Blood flow-induced Notch activation and endothelial migration enable vascular remodeling in zebrafish embryos
Weijts, Bart, Gutierrez, Edgar, Saikin, Semion K., Ablooglu, Ararat J., Traver, David, Groisman, Alex, Tkachenko, Eugene
Published in Nature communications (14.12.2018)
Published in Nature communications (14.12.2018)
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Journal Article
PARP15 is a Susceptibility Locus for Clarkson Disease (Monoclonal Gammopathy-Associated Systemic Capillary Leak Syndrome)
Chan, Eunice C, Ablooglu, Ararat J, Ghosh, Chandra C, Desai, Abhishek, Schaible, Niccole, Chen, Xiuying, Zhao, Ming, Olano, M Renee, Ganesan, Sundar, Lack, Justin B, Krishnan, Ramaswamy, Parikh, Samir M, Druey, Kirk M
Published in Arteriosclerosis, thrombosis, and vascular biology (31.10.2024)
Published in Arteriosclerosis, thrombosis, and vascular biology (31.10.2024)
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Journal Article
Intrinsic endothelial hyperresponsiveness to inflammatory mediators drives acute episodes in models of Clarkson disease
Ablooglu, Ararat J, Chen, Wei-Sheng, Xie, Zhihui, Desai, Abhishek, Paul, Subrata, Lack, Justin B, Scott, Linda A, Eisch, A Robin, Dudek, Arkadiusz Z, Parikh, Samir M, Druey, Kirk M
Published in The Journal of clinical investigation (15.05.2024)
Published in The Journal of clinical investigation (15.05.2024)
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Journal Article
Interaction of kindlin-2 with integrin β3 promotes outside-in signaling responses by the αVβ3 vitronectin receptor
Liao, Zhongji, Kato, Hisashi, Pandey, Manjula, Cantor, Joseph M., Ablooglu, Ararat J., Ginsberg, Mark H., Shattil, Sanford J.
Published in Blood (19.03.2015)
Published in Blood (19.03.2015)
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Journal Article
Antithrombotic effects of targeting αIIbβ3 signaling in platelets
Ablooglu, Ararat J., Kang, Jian, Petrich, Brian G., Ginsberg, Mark H., Shattil, Sanford J.
Published in Blood (09.04.2009)
Published in Blood (09.04.2009)
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Journal Article
A ligand-independent Tie2-activating antibody reduces vascular leakage in models of Clarkson disease
Ablooglu, Ararat J, Desai, Abhishek, Yoo, Jin-San, Park, Cheon Ho, Lee, Eun-Ah, Kim, Bu Yeon, Park, Hyunsun, Lee, Young Ae, Shim, Sang Ryeol, Lee, Weon Sup, Druey, Kirk M
Published in Science advances (17.11.2023)
Published in Science advances (17.11.2023)
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Journal Article
Mechanism-based design of a protein kinase inhibitor
Hubbard, Stevan R, Cole, Philip A, Parang, Keykavous, Till, Jeffrey H, Ablooglu, Ararat J, Kohanski, Ronald A
Published in Nature structural & molecular biology (01.01.2001)
Published in Nature structural & molecular biology (01.01.2001)
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Journal Article
Multiple Activation Loop Conformations and Their Regulatory Properties in the Insulin Receptor's Kinase Domain
Ablooglu, Ararat J., Frankel, Mark, Rusinova, Elena, Ross, John B. Alexander, Kohanski, Ronald A.
Published in The Journal of biological chemistry (14.12.2001)
Published in The Journal of biological chemistry (14.12.2001)
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Journal Article
Probing the Catalytic Mechanism of the Insulin Receptor Kinase with a Tetrafluorotyrosine-containing Peptide Substrate
Ablooglu, Ararat J., Till, Jeffrey H., Kim, Kyonghee, Parang, Keykavous, Cole, Philip A., Hubbard, Stevan R., Kohanski, Ronald A.
Published in The Journal of biological chemistry (29.09.2000)
Published in The Journal of biological chemistry (29.09.2000)
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Journal Article
Integrin αV is necessary for gastrulation movements that regulate vertebrate body asymmetry
Ablooglu, Ararat J., Tkachenko, Eugene, Kang, Jian, Shattil, Sanford J.
Published in Development (Cambridge) (15.10.2010)
Published in Development (Cambridge) (15.10.2010)
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Journal Article
The antithrombotic potential of selective blockade of talin-dependent integrin αIIbβ3 (platelet GPIIb–IIIa) activation
Petrich, Brian G., Fogelstrand, Per, Partridge, Anthony W., Yousefi, Nima, Ablooglu, Ararat J., Shattil, Sanford J., Ginsberg, Mark H.
Published in The Journal of clinical investigation (01.08.2007)
Published in The Journal of clinical investigation (01.08.2007)
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Journal Article
Conformational changes in the activation loop of the insulin receptor's kinase domain
FRANKEL, MARK, BISHOP, STEVEN M., ABLOOGLU, ARARAT J., HAN, YUAN-PING, KOHANSKI, RONALD A.
Published in Protein science (01.10.1999)
Published in Protein science (01.10.1999)
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Journal Article
Crystallographic and Solution Studies of an Activation Loop Mutant of the Insulin Receptor Tyrosine Kinase
Till, Jeffrey H., Ablooglu, Ararat J., Frankel, Mark, Bishop, Steven M., Kohanski, Ronald A., Hubbard, Stevan R.
Published in The Journal of biological chemistry (30.03.2001)
Published in The Journal of biological chemistry (30.03.2001)
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Journal Article
Intrasteric Inhibition of ATP Binding Is Not Required To Prevent Unregulated Autophosphorylation or Signaling by the Insulin Receptor
Frankel, Mark, Ablooglu, Ararat J., Leone, Joseph W., Rusinova, Elena, Ross, J. B. Alexander, Heinrikson, Robert L., Kohanski, Ronald A.
Published in Molecular and Cellular Biology (01.07.2001)
Published in Molecular and Cellular Biology (01.07.2001)
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Journal Article
Partial Activation of the Insulin Receptor Kinase Domain by Juxtamembrane Autophosphorylation
Cann, Aaron Darius, Bishop, Steven M, Ablooglu, Ararat J, Kohanski, Ronald A
Published in Biochemistry (Easton) (11.08.1998)
Published in Biochemistry (Easton) (11.08.1998)
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Journal Article
Integrin aV is necessary for gastrulation movements that regulate vertebrate body asymmetry
Ablooglu, Ararat J, Tkachenko, Eugene, Kang, Jian, Shattil, Sanford J
Published in Development (Cambridge) (15.10.2010)
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Published in Development (Cambridge) (15.10.2010)
Journal Article