Notch promotes recurrence of dormant tumor cells following HER2/neu-targeted therapy
Abravanel, Daniel L, Belka, George K, Pan, Tien-chi, Pant, Dhruv K, Collins, Meredith A, Sterner, Christopher J, Chodosh, Lewis A
Published in The Journal of clinical investigation (01.06.2015)
Published in The Journal of clinical investigation (01.06.2015)
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Exemestane plus everolimus and palbociclib in metastatic breast cancer: clinical response and genomic/transcriptomic determinants of resistance in a phase I/II trial
Gómez Tejeda Zañudo, Jorge, Barroso-Sousa, Romualdo, Jain, Esha, Jin, Qingchun, Li, Tianyu, Buendia-Buendia, Jorge E., Pereslete, Alyssa, Abravanel, Daniel L., Ferreira, Arlindo R., Wrabel, Eileen, Helvie, Karla, Hughes, Melissa E., Partridge, Ann H., Overmoyer, Beth, Lin, Nancy U., Tayob, Nabihah, Tolaney, Sara M., Wagle, Nikhil
Published in Nature communications (19.03.2024)
Published in Nature communications (19.03.2024)
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A multi-modal single-cell and spatial expression map of metastatic breast cancer biopsies across clinicopathological features
Klughammer, Johanna, Abravanel, Daniel L, Segerstolpe, Åsa, Blosser, Timothy R, Goltsev, Yury, Cui, Yi, Goodwin, Daniel R, Sinha, Anubhav, Ashenberg, Orr, Slyper, Michal, Vigneau, Sébastien, Jané-Valbuena, Judit, Alon, Shahar, Caraccio, Chiara, Chen, Judy, Cohen, Ofir, Cullen, Nicole, DelloStritto, Laura K, Dionne, Danielle, Files, Janet, Frangieh, Allison, Helvie, Karla, Hughes, Melissa E, Inga, Stephanie, Kanodia, Abhay, Lako, Ana, MacKichan, Colin, Mages, Simon, Moriel, Noa, Murray, Evan, Napolitano, Sara, Nguyen, Kyleen, Nitzan, Mor, Ortiz, Rebecca, Patel, Miraj, Pfaff, Kathleen L, Porter, Caroline B M, Rotem, Asaf, Strauss, Sarah, Strasser, Robert, Thorner, Aaron R, Turner, Madison, Wakiro, Isaac, Waldman, Julia, Wu, Jingyi, Gómez Tejeda Zañudo, Jorge, Zhang, Diane, Lin, Nancy U, Tolaney, Sara M, Winer, Eric P, Boyden, Edward S, Chen, Fei, Nolan, Garry P, Rodig, Scott J, Zhuang, Xiaowei, Rozenblatt-Rosen, Orit, Johnson, Bruce E, Regev, Aviv, Wagle, Nikhil
Published in Nature medicine (30.10.2024)
Published in Nature medicine (30.10.2024)
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Expansion sequencing: Spatially precise in situ transcriptomics in intact biological systems
Alon, Shahar, Goodwin, Daniel R, Sinha, Anubhav, Wassie, Asmamaw T, Chen, Fei, Daugharthy, Evan R, Bando, Yosuke, Kajita, Atsushi, Xue, Andrew G, Marrett, Karl, Prior, Robert, Cui, Yi, Payne, Andrew C, Yao, Chun-Chen, Suk, Ho-Jun, Wang, Ru, Yu, Chih-Chieh Jay, Tillberg, Paul, Reginato, Paul, Pak, Nikita, Liu, Songlei, Punthambaker, Sukanya, Iyer, Eswar P R, Kohman, Richie E, Miller, Jeremy A, Lein, Ed S, Lako, Ana, Cullen, Nicole, Rodig, Scott, Helvie, Karla, Abravanel, Daniel L, Wagle, Nikhil, Johnson, Bruce E, Klughammer, Johanna, Slyper, Michal, Waldman, Julia, Jané-Valbuena, Judit, Rozenblatt-Rosen, Orit, Regev, Aviv, Church, George M, Marblestone, Adam H, Boyden, Edward S
Published in Science (American Association for the Advancement of Science) (29.01.2021)
Published in Science (American Association for the Advancement of Science) (29.01.2021)
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Abstract P4-01-06: Genomic and transcriptomic analysis reveals known and novel resistance mechanisms to CDK4/6 inhibitors and sensitivity factors for the response to triplet therapy (palbociclib + everolimus + exemestane) in a phase I/IIb study in hormone-receptor positive (HR+)/HER2- metastatic breast cancer (MBC) after progression on a CDK4/6 inhibitor (CDK4/6i)
Zanudo, Jorge Gomez Tejeda, Barroso-Sousa, Romualdo, Jain, Esha, Buendia-Buendia, Jorge, Li, Tianyu, Tayob, Nabihah, Rees, Rebecca, Pereslete, Alyssa, Ferreira, Arlindo R., Abravanel, Daniel L., Helvie, Karla, Partridge, Ann H., Overmoyer, Beth, Winer, Eric P., Wagle, Nikhil, Tolaney, Sara M.
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Abstract OT1-19-01: The metastatic breast cancer project: Generating the clinical and genomic landscape of metastatic breast cancer through patient-partnered research
Wagle, Nikhil, Painter, Corrie, Anastasio, Elana, McGillicuddy, Mary, Jain, Esha, Hernandez, Tania G., Tomson, Brett N., Thomas, Beena, Abravanel, Daniel, Kim, Dewey, Balch, Sara, Damon, Alyssa L., Shah, Shahrayz, Ramos, Rafael, Sosa, Delia, Small, Ilan, Nguyen, Colleen, Winnicki, Sarah, Cusher, Taylor, Chastain, Parker, Dunphy, Michael, Zanudo, Jorge Gomez Tejeda, Tsegai, Netsanet, Sterlin, Lauren, Ulysse, Ulcha F., Boykin, Imani, Alao, Oyin, Golub, Todd R.
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Abstract PD6-02: The metastatic breast cancer project - Expanding the clinical, genomic, and transcriptomic landscape of metastatic breast cancer through patient-partnered research
Jain, Esha, Kim, Dewey, Zanudo, Jorge Gomez Tejeda, Balch, Sara, McGillicuddy, Mary, Tomson, Brett N., Hernandez, Tania G., Thomas, Beena S., Abravanel, Daniel L., Shah, Shahrayz, Ramos, Rafael, Sosa, Delia, Small, Ilan, Sterlin, Lauren, Winnicki, Sarah, Nguyen, Colleen, Dunphy, Micheal, Anastasio, Elana, Golub, Todd R., Painter, Corrie A., Wagle, Nikhil
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Inhibition of gamma-secretase activity inhibits tumor progression in a mouse model of pancreatic ductal adenocarcinoma
Plentz, Ruben, Park, Ji-Sun, Rhim, Andrew D, Abravanel, Daniel, Hezel, Aram F, Sharma, Sreenath V, Gurumurthy, Sushma, Deshpande, Vikram, Kenific, Candia, Settleman, Jeffrey, Majumder, Pradip K, Stanger, Ben Z, Bardeesy, Nabeel
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2009)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2009)
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Abstract PD6-03: Spatio-molecular dissection of the breast cancer metastatic microenvironment
Abravanel, Daniel L, Klughammer, Johanna, Blosser, Timothy, Goltsev, Yury, Jiang, Sizun, Bai, Yunjao, Murray, Evan, Alon, Shahar, Cui, Yi, Goodwin, Daniel R, Sinha, Anubhav, Cohen, Ofir, Slyper, Michal, Ashenberg, Orr, Dionne, Danielle, Jané-Valbuena, Judit, Porter, Caroline BM, Segerstolpe, Asa, Waldman, Julia, Vigneau, Sébastien, Helvie, Karla, Frangieh, Allison, DelloStritto, Laura, Patel, Miraj, We, Jingyi, Pfaff, Kathleen, Cullen, Nicole, Lako, Ana, Turner, Madison, Wakiro, Isaac, Napolitano, Sara, Kanodia, Abhay, Ortiz, Rebecca, MacKichan, Colin, Inga, Stephanie, Chen, Judy, Thorner, Aaron R, Rotem, Asaf, Rodig, Scott, Chen, Fei, Boyden, Edward S, Nolan, Garry P, Zhuang, Xiaowei, Rozenblatt-Rosen, Orit, Johnson, Bruce E, Regev, Aviv, Wagle, Nikhil
Published in Cancer research (Chicago, Ill.) (15.02.2022)
Published in Cancer research (Chicago, Ill.) (15.02.2022)
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Abstract GS6-05: A joint atlas of single-cell and bulk RNA-seq in metastatic breast cancer allows inference of oncogenic and drug-resistant transcriptional programs in malignant cells and the tumor microenvironment
Cohen, Ofir, Abravanel, Daniel, Slyper, Michal, Klughammer, Johanna, Jane-Valbuena, Judit, Helvie, Karla, Dellostritto, Laura, Frangieh, Allison, Vigneau, Sebastien, Wu, Jingyi, Mayorga, Angie, Waldman, Julia, Nguyen, Lan, Dionne, Danielle, Ashenberg, Orr, Hofree, Matan, Cuoco, Mike, Rodman, Christopher, Winer, Eric P, Lin, Nancy, Johnson, Bruce, Rotem, Asaf, Rozenblatt-Rosen, Orit, Regev, Aviv, Wagle, Nikhil
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract GS2-02: Acquired activating mutations in RTKs confer endocrine resistance in ER+ metastatic breast cancer through ER-reprogramming, MAPK signaling, and an induced stem-like cell state
Cohen, Ofir, Mao, Pingping, Nayar, Utthara, Buendia-Bue, Jorge E, Kim, Dewey, Jain, Esha, Helvie, Karla, Abravanel, Daniel, Kowalski, Kailey J, Kapstad, Christian, Freeman, Samuel, Adalsteinsson, Victor, Wander, Seth A, Waks, Adrienne G, Getz, Gad, Regev, Aviv, Winer, Eric Winer P, Lin, Nancy U Nancy U., Wagle, Nikhil
Published in Cancer research (Chicago, Ill.) (15.02.2020)
Published in Cancer research (Chicago, Ill.) (15.02.2020)
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Abstract GS03-09: Characterization and proposed therapeutic exploitation of fusion RNAs in metastatic breast cancers
Priedigkeit, Nolan, Lebrón-Torres, Alinés, Liao, Janny, Alberge, Jean-Baptiste, Morganti, Stefania, Weiss, Jakob, Zanudo, Jorge Gomez Tejeda, Grinshpun, Albert, Hughes, Melissa, Helvie, Karla, Sendrick, Kerry, Nguyen, Kyleen, Strauss, Sarah, Files, Janet, Lloyd, Maxwell, Wagle, Nikhil, Stewart, Chip, Winer, Eric, Johnson, Bruce, Li, Yvonne, Jeselsohn, Rinath, Tolaney, Sara, Abravanel, Daniel, Lin, Nancy, Parsons, Heather, Getz, Gad, Oesterreich, Steffi, Lee, Adrian, Golub, Todd
Published in Cancer research (Chicago, Ill.) (02.05.2024)
Published in Cancer research (Chicago, Ill.) (02.05.2024)
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Actomyosin purse strings: Renewable resources that make morphogenesis robust and resilient
Rodriguez-Diaz, Alice, Toyama, Yusuke, Abravanel, Daniel L., Wiemann, John M., Wells, Adrienne R., Tulu, U. Serdar, Edwards, Glenn S., Kiehart, Daniel P.
Published in HFSP Journal (01.08.2008)
Published in HFSP Journal (01.08.2008)
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Journal Article
Abstract 2894: Notch signaling promotes survival and recurrence of dormant mammary tumor cells following HER2/neu targeted therapy
Abravanel, Daniel L., Collins, Meredith A., Belka, George K., Pan, Tien-chi, Pant, Dhruv K., Sterner, Christopher J., Chodosh, Lewis A.
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Inference of single cell profiles from histology stains with the Single-Cell omics from Histology Analysis Framework (SCHAF)
Comiter, Charles, Vaishnav, Eeshit Dhaval, Ciampricotti, Metamia, Li, Bo, Yang, Yiming, Rodig, Scott J, Turner, Madison, Pfaff, Kathleen L, Jané-Valbuena, Judit, Slyper, Michal, Waldman, Julia, Vigneau, Sebastian, Wu, Jingyi, Blosser, Timothy R, Segerstolpe, Åsa, Abravanel, Daniel, Wagle, Nikil, Zhuang, Xiaowei, Rudin, Charles M, Klughammer, Johanna, Rozenblatt-Rosen, Orit, Kobayash-Kirschvink, Koseki J, Shu, Jian, Regev, Aviv
Published in bioRxiv : the preprint server for biology (23.03.2023)
Published in bioRxiv : the preprint server for biology (23.03.2023)
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SlideCNA: Spatial copy number alteration detection from Slide-seq-like spatial transcriptomics data
Zhang, Diane K, Segerstolpe, Asa, Slyper, Michal, Waldman, Julia, Murray, Evan, Cohen, Ofir, Orr Ashenberg, Abravanel, Daniel, Jané-Valbuena, Judit, Mages, Simon, Lako, Ana, Helvie, Karla, Rozenblatt-Rosen, Orit, Rodig, Scott, Chen, Fei, Wagle, Nikhil, Regev, Aviv, Klughammer, Johanna
Published in bioRxiv (27.11.2022)
Published in bioRxiv (27.11.2022)
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Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems
Shahar Alon, Goodwin, Daniel, Sinha, Anubhav, Wassie, Asmamaw, Chen, Fei, Daugharthy, Evan, Bando, Yosuke, Kajita, Atsushi, Xue, Andrew, Marrett, Karl, Prior, Robert, Cui, Yi, Payne, Andrew, Chun-Chen, Yao, Ho-Jun, Suk, Wang, Ru, Yu, Chih-Chieh, Tillberg, Paul, Reginato, Paul, Pak, Nikita, Liu, Songlei, Punthambaker, Sukanya, Iyer, Eswar, Kohman, Richie, Miller, Jeremy, Lein, Ed, Lako, Ana, Cullen, Nicole, Rodig, Scott, Helvie, Karla, Abravanel, Daniel, Wagle, Nikhil, Johnson, Bruce, Klughammer, Johanna, Slyper, Michal, Waldman, Julia, Jane-Valbuena, Judit, Rozenblatt-Rosen, Orit, Regev, Aviv, Church, George, Marblestone, Adam, Boyden, Edward S
Published in bioRxiv (15.05.2020)
Published in bioRxiv (15.05.2020)
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