Engineered heart tissues and induced pluripotent stem cells: Macro- and microstructures for disease modeling, drug screening, and translational studies
Tzatzalos, Evangeline, Abilez, Oscar J., Shukla, Praveen, Wu, Joseph C.
Published in Advanced drug delivery reviews (15.01.2016)
Published in Advanced drug delivery reviews (15.01.2016)
Get full text
Journal Article
Chemically defined generation of human cardiomyocytes
Burridge, Paul W, Matsa, Elena, Shukla, Praveen, Lin, Ziliang C, Churko, Jared M, Ebert, Antje D, Lan, Feng, Diecke, Sebastian, Huber, Bruno, Mordwinkin, Nicholas M, Plews, Jordan R, Abilez, Oscar J, Cui, Bianxiao, Gold, Joseph D, Wu, Joseph C
Published in Nature methods (01.08.2014)
Published in Nature methods (01.08.2014)
Get full text
Journal Article
Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells
Lan, Feng, Lee, Andrew S., Liang, Ping, Sanchez-Freire, Veronica, Nguyen, Patricia K., Wang, Li, Han, Leng, Yen, Michelle, Wang, Yongming, Sun, Ning, Abilez, Oscar J., Hu, Shijun, Ebert, Antje D., Navarrete, Enrique G., Simmons, Chelsey S., Wheeler, Matthew, Pruitt, Beth, Lewis, Richard, Yamaguchi, Yoshinori, Ashley, Euan A., Bers, Donald M., Robbins, Robert C., Longaker, Michael T., Wu, Joseph C.
Published in Cell stem cell (03.01.2013)
Published in Cell stem cell (03.01.2013)
Get full text
Journal Article
Multiscale Computational Models for Optogenetic Control of Cardiac Function
Abilez, Oscar J., Wong, Jonathan, Prakash, Rohit, Deisseroth, Karl, Zarins, Christopher K., Kuhl, Ellen
Published in Biophysical journal (21.09.2011)
Published in Biophysical journal (21.09.2011)
Get full text
Journal Article
Human Engineered Heart Muscles Engraft and Survive Long Term in a Rodent Myocardial Infarction Model
Riegler, Johannes, Tiburcy, Malte, Ebert, Antje, Tzatzalos, Evangeline, Raaz, Uwe, Abilez, Oscar J, Shen, Qi, Kooreman, Nigel G, Neofytou, Evgenios, Chen, Vincent C, Wang, Mouer, Meyer, Tim, Tsao, Philip S, Connolly, Andrew J, Couture, Larry A, Gold, Joseph D, Zimmermann, Wolfram H, Wu, Joseph C
Published in Circulation research (25.09.2015)
Published in Circulation research (25.09.2015)
Get full text
Journal Article
An in Vivo miRNA Delivery System for Restoring Infarcted Myocardium
Yang, Huaxiao, Qin, Xulei, Wang, Huiyuan, Zhao, Xin, Liu, Yonggang, Wo, Hung-Ta, Liu, Chun, Nishiga, Masataka, Chen, Haodong, Ge, Jing, Sayed, Nazish, Abilez, Oscar J, Ding, Dan, Heilshorn, Sarah C, Li, Kai
Published in ACS nano (24.09.2019)
Published in ACS nano (24.09.2019)
Get full text
Journal Article
Effect of Human Donor Cell Source on Differentiation and Function of Cardiac Induced Pluripotent Stem Cells
Sanchez-Freire, Veronica, PhD, Lee, Andrew S., PhD, Hu, Shijun, PhD, Abilez, Oscar J., MD, Liang, Ping, PhD, Lan, Feng, PhD, Huber, Bruno C., MD, Ong, Sang-Ging, PhD, Hong, Wan Xing, MS, Huang, Mei, PhD, Wu, Joseph C., MD, PhD
Published in Journal of the American College of Cardiology (05.08.2014)
Published in Journal of the American College of Cardiology (05.08.2014)
Get full text
Journal Article
iPSC-derived cardiomyocytes reveal abnormal TGF-β signalling in left ventricular non-compaction cardiomyopathy
Kodo, Kazuki, Ong, Sang-Ging, Jahanbani, Fereshteh, Termglinchan, Vittavat, Hirono, Keiichi, InanlooRahatloo, Kolsoum, Ebert, Antje D., Shukla, Praveen, Abilez, Oscar J., Churko, Jared M., Karakikes, Ioannis, Jung, Gwanghyun, Ichida, Fukiko, Wu, Sean M., Snyder, Michael P., Bernstein, Daniel, Wu, Joseph C.
Published in Nature cell biology (01.10.2016)
Published in Nature cell biology (01.10.2016)
Get full text
Journal Article
Passive Stretch Induces Structural and Functional Maturation of Engineered Heart Muscle as Predicted by Computational Modeling
Abilez, Oscar J., Tzatzalos, Evangeline, Yang, Huaxiao, Zhao, Ming‐Tao, Jung, Gwanghyun, Zöllner, Alexander M., Tiburcy, Malte, Riegler, Johannes, Matsa, Elena, Shukla, Praveen, Zhuge, Yan, Chour, Tony, Chen, Vincent C., Burridge, Paul W., Karakikes, Ioannis, Kuhl, Ellen, Bernstein, Daniel, Couture, Larry A., Gold, Joseph D., Zimmermann, Wolfram H., Wu, Joseph C.
Published in Stem cells (Dayton, Ohio) (01.02.2018)
Published in Stem cells (Dayton, Ohio) (01.02.2018)
Get full text
Journal Article
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy
Sun, Ning, Yazawa, Masayuki, Liu, Jianwei, Han, Leng, Sanchez-Freire, Veronica, Abilez, Oscar J, Navarrete, Enrique G, Hu, Shijun, Wang, Li, Lee, Andrew, Pavlovic, Aleksandra, Lin, Shin, Chen, Rui, Hajjar, Roger J, Snyder, Michael P, Dolmetsch, Ricardo E, Butte, Manish J, Ashley, Euan A, Longaker, Michael T, Robbins, Robert C, Wu, Joseph C
Published in Science translational medicine (18.04.2012)
Published in Science translational medicine (18.04.2012)
Get more information
Journal Article
Transcriptome analysis of non human primate-induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer culture vs. 3D engineered heart tissue
Yang, Huaxiao, Shao, Ningyi, Holmström, Alexandra, Zhao, Xin, Chour, Tony, Chen, Haodong, Itzhaki, Ilanit, Wu, Haodi, Ameen, Mohamed, Cunningham, Nathan J, Tu, Chengyi, Zhao, Ming-Tao, Tarantal, Alice F, Abilez, Oscar J, Wu, Joseph C
Published in Cardiovascular research (27.07.2021)
Published in Cardiovascular research (27.07.2021)
Get full text
Journal Article
Partial Reprogramming of Pluripotent Stem Cell-Derived Cardiomyocytes into Neurons
Chuang, Wenpo, Sharma, Arun, Shukla, Praveen, Li, Guang, Mall, Moritz, Rajarajan, Kuppusamy, Abilez, Oscar J., Hamaguchi, Ryoko, Wu, Joseph C., Wernig, Marius, Wu, Sean M.
Published in Scientific reports (22.03.2017)
Published in Scientific reports (22.03.2017)
Get full text
Journal Article
Treatment of volumetric muscle loss in mice using nanofibrillar scaffolds enhances vascular organization and integration
Nakayama, Karina H., Quarta, Marco, Paine, Patrick, Alcazar, Cynthia, Karakikes, Ioannis, Garcia, Victor, Abilez, Oscar J., Calvo, Nicholas S., Simmons, Chelsey S., Rando, Thomas A., Huang, Ngan F.
Published in Communications biology (07.05.2019)
Published in Communications biology (07.05.2019)
Get full text
Journal Article
Vascular anastomosis using controlled phase transitions in poloxamer gels
Chang, Edward I, Galvez, Michael G, Glotzbach, Jason P, Hamou, Cynthia D, El-ftesi, Samyra, Rappleye, C Travis, Sommer, Kristin-Maria, Rajadas, Jayakumar, Abilez, Oscar J, Fuller, Gerald G, Longaker, Michael T, Gurtner, Geoffrey C
Published in Nature medicine (01.09.2011)
Published in Nature medicine (01.09.2011)
Get full text
Journal Article
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue
Ardehali, Reza, Ali, Shah R., Inlay, Matthew A., Abilez, Oscar J., Chen, Michael Q., Blauwkamp, Timothy A., Yazawa, Masayuki, Gong, Yongquan, Nusse, Roeland, Drukker, Micha, Weissman, Irving L.
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (26.02.2013)
Get full text
Journal Article