Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
Craig, Jonathan M, Mills, Maria, Kim, Hwanhee C, Huang, Jesse R, Abell, Sarah J, Mount, Jonathan W, Gundlach, Jens H, Neuman, Keir C, Laszlo, Andrew H
Published in Nucleic acids research (14.10.2022)
Published in Nucleic acids research (14.10.2022)
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Journal Article
Nanopores map the acid-base properties of a single site in a single DNA molecule
Smith, Drew C, Thomas, Christopher A, Craig, Jonathan M, Brinkerhoff, Henry, Abell, Sarah J, Franzi, Michaela C, Carrasco, Jessica D, Hoshika, Shuichi, Benner, Steven A, Gundlach, Jens H, Laszlo, Andrew H
Published in Nucleic acids research (22.07.2024)
Published in Nucleic acids research (22.07.2024)
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Journal Article
Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Published in Nucleic acids research (22.09.2023)
Published in Nucleic acids research (22.09.2023)
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Journal Article
Assessing Readability of an 8‑Letter Expanded Deoxyribonucleic Acid Alphabet with Nanopores
Thomas, Christopher A., Craig, Jonathan M., Hoshika, Shuichi, Brinkerhoff, Henry, Huang, Jesse R., Abell, Sarah J., Kim, Hwanhee C., Franzi, Michaela C., Carrasco, Jessica D., Kim, Hyo-Joong, Smith, Drew C., Gundlach, Jens H., Benner, Steven A., Laszlo, Andrew H.
Published in Journal of the American Chemical Society (10.04.2023)
Published in Journal of the American Chemical Society (10.04.2023)
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Journal Article
Nanopore Sequencing of an Expanded Genetic Alphabet Reveals High-Fidelity Replication of a Predominantly Hydrophobic Unnatural Base Pair
Ledbetter, Michael P, Craig, Jonathan M, Karadeema, Rebekah J, Noakes, Matthew T, Kim, Hwanhee C, Abell, Sarah J, Huang, Jesse R, Anderson, Brooke A, Krishnamurthy, Ramanarayanan, Gundlach, Jens H, Romesberg, Floyd E
Published in Journal of the American Chemical Society (05.02.2020)
Published in Journal of the American Chemical Society (05.02.2020)
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Journal Article
Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution
Laszlo, Andrew H, Craig, Jonathan M, Gavrilov, Momčilo, Tippana, Ramreddy, Nova, Ian C, Huang, Jesse R, Kim, Hwanhee C, Abell, Sarah J, deCampos-Stairiker, Mallory, Mount, Jonathan W, Bowman, Jasmine L, Baker, Katherine S, Higinbotham, Hugh, Bobrovnikov, Dmitriy, Ha, Taekjip, Gundlach, Jens H
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2022)
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Journal Article
Mechanism of an animal toxin-antidote system
Caro, Lews, Wei, Aguan D, Thomas, Christopher A, Posch, Galen, Uremis, Ahmet, Franzi, Michaela C, Abell, Sarah J, Laszlo, Andrew H, Gundlach, Jens H, Ramirez, Jan-Marino, Ailion, Michael
Published in bioRxiv (13.06.2024)
Published in bioRxiv (13.06.2024)
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Journal Article
C-Glycoside DNA bases from an artificially expanded genetic information system reduce processivity in a SF2 helicase as revealed by nanopore tweezers
Thomas, Christopher A., Craig, Jonathan M., Hoshika, Shuichi, Laszlo, Andrew H., Huang, Jesse R., Abell, Sarah J., Kim, Hwanhee C., Carrasco, Jessica, Franzi, Michaela C., Benner, Steven A., Gundlach, Jens H.
Published in Biophysical journal (11.02.2022)
Published in Biophysical journal (11.02.2022)
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Journal Article
SV40 Large T Antigen Helicase Unwinds Double-Stranded DNA in Single-Nucleotide Steps as Revealed by Nanopore Tweezers
Thomas, Christopher A., Craig, Jonathan M., Laszlo, Andrew H., Nova, Ian C., Xie, Sherry, Huang, Jesse R., Kim, Hwanhee C., Abell, Sarah J., Yardimci, Hasan, Gundlach, Jens H.
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Uncovering the Molecular Basis for Sequence-Dependent Translocation in a Superfamily 2 Helicase using High-Resolution Nanopore Tweezers
Craig, Jonathan M., Marx, Sinduja K., Laszlo, Andrew H., Nova, Ian C., Kim, Hwanhee C., Huang, Jesse R., Abell, Sarah J., Gundlach, Jens H.
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
de novo Design of Ion Conducting Transmembrane Protein Nanopores
Marx, Sinduja K., Vorobieva, Anastassia, Chow, Cameron, Craig, Jonathan M., Kim, Hwanhee C., Abell, Sarah J., Huang, Jesse, Gerben, Stacey, Baker, David, Gundlach, Jens H.
Published in Biophysical journal (07.02.2020)
Published in Biophysical journal (07.02.2020)
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Journal Article
Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry D, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Published in bioRxiv (08.10.2022)
Published in bioRxiv (08.10.2022)
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Paper
Inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
Marx, Sinduja K, Mickolajczyk, Keith J, Craig, Jonathan M, Thomas, Christopher A, Pfeffer, Akira M, Abell, Sarah J, Carrasco, Jessica D, Franzi, Michaela C, Huang, Jesse R, Kim, Hwanhee C, Brinkerhoff, Henry D, Kapoor, Tarun M, Gundlach, Jens H, Laszlo, Andrew H
Published in bioRxiv : the preprint server for biology (08.10.2022)
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Published in bioRxiv : the preprint server for biology (08.10.2022)
Journal Article
Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
Craig, Jonathan M, Mills, Maria, Laszlo, Andrew, Kim, Hwanhee C, Abell, Sarah J, Huang, Jesse R, Mount, Jonathan W, Neuman, Keir C, Gundlach, Jens H
Published in bioRxiv (23.09.2021)
Published in bioRxiv (23.09.2021)
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Paper
Sequence-dependent mechanochemical coupling of helicase translocation and unwinding at single-nucleotide resolution
Laszlo, Andrew H, Craig, Jonathan M, Gavrilov, Momčilo, Tippana, Ramreddy, Nova, Ian C, Huang, Jesse R, Kim, Hwanhee C, Abell, Sarah J, Mallory Decampos-Stairiker, Mount, Jonathan W, Bowman, Jasmine L, Baker, Katherine S, Higinbotham, Hugh, Bobrovnikov, Dmitriy, Ha, Taekjip, Gundlach, Jens H
Published in bioRxiv (11.02.2022)
Published in bioRxiv (11.02.2022)
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Paper