Targeting GSK3 and Associated Signaling Pathways Involved in Cancer
Duda, Przemysław, Akula, Shaw M, Abrams, Stephen L, Steelman, Linda S, Martelli, Alberto M, Cocco, Lucio, Ratti, Stefano, Candido, Saverio, Libra, Massimo, Montalto, Giuseppe, Cervello, Melchiorre, Gizak, Agnieszka, Rakus, Dariusz, McCubrey, James A
Published in Cells (Basel, Switzerland) (30.04.2020)
Published in Cells (Basel, Switzerland) (30.04.2020)
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Journal Article
RAS/RAF/MEK/ERK, PI3K/PTEN/AKT/mTORC1 and TP53 pathways and regulatory miRs as therapeutic targets in hepatocellular carcinoma
Akula, Shaw M, Abrams, Stephen L, Steelman, Linda S, Emma, Maria R, Augello, Giuseppa, Cusimano, Antonella, Azzolina, Antonina, Montalto, Giuseppe, Cervello, Melchiorre, McCubrey, James A
Published in Expert opinion on therapeutic targets (02.11.2019)
Published in Expert opinion on therapeutic targets (02.11.2019)
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Journal Article
Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance
McCubrey, James A., Steelman, Linda S., Chappell, William H., Abrams, Stephen L., Wong, Ellis W.T., Chang, Fumin, Lehmann, Brian, Terrian, David M., Milella, Michele, Tafuri, Agostino, Stivala, Franca, Libra, Massimo, Basecke, Jorg, Evangelisti, Camilla, Martelli, Alberto M., Franklin, Richard A.
Published in Biochimica et biophysica acta (01.08.2007)
Published in Biochimica et biophysica acta (01.08.2007)
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Journal Article
Detection and monitoring of early dental caries and erosion using three-dimensional enhanced truncated-correlation photothermal coherence tomography imaging
Roointan, Sohrab, Tavakolian, Pantea, Sivagurunathan, Koneswaran S, Mandelis, Andreas, Abrams, Stephen H
Published in Journal of biomedical optics (01.04.2021)
Published in Journal of biomedical optics (01.04.2021)
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Journal Article
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging
Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Kempf, Ruth C, Long, Jacquelyn, Laidler, Piotr, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Stivala, Franca, Mazzarino, Maria C, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Bäsecke, Jörg, Cocco, Lucio, Evangelisti, Camilla, Martelli, Alberto M, Montalto, Giuseppe, Cervello, Melchiorre, McCubrey, James A
Published in Aging (Albany, NY.) (10.03.2011)
Published in Aging (Albany, NY.) (10.03.2011)
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Journal Article
Roles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cells
McCubrey, James A, Fitzgerald, Timothy L, Yang, Li V, Lertpiriyapong, Kvin, Steelman, Linda S, Abrams, Stephen L, Montalto, Giuseppe, Cervello, Melchiorre, Neri, Luca M, Cocco, Lucio, Martelli, Alberto M, Laidler, Piotr, Dulińska-Litewka, Joanna, Rakus, Dariusz, Gizak, Agnieszka, Nicoletti, Ferdinando, Falzone, Luca, Candido, Saverio, Libra, Massimo
Published in Oncotarget (21.02.2017)
Published in Oncotarget (21.02.2017)
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Journal Article
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance
McCubrey, James A, Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Franklin, Richard A, Montalto, Giuseppe, Cervello, Melchiorre, Libra, Massimo, Candido, Saverio, Malaponte, Grazia, Mazzarino, Maria C, Fagone, Paolo, Nicoletti, Ferdinando, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Chiarini, Francesca, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M
Published in Oncotarget (01.10.2012)
Published in Oncotarget (01.10.2012)
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Journal Article
Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy
Candido, Saverio, Abrams, Stephen L., Steelman, Linda S., Lertpiriyapong, Kvin, Fitzgerald, Timothy L., Martelli, Alberto M., Cocco, Lucio, Montalto, Giuseppe, Cervello, Melchiorre, Polesel, Jerry, Libra, Massimo, McCubrey, James A.
Published in Biochimica et biophysica acta (01.03.2016)
Published in Biochimica et biophysica acta (01.03.2016)
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Journal Article
Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response
McCubrey, James A, Steelman, Linda S, Chappell, William H, Abrams, Stephen L, Montalto, Giuseppe, Cervello, Melchiorre, Nicoletti, Ferdinando, Fagone, Paolo, Malaponte, Grazia, Mazzarino, Maria C, Candido, Saverio, Libra, Massimo, Bäsecke, Jörg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Milella, Michele, Tafuri, Agostino, Cocco, Lucio, Evangelisti, Camilla, Chiarini, Francesca, Martelli, Alberto M
Published in Oncotarget (01.09.2012)
Published in Oncotarget (01.09.2012)
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Journal Article
Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways
McCubrey, James A., Steelman, Linda S., Kempf, C. Ruth, Chappell, William H., Abrams, Stephen L., Stivala, Franca, Malaponte, Graziella, Nicoletti, Ferdinando, Libra, Massimo, Bäsecke, Jörg, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Cocco, Lucio, Martelli, Alberto M.
Published in Journal of cellular physiology (01.11.2011)
Published in Journal of cellular physiology (01.11.2011)
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Journal Article
Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy
Steelman, Linda S, Fitzgerald, Timothy, Lertpiriyapong, Kvin, Cocco, Lucio, Follo, Matilde Y, Martelli, Alberto M, Neri, Luca M, Marmiroli, Sandra, Libra, Massimo, Candido, Saverio, Nicoletti, Ferdinando, Scalisi, Aurora, Fenga, Concettina, Drobot, Lyudmyla, Rakus, Dariusz, Gizak, Agnieszka, Laidler, Piotr, Dulinska-Litewka, Joanna, Basecke, Joerg, Mijatovic, Sanja, Maksimovic-Ivanic, Danijela, Montalto, Giuseppe, Cervello, Melchiorre, Milella, Michelle, Tafuri, Agustino, Demidenko, Zoya, Abrams, Stephen L, McCubrey, James A
Published in Current pharmaceutical design (01.05.2016)
Published in Current pharmaceutical design (01.05.2016)
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Journal Article
Signaling intermediates (MAPK and PI3K) as therapeutic targets in NSCLC
Ciuffreda, Ludovica, Incani, Ursula Cesta, Steelman, Linda S, Abrams, Stephen L, Falcone, Italia, Curatolo, Anais Del, Chappell, William H, Franklin, Richard A, Vari, Sabrina, Cognetti, Francesco, McCubrey, James A, Milella, Michele
Published in Current pharmaceutical design (01.01.2014)
Published in Current pharmaceutical design (01.01.2014)
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Journal Article
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health
Chappell, William H, Steelman, Linda S, Long, Jacquelyn M, Kempf, Ruth C, Abrams, Stephen L, Franklin, Richard A, Bäsecke, Jörg, Stivala, Franca, Donia, Marco, Fagone, Paolo, Malaponte, Graziella, Mazzarino, Maria C, Nicoletti, Ferdinando, Libra, Massimo, Maksimovic-Ivanic, Danijela, Mijatovic, Sanja, Montalto, Giuseppe, Cervello, Melchiorre, Laidler, Piotr, Milella, Michele, Tafuri, Agostino, Bonati, Antonio, Evangelisti, Camilla, Cocco, Lucio, Martelli, Alberto M, McCubrey, James A
Published in Oncotarget (01.03.2011)
Published in Oncotarget (01.03.2011)
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Journal Article
Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis
McCubrey, James A., Abrams, Stephen L., Fitzgerald, Timothy L., Cocco, Lucio, Martelli, Alberto M., Montalto, Giuseppe, Cervello, Melchiorre, Scalisi, Aurora, Candido, Saverio, Libra, Massimo, Steelman, Linda S.
Published in Advances in biological regulation (01.01.2015)
Published in Advances in biological regulation (01.01.2015)
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Journal Article
New landscapes and horizons in hepatocellular carcinoma therapy
Cervello, Melchiorre, Emma, Maria R, Augello, Giuseppa, Cusimano, Antonella, Giannitrapani, Lydia, Soresi, Maurizio, Akula, Shaw M, Abrams, Stephen L, Steelman, Linda S, Gulino, Alessandro, Belmonte, Beatrice, Montalto, Giuseppe, McCubrey, James A
Published in Aging (Albany, NY.) (04.02.2020)
Published in Aging (Albany, NY.) (04.02.2020)
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Journal Article
p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3
Chappell, William H., Lehmann, Brian D., Terrian, David M., Abrams, Stephen L., Steelman, Linda S., McCubrey, James A.
Published in Cell cycle (Georgetown, Tex.) (15.12.2012)
Published in Cell cycle (Georgetown, Tex.) (15.12.2012)
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Journal Article
GSK-3 and miRs: Master regulators of therapeutic sensitivity of cancer cells
Duda, Przemysław, Akula, Shaw M., Abrams, Stephen L., Steelman, Linda S., Gizak, Agnieszka, Rakus, Dariusz, McCubrey, James A.
Published in Biochimica et biophysica acta. Molecular cell research (01.10.2020)
Published in Biochimica et biophysica acta. Molecular cell research (01.10.2020)
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Journal Article
Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells
Fitzgerald, Timothy L., Lertpiriyapong, Kvin, Cocco, Lucio, Martelli, Alberto M., Libra, Massimo, Candido, Saverio, Montalto, Giuseppe, Cervello, Melchiorre, Steelman, Linda, Abrams, Stephen L., McCubrey, James A.
Published in Advances in biological regulation (01.09.2015)
Published in Advances in biological regulation (01.09.2015)
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