Complement is activated by elevated IgG3 hexameric platforms and deposits C4b onto distinct antibody domains
Abendstein, Leoni, Dijkstra, Douwe J., Tjokrodirijo, Rayman T. N., van Veelen, Peter A., Trouw, Leendert A., Hensbergen, Paul J., Sharp, Thomas H.
Published in Nature communications (07.07.2023)
Published in Nature communications (07.07.2023)
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The Gpr1-regulated Sur7 family protein Sfp2 is required for hyphal growth and cell wall stability in the mycoparasite Trichoderma atroviride
Atanasova, Lea, Gruber, Sabine, Lichius, Alexander, Radebner, Theresa, Abendstein, Leoni, Münsterkötter, Martin, Stralis-Pavese, Nancy, Łabaj, Paweł P., Kreil, David P., Zeilinger, Susanne
Published in Scientific reports (13.08.2018)
Published in Scientific reports (13.08.2018)
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Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators
Wang, Haiyu, van de Bovenkamp, Fleur S, Dijkstra, Douwe J, Abendstein, Leoni, Borggreven, Nicole V, Pool, Jos, Zuijderduijn, Rob, Gstöttner, Christoph, Gelderman, Kyra A, Damelang, Timon, Vidarsson, Gestur, Blom, Anna M, Domínguez-Vega, Elena, Parren, Paul W H I, Sharp, Thomas H, Trouw, Leendert A
Published in Frontiers in immunology (16.05.2024)
Published in Frontiers in immunology (16.05.2024)
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99 Targeted complement inhibition using engineered bispecific antibodies that bind local antigens and endogenous complement regulators as a novel therapeutic approach
Trouw, Leendert, Dijkstra, Douwe, Abendstein, Leoni, Gelderman, Kyra, Parren, Paul, Sharp, Thomas, van den Bovenkamp, Fleur
Published in Immunobiology (1979) (01.09.2023)
Published in Immunobiology (1979) (01.09.2023)
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One-Pot Synthesis of Defined-Length ssDNA for Multiscaffold DNA Origami
Noteborn, Willem E. M, Abendstein, Leoni, Sharp, Thomas H
Published in Bioconjugate chemistry (20.01.2021)
Published in Bioconjugate chemistry (20.01.2021)
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163 Single cell sorting and cloning of human anti-C1q autoantibodies reveals specificity for solid-phase C1q and capacity to engage Fc receptors
Dijkstra, Douwe, van de Bovenkamp, Sanne, Abendstein, Leoni, de Vor, Lisanne, Rooijakkers, Suzan, Gelderman, Kyra, Sharp, Thomas, Parren, Paul, Trouw, Leendert
Published in Immunobiology (1979) (01.09.2023)
Published in Immunobiology (1979) (01.09.2023)
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59 DNA-templated antibody complexes provide insights into the geometric requirements of human complement activation
Abendstein, Leoni, Noteborn, Willem E.M., Veenman, Luc S., Dijkstra, Douwe J., van de Bovenkamp, Fleur S., Trouw, Leendert A., Sharp, Thomas H.
Published in Immunobiology (1979) (01.09.2023)
Published in Immunobiology (1979) (01.09.2023)
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DNA Nanostructure-Templated Antibody Complexes Provide Insights into the Geometric Requirements of Human Complement Cascade Activation
Abendstein, Leoni, Noteborn, Willem E. M., Veenman, Luc S., Dijkstra, Douwe J., van de Bovenkamp, Fleur S., Trouw, Leendert A., Sharp, Thomas H.
Published in Journal of the American Chemical Society (15.05.2024)
Published in Journal of the American Chemical Society (15.05.2024)
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Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation
Dijkstra, Douwe J, van de Bovenkamp, Fleur S, Abendstein, Leoni, Zuijderduijn, Rob, Pool, Jos, Kramer, Cynthia S M, Slot, Linda M, Drijfhout, Jan W, de Vor, Lisanne, Gelderman, Kyra A, Rooijakkers, Suzan H M, Zaldumbide, Arnaud, Vidarsson, Gestur, Sharp, Thomas H, Parren, Paul W H I, Trouw, Leendert A
Published in Proceedings of the National Academy of Sciences - PNAS (12.12.2023)
Published in Proceedings of the National Academy of Sciences - PNAS (12.12.2023)
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