Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome
Middleton, Elizabeth A., He, Xue-Yan, Denorme, Frederik, Campbell, Robert A., Ng, David, Salvatore, Steven P., Mostyka, Maria, Baxter-Stoltzfus, Amelia, Borczuk, Alain C., Loda, Massimo, Cody, Mark J., Manne, Bhanu Kanth, Portier, Irina, Harris, Estelle S., Petrey, Aaron C., Beswick, Ellen J., Caulin, Aleah F., Iovino, Anthony, Abegglen, Lisa M., Weyrich, Andrew S., Rondina, Matthew T., Egeblad, Mikala, Schiffman, Joshua D., Yost, Christian Con
Published in Blood (03.09.2020)
Published in Blood (03.09.2020)
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Potential Mechanisms for Cancer Resistance in Elephants and Comparative Cellular Response to DNA Damage in Humans
Abegglen, Lisa M, Caulin, Aleah F, Chan, Ashley, Lee, Kristy, Robinson, Rosann, Campbell, Michael S, Kiso, Wendy K, Schmitt, Dennis L, Waddell, Peter J, Bhaskara, Srividya, Jensen, Shane T, Maley, Carlo C, Schiffman, Joshua D
Published in JAMA : the journal of the American Medical Association (03.11.2015)
Published in JAMA : the journal of the American Medical Association (03.11.2015)
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Journal Article
Accelerated Evolution in Distinctive Species Reveals Candidate Elements for Clinically Relevant Traits, Including Mutation and Cancer Resistance
Ferris, Elliott, Abegglen, Lisa M., Schiffman, Joshua D., Gregg, Christopher
Published in Cell reports (Cambridge) (06.03.2018)
Published in Cell reports (Cambridge) (06.03.2018)
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Journal Article
Elephant Genomes Reveal Accelerated Evolution in Mechanisms Underlying Disease Defenses
Tollis, Marc, Ferris, Elliott, Campbell, Michael S, Harris, Valerie K, Rupp, Shawn M, Harrison, Tara M, Kiso, Wendy K, Schmitt, Dennis L, Garner, Michael M, Aktipis, Christina Athena, Maley, Carlo C, Boddy, Amy M, Yandell, Mark, Gregg, Christopher, Schiffman, Joshua D, Abegglen, Lisa M
Published in Molecular biology and evolution (01.09.2021)
Published in Molecular biology and evolution (01.09.2021)
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Journal Article
ATM and ATR Activation Through Crosstalk Between DNA Damage Response Pathways
Fedak, Elizabeth A., Adler, Frederick R., Abegglen, Lisa M., Schiffman, Joshua D.
Published in Bulletin of mathematical biology (01.04.2021)
Published in Bulletin of mathematical biology (01.04.2021)
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Journal Article
Bridging clinic and wildlife care with AI-powered pan-species computational pathology
AbdulJabbar, Khalid, Castillo, Simon P, Hughes, Katherine, Davidson, Hannah, Boddy, Amy M, Abegglen, Lisa M, Minoli, Lucia, Iussich, Selina, Murchison, Elizabeth P, Graham, Trevor A, Spiro, Simon, Maley, Carlo C, Aresu, Luca, Palmieri, Chiara, Yuan, Yinyin
Published in Nature communications (26.04.2023)
Published in Nature communications (26.04.2023)
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Journal Article
Cancer therapeutics inspired by defense mechanisms in the animal kingdom
Noble, Kathleen, Rohaj, Aarushi, Abegglen, Lisa M., Schiffman, Joshua D.
Published in Evolutionary applications (01.08.2020)
Published in Evolutionary applications (01.08.2020)
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Journal Article
Identification of African Elephant Polyomavirus in wild elephants and the creation of a vector expressing its viral tumor antigens to transform elephant primary cells
Pearson, Virginia R, Bosse, Jens B, Koyuncu, Orkide O, Scherer, Julian, Toruno, Cristhian, Robinson, Rosann, Abegglen, Lisa M, Schiffman, Joshua D, Enquist, Lynn W, Rall, Glenn F
Published in PloS one (05.02.2021)
Published in PloS one (05.02.2021)
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Journal Article
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
Light, Nicholas, Layeghifard, Mehdi, Attery, Ayush, Subasri, Vallijah, Zatzman, Matthew, Anderson, Nathaniel D, Hatkar, Rupal, Blay, Sasha, Chen, David, Novokmet, Ana, Fuligni, Fabio, Tran, James, de Borja, Richard, Agarwal, Himanshi, Waldman, Larissa, Abegglen, Lisa M, Albertson, Daniel, Finlay, Jonathan L, Hansford, Jordan R, Behjati, Sam, Villani, Anita, Gerstung, Moritz, Alexandrov, Ludmil B, Somers, Gino R, Schiffman, Joshua D, Rotter, Varda, Malkin, David, Shlien, Adam
Published in Nature communications (05.01.2023)
Published in Nature communications (05.01.2023)
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Journal Article
Evaluation of Neoplasia, Treatments, and Survival in Lizard Species
Willig, Frank, Torpy, Fred J, Harrison, Scott H, Duke, Elizabeth G, Troan, Brigid, Boddy, Amy M, Abegglen, Lisa M, Harrison, Tara M
Published in Animals (Basel) (01.05.2024)
Published in Animals (Basel) (01.05.2024)
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Evolutionary determinants of curability in cancer
Mansur, Marcela Braga, deSouza, Nandita M, Natrajan, Rachael, Abegglen, Lisa M, Schiffman, Joshua D, Greaves, Mel
Published in Nature ecology & evolution (01.11.2023)
Published in Nature ecology & evolution (01.11.2023)
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Journal Article
DNA copy number analysis of Grade II-III and Grade IV gliomas reveals differences in molecular ontogeny including chromothripsis associated with IDH mutation status
Cohen, Adam, Sato, Mariko, Aldape, Kenneth, Mason, Clinton C, Alfaro-Munoz, Kristin, Heathcock, Lindsey, South, Sarah T, Abegglen, Lisa M, Schiffman, Joshua D, Colman, Howard
Published in Acta neuropathologica communications (20.06.2015)
Published in Acta neuropathologica communications (20.06.2015)
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Journal Article
Of Elephants and Other Mammals: A Comparative Review of Reproductive Tumors and Potential Impact on Conservation
Abegglen, Lisa M, Harrison, Tara M, Moresco, Anneke, Fowles, Jared S, Troan, Brigid V, Kiso, Wendy K, Schmitt, Dennis, Boddy, Amy M, Schiffman, Joshua D
Published in Animals (Basel) (08.08.2022)
Published in Animals (Basel) (08.08.2022)
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Journal Article
Germline mutation rate predicts cancer mortality across 37 vertebrate species
Kapsetaki, Stefania E, Compton, Zachary T, Mellon, Walker, Vincze, Orsolya, Giraudeau, Mathieu, Harrison, Tara M, Abegglen, Lisa M, Boddy, Amy M, Maley, Carlo C, Schiffman, Joshua D
Published in Evolution, medicine, and public health (01.01.2024)
Published in Evolution, medicine, and public health (01.01.2024)
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Journal Article
Elephant TP53-RETROGENE 9 induces transcription-independent apoptosis at the mitochondria
Preston, Aidan J, Rogers, Aaron, Sharp, Miranda, Mitchell, Gareth, Toruno, Cristhian, Barney, Brayden B, Donovan, Lauren N, Bly, Journey, Kennington, Ryan, Payne, Emily, Iovino, Anthony, Furukawa, Gabriela, Robinson, Rosann, Shamloo, Bahar, Buccilli, Matthew, Anders, Rachel, Eckstein, Sarah, Fedak, Elizabeth A, Wright, Tanner, Maley, Carlo C, Kiso, Wendy K, Schmitt, Dennis, Malkin, David, Schiffman, Joshua D, Abegglen, Lisa M
Published in Cell death discovery (16.02.2023)
Published in Cell death discovery (16.02.2023)
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Journal Article
Abstract 3686: Elephant TP53 (ep53) retrogene protein expression enhances cellular apoptosis in response to DNA damage
Abegglen, Lisa M., Robinson, Rosann, Donovan, Lauren, Caulin, Aleah F., Goldfeder, Mor, Schroeder, Avi, Maley, Carlo C., Schiffman, Joshua D.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article
C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells
Gardiner, Jamie D, Abegglen, Lisa M, Huang, Xiaomeng, Carter, Bryce E, Schackmann, Elizabeth A, Stucki, Marcus, Paxton, Christian N, Lor Randall, R, Amatruda, James F, Putnam, Angelica R, Kovar, Heinrich, Lessnick, Stephen L, Schiffman, Joshua D
Published in Oncotarget (18.04.2017)
Published in Oncotarget (18.04.2017)
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