, Torrens, Laura, Pinyol, Roser, Llovet, Josep M.
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
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Journal Article
Identification of IGF2 as Genomic Driver and Actionable Therapeutic Target in Hepatoblastoma
Abril-Fornaguera, Jordi, Torrens, Laura, Andreu-Oller, Carmen, Carrillo-Reixach, Juan, Rialdi, Alex, Balaseviciute, Ugne, Pinyol, Roser, Montironi, Carla, Haber, Philipp K, Del Río-Álvarez, Álvaro, Domingo-Sàbat, Montserrat, Royo, Laura, Akers, Nicholas K, Willoughby, Catherine E, Peix, Judit, Torres-Martin, Miguel, Puigvehi, Marc, Cairo, Stefano, Childs, Margaret, Maibach, Rudolf, Alaggio, Rita, Czauderna, Piotr, Morland, Bruce, Losic, Bojan, Mazzaferro, Vincenzo, Guccione, Ernesto, Sia, Daniela, Armengol, Carolina, Llovet, Josep M
Published in Molecular cancer therapeutics (03.04.2023)
Published in Molecular cancer therapeutics (03.04.2023)
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Journal Article
WNTinib is a multi-kinase inhibitor with specificity against β-catenin mutant hepatocellular carcinoma
Rialdi, Alex, Duffy, Mary, Scopton, Alex P, Fonseca, Frank, Zhao, Julia Nanyi, Schwarz, Megan, Molina-Sanchez, Pedro, Mzoughi, Slim, Arceci, Elisa, Abril-Fornaguera, Jordi, Meadows, Austin, Ruiz de Galarreta, Marina, Torre, Denis, Reyes, Kyna, Lim, Yan Ting, Rosemann, Felix, Khan, Zaigham M, Mohammed, Kevin, Wang, Xuedi, Yu, Xufen, Lakshmanan, Manikandan, Rajarethinam, Ravisankar, Tan, Soo Yong, Jin, Jian, Villanueva, Augusto, Michailidis, Eleftherios, De Jong, Ype P, Rice, Charles M, Marazzi, Ivan, Hasson, Dan, Llovet, Josep M, Sobota, Radoslaw M, Lujambio, Amaia, Guccione, Ernesto, Dar, Arvin C
Published in Nature cancer (01.08.2023)
Published in Nature cancer (01.08.2023)
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Abstract PR02: PMEPA1 has an oncogenic role in the context of TGF-β signaling in hepatocellular carcinoma
Piqué-Gili, Marta, Andreu-Oller, Carmen, Pinyol, Roser, Esteban, Roger, Bárcena-Varela, Marina, Peix, Judit, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Torres-Martin, Miguel, Huguet-Pradell, Júlia, Sia, Daniela, Lujambio, Amaia, Llovet, Josep M
Published in Clinical cancer research (01.09.2022)
Published in Clinical cancer research (01.09.2022)
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Journal Article
Abstract 840: PMEPA1 is an oncogene linked to TGF-β signaling in hepatocellular carcinoma
Piqué-Gili, Marta, Andreu-Oller, Carmen, Pinyol, Roser, Bárcena-Varela, Marina, Esteban-Fabró, Roger, Peix, Judit, Abril-Fornaguera, Jordi, Lindblad, Katherine E., Torres-Martin, Miguel, Sia, Daniela, Lujambio, Amaia, Llovet, Josep M.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
Abstract PO009: Identification of IGF2 as genomic driver and actionable therapeutic target in hepatoblastoma
Abril-Fornaguera, Jordi, Torrens, Laura, Carrillo-Reixach, Juan, Rialdi, Alex, Balaseviciute, Ugne, Huguet-Pradell, Júlia, Montironi, Carla, Haber, Philipp, Del Río-Álvarez, Álvaro, Domingo-Sàbat, Montserrat, Royo, Laura, Akers, Nicholas, Willoughby, Catherine E, Peix, Judit, Torres-Martin, Miguel, Puigvehi, Marc, Pinyol, Roser, Cairo, Stefano, Childs, Margaret, Maibach, Rudolf, Alaggio, Rita, Czauderna, Piotr, Morland, Bruce, Losic, Bojan, Mazzaferro, Vincenzo, Guccione, Ernesto, Sia, Daniela, Armengol, Carolina, Llovet, Josep M
Published in Clinical cancer research (01.09.2022)
Published in Clinical cancer research (01.09.2022)
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Journal Article
Metabolic Landscape of the Mouse Liver by Quantitative 31 P Nuclear Magnetic Resonance Analysis of the Phosphorome
Bernardo-Seisdedos, Ganeko, Bilbao, Jon, Fernández-Ramos, David, Lopitz-Otsoa, Fernando, Gutierrez de Juan, Virginia, Bizkarguenaga, Maider, Mateos, Borja, Fondevila, Marcos F, Abril-Fornaguera, Jordi, Diercks, Tammo, Lu, Shelly C, Nogueiras, Rubén, Mato, José M, Millet, Oscar
Published in Hepatology (Baltimore, Md.) (01.07.2021)
Published in Hepatology (Baltimore, Md.) (01.07.2021)
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Journal Article
Abstract 4005: Identification of IGF2 as genomic driver and actionable therapeutic target in hepatoblastoma
Abril-Fornaguera, Jordi, Torrens, Laura, Carrillo-Reixach, Juan, Rialdi, Alexander, Balaseviciute, Ugne, Montironi, Carla, Haber, Philipp, Río-Álvarez, Álvaro Del, Domingo-Sàbat, Montserrat, Royo, Laura, Akers, Nicholas, Willoughby, Catherine E., Peix, Judit, Torres-Martin, Miguel, Puigvehi, Marc, Pinyol, Roser, Cairo, Stefano, Childs, Margaret, Maibach, Rudolf, Alaggio, Rita, Czauderna, Piotr, Morland, Bruce, Losic, Bojan, Mazzaferro, Vincenzo, Guccione, Ernesto, Sia, Daniela, Armengol, Carolina, Llovet, Josep M.
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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