Design and synthesis of novel chloropyridazine hybrids as promising anticancer agents acting by apoptosis induction and PARP-1 inhibition through a molecular hybridization strategy
Abdelrahman, Norhan A, Al-Karmalawy, Ahmed A, Jaballah, Maiy Y, Yahya, Galal, Sharaky, Marwa, Abouzid, Khaled A. M
Published in MedChemComm (20.03.2024)
Published in MedChemComm (20.03.2024)
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Novel 6-Aminoquinazolinone Derivatives as Potential Cross GT1-4 HCV NS5B Inhibitors
Nasr, Tamer, Aboshanab, Ahmed M, Mpekoulis, George, Drakopoulos, Antonios, Vassilaki, Niki, Zoidis, Grigoris, Abouzid, Khaled A M, Zaghary, Wafaa
Published in Viruses (01.12.2022)
Published in Viruses (01.12.2022)
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Lipid polymer hybrid nanocarriers as a combinatory platform for different anti-SARS-CoV-2 drugs supported by computational studies
Abdel-Bar, Hend Mohamed, Abdallah, Inas A, Fayed, Marwa A. A, Moatasim, Yassmin, Mostafa, Ahmed, El-Behairy, Mohammed Farrag, Elimam, Hanan, Elshaier, Yaseen A. M. M, Abouzid, Khaled A. M
Published in RSC advances (23.08.2021)
Published in RSC advances (23.08.2021)
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Drug repurposing of pyrazolotriazine derivatives as potential anti-SARS-CoV-2 agents: in vitro and in silico studies
Oudah, Khulood H., Najm, Mazin A. A., Barghash, Reham F., Kutkat, Omnia, GabAllah, Mohamed, Albohy, Amgad, Abouzid, Khaled A. M.
Published in BMC chemistry (16.07.2024)
Published in BMC chemistry (16.07.2024)
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Design, synthesis, and biological evaluation of new thieno[2,3-d] pyrimidine derivatives as targeted therapy for PI3K with molecular modelling study
Elmenier, Fatma M., Lasheen, Deena S., Abouzid, Khaled A. M.
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (01.12.2022)
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Fragment merging approach for design, synthesis, and biological assessment of urea/acetyl hydrazide clubbed thienopyrimidine derivatives as GSK-3β inhibitors
Saleh, Joseph S., Abd El Hadi, Soha R., Ibrahim, Hany S., Elrazaz, Eman Z., Abouzid, Khaled A. M.
Published in BMC chemistry (27.09.2023)
Published in BMC chemistry (27.09.2023)
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Targeting YAP Degradation by a Novel 1,2,4-Oxadiazole Derivative via Restoration of the Function of the Hippo Pathway
Dokla, Eman M. E, Fang, Chun-Sheng, Chu, Po-Chen, Chang, Chih-Shiang, Abouzid, Khaled A. M, Chen, Ching S
Published in ACS medicinal chemistry letters (09.04.2020)
Published in ACS medicinal chemistry letters (09.04.2020)
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Design and Synthesis of New Tetrazolyl- and Carboxy-biphenylylmethyl-quinazolin-4-one Derivatives as Angiotensin II AT1 Receptor Antagonists
Ismail, Mohamed A. H, Barker, Stewart, Abou El Ella, Dalal A, Abouzid, Khaled A. M, Toubar, Rabab A, Todd, Matthew H
Published in Journal of medicinal chemistry (09.03.2006)
Published in Journal of medicinal chemistry (09.03.2006)
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Design, synthesis and biological evaluation of a new thieno[2,3-d]pyrimidine-based urea derivative with potential antitumor activity against tamoxifen sensitive and resistant breast cancer cell lines
Sharaky, Marwa, Kamel, Marwa, Aziz, Marwa A., Omran, Mervat, Rageh, Monira M., Abouzid, Khaled A. M., Shouman, Samia A.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2020)
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Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibition
Elmeligie, Salwa, Aboul-Magd, Asmaa M., Lasheen, Deena S., Ibrahim, Tamer M., Abdelghany, Tamer M., Khojah, Sohair M., Abouzid, Khaled A. M.
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2019)
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Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles
Hossam, Monia, Lasheen, Deena S., Abouzid, Khaled A. M.
Published in Archiv der Pharmazie (Weinheim) (01.08.2016)
Published in Archiv der Pharmazie (Weinheim) (01.08.2016)
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Design and Synthesis of New Quinoxaline Derivatives as Anticancer Agents and Apoptotic Inducers
El Newahie, Aliya M S, Nissan, Yassin M, Ismail, Nasser S M, Abou El Ella, Dalal A, Khojah, Sohair M, Abouzid, Khaled A M
Published in Molecules (Basel, Switzerland) (25.03.2019)
Published in Molecules (Basel, Switzerland) (25.03.2019)
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Molecular design, synthesis and biological evaluation of novel 1,2,5-trisubstituted benzimidazole derivatives as cytotoxic agents endowed with ABCB1 inhibitory action to overcome multidrug resistance in cancer cells
Abdelhafiz, Abeer H. A., Serya, Rabah A. T., Lasheen, Deena S., Wang, Nessa, Sobeh, Mansour, Wink, Michael, Abouzid, Khaled A. M.
Published in Journal of enzyme inhibition and medicinal chemistry (31.12.2022)
Published in Journal of enzyme inhibition and medicinal chemistry (31.12.2022)
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Molecular design, synthesis and in vitro biological evaluation of thienopyrimidine-hydroxamic acids as chimeric kinase HDAC inhibitors: a challenging approach to combat cancer
Abdel-Atty, Mona M., Farag, Nahla A., Serya, Rabah A. T., Abouzid, Khaled A. M., Mowafy, Samar
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
Published in Journal of enzyme inhibition and medicinal chemistry (01.01.2021)
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